Journals / Cerrahi Sanatlar Dergisi / 2026 / Cilt: 18 Sayı: 1

Retrospective analysis of patients with paramalignant and malignant pleural effusion

Paramalign ve malign plevral sıvısı olan hastaların retrospektif analizi

Ayten Güner Akbıyık(profesör doktor süleymen yalçın şehir hastanesi)0000-0003-0177-2056
Temmuz Baran Şencan(ISTANBUL MEDENIYET UNIVERSITY, SCHOOL OF MEDICINE)0009-0004-8554-1101
Deniz Koçak(İSTANBUL MEDENİYET ÜNİVERSİTESİ)0009-0002-0290-7063
Coşkun Doğan(İSTANBUL MEDENİYET ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0002-6948-5187
Tahir Şevval Eren(İSTANBUL MEDENİYET ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0003-3331-5511
Pages
14–19
Publication Date
2025-01-21
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Although we could not reach statistically significant data as a result of our study, we believe that different results can be obtained in terms of biochemical results and pleural effusion FDG uptake when large-scale studies are performed with a larger number of patients.

📌 3 Key Takeaways

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Objective & Hypothesis:ABSTRACT Aim: Pleural effusion (PE) is an important clinical condition with an increasing incidence and can occur due to various causes.
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Key Findings & Data:Materials and Methods: In this study, 477 patients who underwent thoracentesis in the pulmonology and thoracic surgery clinics were analyzed.
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Conclusion & Impact:Conclusion: Although we could not reach statistically significant data as a result of our study, we believe that different results can be obtained in terms of biochemical results and pleural effusion FDG uptake when large-scale studies are performed with a larger number of patients.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:malign effüzyon · paramalign effüzyon · torasentez

Abstract

ABSTRACT Aim: Pleural effusion (PE) is an important clinical condition with an increasing incidence and can occur due to various causes. The aim of this study was to retrospectively analyze the radiologic, radiometabolic, histopathologic and biochemical findings of patients with malignant pleural effusion (MPE) and paramalignant pleural effusion (PMPE). Materials and Methods: In this study, 477 patients who underwent thoracentesis in the pulmonology and thoracic surgery clinics were analyzed. Patients were divided into 2 groups as MPE and PMPE. Data obtained by thoracentesis were compared between the two groups. Statistical analyses were performed using SPSS 17.0 program. Results: In our study, the files of 477 patients who underwent thoracentesis were evaluated. We excluded 313 patients diagnosed with benign pleural effusion and 96 patients whose PET-CT reports were not available. A total of 68 patients, 29 (42.6%) of whom were women with a mean age of 65.7±10.1 years, were included in the study. PS albumin value was 23.7±10.8 in group 1 and 18±13.2 in group 2 with a p value of 0.055, which was not statistically significant. PS LDH value was 558±616.9 in group 1 and 369.8±520.9 in group 2. No statistically significant difference was found between the two groups when biochemical, radiologic, radiometabolic and histopathologic data were evaluated. Conclusion: Although we could not reach statistically significant data as a result of our study, we believe that different results can be obtained in terms of biochemical results and pleural effusion FDG uptake when large-scale studies are performed with a larger number of patients.

Özet

Amaç: Giderek artan insidansa sahip olan plevral sıvılar (PS), önemli bir klinik durumdur ve çeşitli nedenlere bağlı olarak ortaya çıkabilir. Bu çalışmanın amacı, malign plevral sıvı (MPS) ve paramalign plevral sıvı (PMPS) tanısı alan hastaların radyolojik histopatolojik ve biyokimyasal değerlerinin retrospektif olarak incelemektir. Gereç ve Yöntemler: Bu çalışmada göğüs hastalıkları ve göğüs cerrahisi kliniklerinde tanısal torasentez yapılmış 477 hasta incelendi. Hastalar MPS ve PMPS olmak üzere 2 gruba ayrıldı. Torasentez işlemi ile elde edilen veriler iki grup arasında karşılaştırıldı. İstatistiksel analizler SPSS 17.0 programı kullanılarak yapıldı. Bulgular: Çalışmamızda torasentez yapılan 477 hastanın dosyası incelendi. Benign plevral sıvı tanısı alan 313 olgu ve PET-BT raporuna ulaşılamayan 96 olgu çalışma dışı bırakıldı. Çalışmaya yaş ortalaması 65,7±10,1 olan 29’u (%42,6) kadın toplam 68 olgu dahil edildi. PS albümin değeri grup 1 de 23,7±10,8, grup 2 de 18±13,2 ile p değeri 0,055 bulunarak istatistiksel olarak anlamlı bulunmadı. PS LDH değeri grup 1 de 558±616, grup 2 de 369,8±520,9 olarak görüldü Her iki grup arasında biyokimyasal, radyolojik ve histopatolojik veriler değerlendirildiğinde istatistiksel olarak anlamlı fark bulunamadı. Sonuç: Araştırmamızın sonucunda istatistiksel olarak anlamlı verilere ulaşamasak ta daha fazla sayıda hasta ile geniş ölçekli çalışmalar yapıldığında biyokimyasal sonuçlar ve plevral sıvı FDG tutulumları açısından farklı sonuçlar elde edilebileceğine inanıyoruz. Anahtar Kelimeler: Paramalign plevral sıvı; malign plevral sıvı; torasentez

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Cite This Article

Akbıyık, A. G., Şencan, T. B., Koçak, D., Doğan, C., Eren, T. Ş. (2025). Retrospective analysis of patients with paramalignant and malignant pleural effusion. Cerrahi Sanatlar Dergisi, Cilt: 18 Sayı: 1, 14–19. https://ajindex.com/articles/1469099

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