Journals / Balıkesir Sağlık Bilimleri Dergisi / 2026 / Volume: 14 Issue: 2

Muscle Strength, Mobility, Activities of Daily Living and Depression in Relation to Frailty in Older Adults

Yaşlı Yetişkinlerde Kas Kuvveti, Mobilite, Günlük Yaşam Aktiviteleri ve Depresyonun Kırılganlıkla İlişkisi

Taşkın Özkan(GİRESUN ÜNİVERSİTESİ)0000-0001-9448-0516
Ülkü Kezban Şahin(GİRESUN ÜNİVERSİTESİ)0000-0001-8972-4774
Arzu Ayraler(GİRESUN ÜNİVERSİTESİ)0000-0002-5244-7571
Alican Yılmaz(Giresun Eğitim ve Araştırma Hastanesi)0009-0007-1109-5745
Pages
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Publication Date
2025-08-30
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Therefore, even in the absence of frailty symptoms, lower extremity muscle strength, functional mobility, instrumental-ADL, and depression should be evaluated at regular intervals in order to prevent the emergence of frailty or stop its progression in older adults, and we think that treatment approaches to improve these parameters should be included in geriatric rehabilitation practices.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Examining the relationship between frailty and lower extremity muscle strength, functional mobility, activities of daily living (ADL), and depression in older adults was the goal of this study.
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Key Findings & Data:Materials and Methods: There were 69 older adults in the cross-sectional study (35 male and 34 female).
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Conclusion & Impact:Therefore, even in the absence of frailty symptoms, lower extremity muscle strength, functional mobility, instrumental-ADL, and depression should be evaluated at regular intervals in order to prevent the emergence of frailty or stop its progression in older adults, and we think that treatment approaches to improve these parameters should be included in geriatric rehabilitation practices.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Frailty · Muscle Strength · Mobility

Abstract

Objective: Examining the relationship between frailty and lower extremity muscle strength, functional mobility, activities of daily living (ADL), and depression in older adults was the goal of this study. Materials and Methods: There were 69 older adults in the cross-sectional study (35 male and 34 female). The Clinical Frailty Scale (CFS), 5-Repetition Sit-to-Stand (STS) Test, Timed Up and Go (TUG) Test, Lawton Instrumental Activities of Daily Living (L-IADL) Scale and Geriatric Depression Scale-Short Form (GDS-SF) were used for evaluations. Results: The mean and standard deviation age value of the older adults was 85.48±3.67 years and the body mass index was 25.73 ± 3.01 kg/m2. In older adults, the CFS was positively and moderately associated with the 5-STS Test (rho=0.418, p < 0.001) and TUG Test (rho=0.573, p < 0.001), negatively associated with the L-IADL Scale at good level (rho=-0.637, p < 0.001), and positively correlated with GDS-SF at fair level (rho=0.281, p=0.019) in older adults. Conclusion: Our research shows that frailty is associated with lower extremity muscle strength, functional mobility, ADL and depression in older adults. Therefore, even in the absence of frailty symptoms, lower extremity muscle strength, functional mobility, instrumental-ADL, and depression should be evaluated at regular intervals in order to prevent the emergence of frailty or stop its progression in older adults, and we think that treatment approaches to improve these parameters should be included in geriatric rehabilitation practices.

Özet

Amaç: Bu çalışmanın amacı yaşlı bireylerde kırılganlık ile alt ekstremite kas kuvveti, fonksiyonel mobilite, günlük yaşam aktiviteleri (GYA) ve depresyon arasındaki ilişkiyi incelemektir. Gereç ve Yöntem: Bu kesitsel çalışmaya 69 yaşlı birey (34 kadın ve 35 erkek) dahil edildi. Değerlendirmeler için Klinik Kırılganlık Ölçeği (KKÖ), 5-Tekrarlı Otur-Kalk Testi (5-OKT), Süreli Kalk ve Yürü (TUG) Testi, Lawton Enstrümantal Günlük Yaşam Aktiviteleri (L-EGYA) Ölçeği ve Geriatrik Depresyon Ölçeği-Kısa Formu (GDÖ-KF) kullanıldı. Bulgular: Yaşlı bireylerin ortalama ve standart sapma yaş değeri 85.48±3.67 ve vücut kütle indeksi 25.73 ± 3.01 kg/m2 idi. Yaşlı bireylerde KKÖ, 5-OKT (rho=0.418, p < 0.001) ve TUG Testi (rho=0.573, p < 0.001) ile pozitif yönde ve orta düzeyde ilişkili, L-EGYA Ölçeği ile iyi düzeyde ve negatif yönde ilişkili (rho=-0.637, p < 0.001) ve GDÖ-KF ile orta düzeyde ve pozitif yönde ilişkili (rho=0.281, p=0.019) bulunmuştur. Sonuç: Çalışmamız, yaşlı bireylerde kırılganlığın alt ekstremite kas kuvveti, fonksiyonel mobilite, GYA ve depresyon ile ilişkili olduğuna dair kanıtlar sunmaktadır. Bu nedenle, yaşlı bireylerde kırılganlık belirtileri olmasa bile, kırılganlığın ortaya çıkmasını önlemek veya ilerleyişini durdurmak amacıyla, yürüyüş, alt ekstremite kas kuvveti, depresyon ve enstrümental günlük yaşam aktiviteleri düzenli aralıklarla değerlendirilmelidir ve bu parametreleri iyileştirmeye yönelik tedavi yaklaşımlarının geriatrik rehabilitasyon uygulamalarına dahil edilmesi gerektiğini düşünmekteyiz.

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Cite This Article

Özkan, T., Şahin, Ü. K., Ayraler, A., Yılmaz, A. (2025). Muscle Strength, Mobility, Activities of Daily Living and Depression in Relation to Frailty in Older Adults. Balıkesir Sağlık Bilimleri Dergisi, Volume: 14 Issue: 2. https://doi.org/10.53424/balikesirsbd.1685174

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References (39)

  1. Aslan, U. B., Cavlak, U., Yagci, N., & Akdag, B. (2008). Balance performance, aging and falling: a comparative study based on a Turkish sample. Archives of Gerontology and Geriatrics, 46(3), 283-292. https://doi.org/10.1016/j.archger.2007.05.003
  2. Batista, F. S., Gomes, G. A. d. O., D'Elboux, M. J., Cintra, F. A., Neri, A. L., Guariento, M. E., & Souza, M. d. L. R. d. (2014). Relationship between lower-limb muscle strength and functional independence among elderly people according to frailty criteria: a cross-sectional study. Sao Paulo Medical Journal, 132(05), 282-289. https://doi.org/10.1590/1516-3180.2014.1325669
  3. Batista, F. S., Gomes, G. A. d. O., Neri, A. L., Guariento, M. E., Cintra, F. A., Sousa, M. d. L. R. d., & D'Elboux, M. J. (2012). Relationship between lower-limb muscle strength and frailty among elderly people. Sao Paulo Medical Journal, 130, 102-108. https://doi.org/10.1590/s1516-31802012000200006
  4. Baysal, G., & Saka, S. (2024). Association of Frailty, Balance, and Depression with Activities of Daily Living in Older Adults. Topics in Geriatric Rehabilitation, 40(3), 186-190. https://doi.org/10.1097/TGR.0000000000000440
  5. Beauchet, O., Fantino, B., Allali, G., Muir, S., Montero-Odasso, M., & Annweiler, C. (2011). Timed Up and Go test and risk of falls in older adults: a systematic review. The Journal of Nutrition, Health & Aging, 15, 933-938. https://doi.org/10.1007/s12603-011-0062-0
  6. Buckinx, F., Reginster, J.-Y., Petermans, J., Croisier, J.-L., Beaudart, C., Brunois, T., & Bruyère, O. (2016). Relationship between frailty, physical performance and quality of life among nursing home residents: the SENIOR cohort. Aging Clinical and Experimental Research, 28, 1149-1157. https://doi.org/10.1007/s40520-016-0616-4
  7. Buigues, C., Padilla-Sánchez, C., Garrido, J. F., Navarro-Martínez, R., Ruiz-Ros, V., & Cauli, O. (2015). The relationship between depression and frailty syndrome: a systematic review. Aging & Mental Health, 19(9), 762-772. https://doi.org/10.1080/13607863.2014.967174
  8. Castell, M.-V., Sánchez, M., Julián, R., Queipo, R., Martín, S., & Otero, Á. (2013). Frailty prevalence and slow walking speed in persons age 65 and older: implications for primary care. BMC Family Practice, 14, 1-9. https://doi.org/10.1186/1471-2296-14-86
  9. Church, S., Rogers, E., Rockwood, K., & Theou, O. (2020). A scoping review of the Clinical Frailty Scale. BMC Geriatrics, 20, 1-18. https://doi.org/10.1186/s12877-020-01801-7
  10. Davis, D. H., Rockwood, M. R., Mitnitski, A. B., & Rockwood, K. (2011). Impairments in mobility and balance in relation to frailty. Archives of Gerontology and Geriatrics, 53(1), 79-83. https://doi.org/10.1016/j.archger.2010.06.013
  11. Durmaz, B., Soysal, P., Ellidokuz, H., & Isik, A. T. (2018). Validity and reliability of geriatric depression scale-15 (short form) in Turkish older adults. North Clin Istanb, 5(3), 216-220. https://doi.org/10.14744/nci.2017.85047
  12. Faul, F., Erdfelder, E., Buchner, A., & Lang, A. G. (2009). Statistical power analyses using G* Power 3.1: Tests for correlation and regression analyses. Behavior research methods, 41(4), 1149-1160. https://doi.org/10.3758/BRM.41.4.1149
  13. Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975). “Mini-mental state”: a practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research, 12(3), 189-198. https://doi.org/10.1016/0022-3956(75)90026-6
  14. Graf, C. (2009). The Lawton instrumental activities of daily living (IADL) scale. Medsurg Nurs, 18(5), 315-316.
  15. Hartley, P., Keevil, V. L., & Romero-Ortuno, R. (2017). The association between clinical frailty and walking speed in older hospitalized medical patients: A retrospective observational study. European Geriatric Medicine, 8(2), 130-133. https://doi.org/10.1016/j.eurger.2017.01.005
  16. Ji, D., Guo, H., Qiu, S., Dong, L., Shen, Y., Shen, Z., & Xu, J. (2024). Screening for frailty and its association with activities of daily living, cognitive impairment, and falls among community-dwelling older adults in China. BMC Geriatrics, 24(1), 576. https://doi.org/10.1186/s12877-024-05173-0
  17. Ji, L., Qiao, X., Jin, Y., Si, H., Liu, X., & Wang, C. (2020). Age differences in the relationship between frailty and depression among community-dwelling older adults. Geriatric Nursing, 41(4), 485-489. https://doi.org/10.1016/j.gerinurse.2020.01.021
  18. Kawai, H., Obuchi, S., Watanabe, Y., Hirano, H., Fujiwara, Y., Ihara, K.,. Tsushima, E. (2020). Association between daily living walking speed and walking speed in laboratory settings in healthy older adults. International Journal of Environmental Research and Public Health, 17(8), 2707. https://doi.org/10.3390/ijerph17082707
  19. Muñoz-Bermejo, L., Adsuar, J. C., Mendoza-Muñoz, M., Barrios-Fernández, S., Garcia-Gordillo, M. A., Pérez-Gómez, J., & Carlos-Vivas, J. (2021). Test-retest reliability of five times sit to stand test (FTSST) in adults: a systematic review and meta-analysis. Biology, 10(6), 510. https://doi.org/10.3390/biology10060510
  20. Navarrete-Villanueva, D., Gómez-Cabello, A., Marín-Puyalto, J., Moreno, L. A., Vicente-Rodríguez, G., & Casajús, J. A. (2021). Frailty and physical fitness in elderly people: a systematic review and meta-analysis. Sports Medicine, 51, 143-160. https://doi.org/10.1007/s40279-020-01361-1
  21. Ottenbacher, K. J., Ostir, G. V., Peek, M. K., Snih, S. A., Raji, M. A., & Markides, K. S. (2005). Frailty in older mexican americans. Journal of the American Geriatrics Society, 53(9), 1524-1531. https://doi.org/10.1111/j.1532-5415.2005.53511.x
  22. Papiol, M., Serra-Prat, M., Vico, J., Jerez, N., Salvador, N., Garcia, M.,. López, J. (2016). Poor muscle strength and low physical activity are the most prevalent frailty components in community-dwelling older adults. Journal of Aging and Physical Activity, 24(3), 363-368. https://doi.org/10.1123/japa.2015-0114
  23. Pashmdarfard, M., & Azad, A. (2020). Assessment tools to evaluate Activities of Daily Living (ADL) and Instrumental Activities of Daily Living (IADL) in older adults: A systematic review. Medical journal of the Islamic Republic of Iran, 34, 33. https://doi.org/10.34171/mjiri.34.33
  24. Pradeep Kumar, D., Toosizadeh, N., Mohler, J., Ehsani, H., Mannier, C., & Laksari, K. (2020). Sensor-based characterization of daily walking: a new paradigm in pre-frailty/frailty assessment. BMC Geriatrics, 20, 1-11. https://doi.org/10.1186/s12877-020-01572-1
  25. Provencher, V., Béland, F., Demers, L., Desrosiers, J., Bier, N., Ávila-Funes, J. A.,. Trottier, L. (2017). Are frailty components associated with disability in specific activities of daily living in community-dwelling older adults? A multicenter Canadian study. Archives of Gerontology and Geriatrics, 73, 187-194. https://doi.org/10.1016/j.archger.2017.07.027
  26. Purser, J. L., Kuchibhatla, M. N., Fillenbaum, G. G., Harding, T., Peterson, E. D., & Alexander, K. P. (2006). Identifying frailty in hospitalized older adults with significant coronary artery disease. Journal of the American Geriatrics Society, 54(11), 1674-1681. https://doi.org/10.1111/j.1532-5415.2006.00914.x
  27. Rockwood, K., Song, X., MacKnight, C., Bergman, H., Hogan, D. B., McDowell, I., & Mitnitski, A. (2005). A global clinical measure of fitness and frailty in elderly people. Cmaj, 173(5), 489-495. https://doi.org/10.1503/cmaj.050051
  28. Rydwik, E., Bergland, A., Forsén, L., & Frändin, K. (2011). Psychometric properties of timed up and go in elderly people: a systematic review. Physical & Occupational Therapy in Geriatrics, 29(2), 102-125. https://doi.org/10.3109/02703181.2011.564725
  29. Shimada, H., Makizako, H., Doi, T., Tsutsumimoto, K., & Suzuki, T. (2015). Incidence of disability in frail older persons with or without slow walking speed. Journal of the American Medical Directors Association, 16(8), 690-696. https://doi.org/10.1016/j.jamda.2015.03.019
  30. Soysal, P., Veronese, N., Thompson, T., Kahl, K. G., Fernandes, B. S., Prina, A. M.,. Tseng, P.-T. (2017). Relationship between depression and frailty in older adults: a systematic review and meta-analysis. Ageing Research Reviews, 36, 78-87. https://doi.org/10.1016/j.arr.2017.03.005
  31. Theou, O., Jones, G. R., Jakobi, J. M., Mitnitski, A., & Vandervoort, A. A. (2011). A comparison of the relationship of 14 performance-based measures with frailty in older women. Applied Physiology, Nutrition, and Metabolism, 36(6), 928-938. https://doi.org/10.1139/h11-116
  32. Theou, O., Rockwood, M. R., Mitnitski, A., & Rockwood, K. (2012). Disability and co-morbidity in relation to frailty: how much do they overlap? Archives of Gerontology and Geriatrics, 55(2), e1-e8. https://doi.org/10.1016/j.archger.2012.03.00
  33. Tornero-Quiñones, I., Sáez-Padilla, J., Espina Díaz, A., Abad Robles, M. T., & Sierra Robles, Á. (2020). Functional ability, frailty and risk of falls in the elderly: relations with autonomy in daily living. International Journal of Environmental Research and Public Health, 17(3), 1006. https://doi.org/10.3390/ijerph17031006
  34. Tsekoura, M., Anastasopoulos, K., Kastrinis, A., & Dimitriadis, Z. (2020). What is most appropriate number of repetitions of the sit-to-stand test in older adults: a reliability study. Journal of Frailty, Sarcopenia and Falls, 5(4), 109. https://doi.org/10.22540/JFSF-05-109
  35. Yin, H., Gao, C., Quan, Z., & Zhang, Y. (2023). The relationship between frailty, walking ability, and depression in elderly Chinese people. Medicine, 102(45), e35876. https://doi.org/10.1097/MD.0000000000035876
  36. Kawai, H., Obuchi, S., Watanabe, Y., Hirano, H., Fujiwara, Y., Ihara, K.,. Tsushima, E. (2020). Association between daily living walking speed and walking speed in laboratory settings in healthy older adults. International Journal of Environmental Research and Public Health, 17(8), 2707. https://doi.org/10.3390/ijerph17082707
  37. Papiol, M., Serra-Prat, M., Vico, J., Jerez, N., Salvador, N., Garcia, M.,. López, J. (2016). Poor muscle strength and low physical activity are the most prevalent frailty components in community-dwelling older adults. Journal of Aging and Physical Activity, 24(3), 363-368. https://doi.org/10.1123/japa.2015-0114
  38. Provencher, V., Béland, F., Demers, L., Desrosiers, J., Bier, N., Ávila-Funes, J. A.,. Trottier, L. (2017). Are frailty components associated with disability in specific activities of daily living in community-dwelling older adults? A multicenter Canadian study. Archives of Gerontology and Geriatrics, 73, 187-194. https://doi.org/10.1016/j.archger.2017.07.027
  39. Soysal, P., Veronese, N., Thompson, T., Kahl, K. G., Fernandes, B. S., Prina, A. M.,. Tseng, P.-T. (2017). Relationship between depression and frailty in older adults: a systematic review and meta-analysis. Ageing Research Reviews, 36, 78-87. https://doi.org/10.1016/j.arr.2017.03.005