Journals / Epilepsi / 2019 / Cilt: 25 - Sayı: 2

Development of Psychosis in Two Cases with Epilepsy Diagnosis: Clinical Findings, Magnetic Resonance Imaging Features, and Neuropsychological Assessment

Epilepsi Tanısı İle Tedavi Edilen İki Olguda Psikoz Gelişimi: Kliniği, Manyetik Rezonans Özellikleri ve Nöropsikolojik Değerlendirme

Journal
Epilepsi
Pages
102–107
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Forced normalization is an important concept for continued discussion.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Epilepsy-related psychosis is generally separated into 3 subgroups: postictal, interictal, and bimodal psychosis.
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Key Findings & Data:However, if the psychosis continues for 1 month or longer, it is defined as chronic schizophrenia-like psychosis.
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Conclusion & Impact:Forced normalization is an important concept for continued discussion.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Epilepsy-related psychosis is generally separated into 3 subgroups: postictal, interictal, and bimodal psychosis. However, if the psychosis continues for 1 month or longer, it is defined as chronic schizophrenia-like psychosis. It tends to occur 10 to 15 years after the onset of epilepsy, and cannot easily be distinguished from schizophrenia. In controlled trials, the risk of developing a psychotic disorder was 10-times higher in epileptic patients than in patients with other neurological disorders. In this presentation, 2 patients with epilepsy and chronic schizophrenia-like psychosis were diagnosed according to clinical and radiological findings. In both cases, psychotic symptoms appeared after the onset of epileptic seizures. Delusions and hallucinations were present as positive symptomatology. The intensity and severity of epileptic seizures decreased after the onset of psychotic symptoms in both cases. Forced normalization is an important concept for continued discussion.

Özet

Epilepsiye bağlı psikoz üç alt gruba ayrılarak değerlendirilir: postiktal, interiktal ve bimodal psikoz. Ancak psikoz atağı en az bir ay veya daha uzun süre devam ediyorsa kronik şizofreni benzeri psikoz olarak tanımlanır. Sıklıkla epilepsinin başlangıcından 10–15 yıl sonra ortaya çıkma eğilimindedir ve şizofreniden ayırt edilemezler. Kontrollü çalışmalarda da epilepsi hastalarında psikotik bozuklukların gelişme riski diğer nörolojik hastalıklarla kıyaslandığında on kat daha yüksektir. Bu sunumda kronik şizofreni benzeri psikoz gelişen iki epilepsi olgusunun klinik ve radyolojik inceleme sonuçlarına göre tanı koydurucu özelliklerini gözden geçirdik. İki olguda da psikotik semptomlar, epileptik nöbetlerin başlangıcından sonra ortaya çıkmıştı. Pozitif semptomatoloji olarak delüzyon ve halüsinasyon mevcuttu. Her iki olgumuzda da psikotik belirtilerin ortaya çıkmasından sonra epileptik nöbetlerin yoğunluğunun ve şiddetinin azaldığı görüldü. Böylece psikiyatrik bozukluklar ve epilepsi ilişkisinde zorunlu normalizasyon kavramı önemli bir fenomen olarak tartışılabilmektedir.

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Cite This Article

ALİ, A., GÜNGÖR, B. B., BUDAK, E., HAKİ, C., TAYMUR, İ., YALÇIN, R. (2019). Development of Psychosis in Two Cases with Epilepsy Diagnosis: Clinical Findings, Magnetic Resonance Imaging Features, and Neuropsychological Assessment. Epilepsi, Cilt: 25 - Sayı: 2, 102–107. https://ajindex.com/articles/150779

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