Journals / Journal of Anatolian Medical Research / 2025 / Cilt: 10 Sayı: 3

Use of Anticoagulants and Recurrent Ischemic Stroke Despite Severe Thrombocytopenia: A Rare Case Presentation

Ciddi Trombositopeniye Rağmen Antikoagülan Kullanımı ve Tekrarlayan İskemik İnme: Nadir Bir Olgu Sunumu

Nazmiye Serap Biçer(Kayseri Şehir Hastanesi)0000-0001-8762-2571
Hilal Sipahioğlu(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, KAYSERİ SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0002-7884-2094
Sümeyra Koyuncu(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, KAYSERİ SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0002-1159-5818
Bengisu Gedikli(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, KAYSERİ SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0009-0004-7117-948X
Pages
99–101
Publication Date
2025-12-31
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

She was investigated for thrombocytopenia presented in her admission and given corticosteroid therapy for suspected idiopathic thrombocytopenic purpura (ITP), which did not respond, but her thrombocytopenia was corrected with eltrombopag therapy, and she was successfully managed with antiaggregant anticoagulant therapy.

📌 3 Key Takeaways

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Objective & Hypothesis:This case report examines a rare patient who experienced recurrent ischemic stroke despite severe thrombocytopenia and the use of anticoagulant therapy.
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Key Findings & Data:The emphasis is placed on the use and safety of anticoagulant therapy and strategies for managing ischemic stroke in patients with hematologic abnormalities.
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Conclusion & Impact:She was investigated for thrombocytopenia presented in her admission and given corticosteroid therapy for suspected idiopathic thrombocytopenic purpura (ITP), which did not respond, but her thrombocytopenia was corrected with eltrombopag therapy, and she was successfully managed with antiaggregant anticoagulant therapy.
🔬Design:Olgu Sunumu
📍Scope:Comprehensive Sample
⚙️Variables:Antikoagülanlar · iskemik inme · kan hastalıkları

Abstract

This case report examines a rare patient who experienced recurrent ischemic stroke despite severe thrombocytopenia and the use of anticoagulant therapy. The patient's clinical course was characterized by recurrent ischemic events despite the bleeding risks associated with thrombocytopenia. Diagnostic evaluations and the treatment process are discussed, highlighting the clinical management challenges in such complex cases. The emphasis is placed on the use and safety of anticoagulant therapy and strategies for managing ischemic stroke in patients with hematologic abnormalities. She was investigated for thrombocytopenia presented in her admission and given corticosteroid therapy for suspected idiopathic thrombocytopenic purpura (ITP), which did not respond, but her thrombocytopenia was corrected with eltrombopag therapy, and she was successfully managed with antiaggregant anticoagulant therapy.

Özet

Bu olgu sunumu, ciddi trombositopeniye ve devam eden antikoagülan tedaviye rağmen tekrarlayan iskemik inme geçiren nadir bir hastayı ele almaktadır. Hastanın klinik seyri, trombositopeniye bağlı kanama riskine karşın gelişen tekrarlayan iskemik olaylarla karakterizedir. Tanısal değerlendirmeler ve tedavi süreci ayrıntılı olarak sunulmakta; bu tür karmaşık klinik olgularda yönetim stratejilerinin zorluklarına vurgu yapılmaktadır. Özellikle hematolojik bozukluklara sahip hastalarda antikoagülan tedavi kullanımı ve güvenliği ile iskemik inmeye yaklaşım stratejileri ön plana çıkarılmıştır. Başvuru sırasında tespit edilen trombositopeni nedeniyle hastaya öncelikle idiyopatik trombositopenik purpura (ITP) ön tanısıyla kortikosteroid tedavisi başlanmış; ancak klinik yanıt alınamamıştır. Daha sonra eltrombopag tedavisine geçilmiş ve trombositopeni bu tedaviyle düzeltilmiştir. Bu gelişmelerin ardından hasta antiagregan ve antikoagülan tedaviyle güvenli şekilde izlenmiş ve başarılı bir şekilde yönetilmiştir. Bu vaka, hematolojik bozukluklara rağmen bireyselleştirilmiş tedavi yaklaşımlarıyla iskemik inme yönetiminin nasıl güvenli biçimde uygulanabileceğine dair özgün bulgular sunmaktadır.

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Cite This Article

Biçer, N. S., Sipahioğlu, H., Koyuncu, S., Gedikli, B. (2025). Use of Anticoagulants and Recurrent Ischemic Stroke Despite Severe Thrombocytopenia: A Rare Case Presentation. Journal of Anatolian Medical Research, Cilt: 10 Sayı: 3, 99–101. https://doi.org/10.55694/jamer.1726792

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