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Journals / Astım Allerji İmmünoloji / 2017 / Cilt: 15 - Sayı: 3

Rare Differential Diagnosis for Acute Urticarial Plaques: Adult Onset Still's Disease

Akut Ürtikeryal Plaklarda Bir Ayırıcı Tanı: Erişkin Başlangıclı Still Hastalığı

Ayşe CEFLE ERGÜNEYZ
Emek KOCATÜRK
Duygu TEMİZ KARADAĞZ
Sule GÜNGÖRL
Nilgün BAHÇETEPE HÖKENEKL
Mehmet ÇOPURL
Pırıl ETİKAN AKBAŞL
Pages
154–159
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

AOSD should be kept in mind in persistent urticarial skin rash with accompanying spiking fever.

📌 3 Key Takeaways

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Objective & Hypothesis:Adult-onset Still's disease (AOSD) was first described by Bywaters as a different clinical entity from Juvenile Rheumatoid Arthritis (Still's Disease).
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Key Findings & Data:It is an uncommon, acute, systemic inflammatory disease of unknown etiology, which is characterized by a high spiking fever (>=39°C), typical skin rash with an evanescent salmon-pink erythema, leukocytosis, arthritis/arthralgia, hepatosplenomegaly, lymphadenopathy, leukocytosis, sore throat and serositis.
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Conclusion & Impact:AOSD should be kept in mind in persistent urticarial skin rash with accompanying spiking fever.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Adult-onset Still's disease (AOSD) was first described by Bywaters as a different clinical entity from Juvenile Rheumatoid Arthritis (Still's Disease). It is an uncommon, acute, systemic inflammatory disease of unknown etiology, which is characterized by a high spiking fever (>=39°C), typical skin rash with an evanescent salmon-pink erythema, leukocytosis, arthritis/arthralgia, hepatosplenomegaly, lymphadenopathy, leukocytosis, sore throat and serositis. We report two patients in whom urticaria-like rash and angioedema were uncommon presenting features of AOSD where treatment was attempted with antihistamines and systemic steroids. AOSD should be kept in mind in persistent urticarial skin rash with accompanying spiking fever.

Özet

Erişkin başlangıçlı Still hastalığı (EBSH) ilk olarak Bywaters tarafından çocuklarda görülen Juvenil Romatoid Artrit'ten (Still Hastalığı) farklı bir klinik tablo olarak tanımlanmıştır. EBSH genellikle zor tanı konulan, etiyolojisi tam olarak bilinmeyen, genç erişkinleri etkileyen ve nadir görülen bir romatolojik hastalıktır. Akşamları yükselen sivri patern ateş (>=39°C), karakteristik olarak somon renginde, geçici eritemli, makülopapüler döküntü, artrit/artralji, hepatosplenomegali, lenfadenopati, lökositoz, boğaz ağrısı ve serozit ile karakterizedir. Yazıda, akut ürtiker ve anjiyoödem tanısıyla sistemik steroid ve antihistaminik tedavileri ile tam düzelmeyen ve yapılan ileri tetkikler ışığında EBSH tanısı alan iki olgu paylaşılmaktadır. Akşamları yükselen ateşe eşlik eden inatçı ürtikeryal lezyonların ayırıcı tanısında EBSH mutlaka akılda bulundurulmalıdır.

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Cite This Article

ERGÜNEYZ, A. C., KOCATÜRK, E., KARADAĞZ, D. T., GÜNGÖRL, S., HÖKENEKL, N. B., ÇOPURL, M., AKBAŞL, P. E. (2017). Rare Differential Diagnosis for Acute Urticarial Plaques: Adult Onset Still's Disease. Astım Allerji İmmünoloji, Cilt: 15 - Sayı: 3, 154–159. https://ajindex.com/articles/147398

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