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Journals / Balıkesir Sağlık Bilimleri Dergisi / 2026 / Volume: 15 Issue: 1

Holocord Syringomyelia due to Spinal Dysraphism without Chiari Malformation - A Case Report

Chiari Malformasyonu Olmayan Spinal Disrafiye Bağlı Holokord Siringomiyeli: Vaka Sunumu

Ali Samet Topsakal(KARADENİZ TEKNİK ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0003-3463-950X
Mehmet Orbay Bıyık(KARADENİZ TEKNİK ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0002-2506-8488
Mehmet Aktoklu(KARADENİZ TEKNİK ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0002-8721-5113
Ertuğrul Çakır(KARADENİZ TEKNİK ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0003-3164-8574
Pages
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Publication Date
2026-02-28
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We aimed to contribute to the literature by providing information about the treatment process of the patient.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Syringomyelia is a cystic enlargement of the spinal cord that causes myelopathy.
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Key Findings & Data:Although it may appear idiopathically, Type 1 and 2 Chiari, the Dandy-Walker syndrome cerebellar ectopia basilar impression basilar arachnoiditis, posterior fossa tumors and arachnoid cysts, medulla spinalis tumors, spinal trauma and infections are among the most common causes.
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Conclusion & Impact:We aimed to contribute to the literature by providing information about the treatment process of the patient.
🔬Design:Case Report
📍Scope:Comprehensive Sample
⚙️Variables:Malformation Arnold-Chiari · Tethered Cord Syndrome · Syringomyelia

Abstract

Syringomyelia is a cystic enlargement of the spinal cord that causes myelopathy. The commonly used classification is one based on anatomical features or pathogen other than pathophysiological mechanisms. Among the many pathophysiological theories, the most widely accepted is that disturbances in cerebrospinal fluid (CSF) flow in the lower arachnoid spaces disrupt flow velocity leading to syrinx. Although it may appear idiopathically, Type 1 and 2 Chiari, the Dandy-Walker syndrome cerebellar ectopia basilar impression basilar arachnoiditis, posterior fossa tumors and arachnoid cysts, medulla spinalis tumors, spinal trauma and infections are among the most common causes. Syringomyelia is mostly seen with type 1 Chiari malformation in patients. Based on this information, we present this rare patient with tethered cord and holocord syringomyelia without type 1 Chiari malformation. We aimed to contribute to the literature by providing information about the treatment process of the patient.

Özet

Siringomiyeli, miyelopatiye neden olan omuriliğin kistik genişlemesidir. Yaygın olarak kullanılan sınıflandırma, patofizyolojik mekanizmalar dışında anatomik özelliklere veya patojene dayanan bir sınıflandırmadır. Birçok patofizyolojik teori arasında en yaygın kabul göreni, alt araknoid boşluklardaki beyin omurilik sıvısı (BOS) akışındaki bozuklukların akış hızını bozarak syrinkse yol açmasıdır. İdiyopatik olarak ortaya çıkabilmesine rağmen, Tip 1 ve 2 Chiari, Dandy-Walker sendromu serebellar ektopi baziler izlenim baziler araknoidit, posterior fossa tümörleri ve araknoid kistler, medulla spinalis tümörleri, spinal travma ve enfeksiyonlar en sık nedenler arasındadır. Siringomiyeli hastalarda en sık tip 1 Chiari malformasyonu ile birlikte görülür. Bu bilgiler ışığında, tip 1 Chiari malformasyonu olmaksızın nadir görülen gergin kord ve holokord siringomiyeli olgusunu sunuyoruz. Hastanın tedavi süreci hakkında bilgi vererek literatüre katkı sağlamayı amaçladık.

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Cite This Article

Topsakal, A. S., Bıyık, M. O., Aktoklu, M., Çakır, E. (2026). Holocord Syringomyelia due to Spinal Dysraphism without Chiari Malformation - A Case Report. Balıkesir Sağlık Bilimleri Dergisi, Volume: 15 Issue: 1. https://doi.org/10.53424/balikesirsbd.1783164

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References (27)

  1. Ball, M. J., & Dayan, A. D. (1972). Pathogenesis of syringomyelia. Lancet (London, England), 2(7781), 799 801. https://doi.org/10.1016/S0140-6736(72)92152-6
  2. Batzdorf, U., Khoo, L. T., & McArthur, D. L. (2007). Observations on spine deformity and syringomyelia. Neurosurgery, 61(2), 370 377. https://doi.org/10.1227/01.NEU.0000279971.87437.1F
  3. Brickell, K. L., Anderson, N. E., Charleston, A. J., Hope, J. K. A., Bok, A. P. L., & Barber, P. A. (2006). Ethnic differences in syringomyelia in New Zealand. Journal of Neurology, Neurosurgery & Psychiatry, 77(8), 989 991. https://doi.org/10.1136/JNNP.2005.081240
  4. Bruzek, A. K., Starr, J., Garton, H. J. L., Muraszko, K. M., Maher, C. O., & Strahle, J. M. (2019). Syringomyelia in children with closed spinal dysraphism: long-term outcomes after surgical intervention. Journal of Neurosurgery: Pediatrics, 25(3), 319 325. https://doi.org/10.3171/2019.9.PEDS1944
  5. Erkan, K., Unal, F., & Kiris, T. (1999). Terminal syringomyelia in association with the tethered cord syndrome. Neurosurgery, 45(6), 1351 1360. https://doi.org/10.1097/00006123-199912000-00018
  6. Fernández, A. A., Guerrero, A. I., Martínez, M. I., Amado Vázquez, M. E., Fernández, J. B., Chesa I Octavio, E., … Ramón, J. R. (2009). Malformations of the craniocervical junction (chiari type i and syringomyelia: Classification, diagnosis and treatment). BMC Musculoskeletal Disorders, 10(SUPPL. 1), 1 11. https://doi.org/10.1186/1471-2474-10-S1-S1/TABLES/2
  7. Gardner, W. J., & Angel, J. (1958). The mechanism of syringomyelia and its surgical correction. Clinical neurosurgery, 6, 131 140. https://doi.org/10.1093/NEUROSURGERY/6.CN_SUPPL_1.131
  8. Greitz, D. (2006). Unraveling the riddle of syringomyelia. Neurosurgical Review, 29(4), 251 264. https://doi.org/10.1007/S10143-006-0029-5/FIGURES/3
  9. Honey, C. M., Martin, K. W., Heran, M. K. S., Honey, X. C. M., Martin, X. K. W., & Heran, X. M. K. S. (2017). Syringomyelia Fluid Dynamics and Cord Motion Revealed by Serendipitous Null Point Artifacts during Cine MRI. American Journal of Neuroradiology, 38(9), 1845 1847. https://doi.org/10.3174/AJNR.A5328
  10. Huang, H., Li, Y., Xu, K., Li, Y., Qu, L., & Yu, J. (2011). Foramen Magnum Arachnoid Cyst Induces Compression of the Spinal Cord and Syringomyelia: Case Report and Literature Review. International Journal of Medical Sciences, 8(4), 345. https://doi.org/10.7150/IJMS.8.345
  11. Iskandar, B. J., Oakes, W. J., McLaughlin, C., Osumi, A. K., & Tien, R. D. (1994). Terminal syringohydromyelia and occult spinal dysraphism. Journal of neurosurgery, 81(4), 513 519. https://doi.org/10.3171/JNS.1994.81.4.0513
  12. Kim, M. S., & Kim, S. H. (2009). Syringomyelia Associated with a Spinal Arachnoid Cyst. Journal of Korean Neurosurgical Society, 45(5), 315. https://doi.org/10.3340/JKNS.2009.45.5.315
  13. Koyanagi, I., & Houkin, K. (2010). Pathogenesis of syringomyelia associated with Chiari type 1 malformation: Review of evidences and proposal of a new hypothesis. Neurosurgical Review, 33(3), 271 285. https://doi.org/10.1007/S10143-010-0266-5/FIGURES/3
  14. Kulwin, C. G., Patel, N. B., Ackerman, L. L., Smith, J. L., Boaz, J. C., & Fulkerson, D. H. (2013). Radiographic and clinical outcome of syringomyelia in patients treated for tethered cord syndrome without other significant imaging abnormalities. Journal of neurosurgery. Pediatrics, 11(3), 307 312. https://doi.org/10.3171/2012.11.PEDS12251
  15. Leclerc, A., Matveeff, L., & Emery, E. (2021). Syringomyelia and hydromyelia: Current understanding and neurosurgical management. Revue Neurologique, 177(5), 498 507. https://doi.org/10.1016/J.NEUROL.2020.07.004
  16. Lee, J. Y., Kim, K. H., & Wang, K. C. (2020). Syringomyelia in the Tethered Spinal Cords. Journal of Korean Neurosurgical Society, 63(3), 338 341. https://doi.org/10.3340/JKNS.2020.0097
  17. Milhorat, T. H., Capocelli, A. L., Anzil, A. P., Kotzen, R. M., & Milhorat, R. H. (1995). Pathological basis of spinal cord cavitation in syringomyelia: analysis of 105 autopsy cases. Journal of Neurosurgery, 82(5), 802 812. https://doi.org/10.3171/JNS.1995.82.5.0802
  18. Milhorat, Thomas H., Chou, M. W., Trinidad, E. M., Kula, R. W., Mandell, M., Wolpert, C., & Speer, M. C. (1999). Chiari I malformation redefined: clinical and radiographic findings for 364 symptomatic patients. Neurosurgery, 44(5), 1005 1017. https://doi.org/10.1097/00006123-199905000-00042
  19. Mosleh, M. M., & Sohn, M. J. (2024). Optimizing Therapeutic Strategies for Syringomyelia Associated with Tethered Cord Syndrome: A Comprehensive Review. Children, 11(8), 961. https://doi.org/10.3390/CHILDREN11080961
  20. Oldfield, E. H., Muraszko, K., Shawker, T. H., & Patronas, N. J. (1994). Pathophysiology of syringomyelia associated with Chiari I malformation of the cerebellar tonsils: Implications for diagnosis and treatment. Journal of Neurosurgery, 80(1), 3 15. https://doi.org/10.3171/JNS.1994.80.1.0003
  21. Oldfield, Edward H. (2017). Pathogenesis of Chiari i - Pathophysiology of Syringomyelia: Implications for Therapy: A Summary of 3 Decades of Clinical Research. Clinical Neurosurgery, 64(CN), 66 77. https://doi.org/10.1093/NEUROS/NYX377
  22. Roser, F., Ebner, F. H., Sixt, C., Hagen, J. M. V., & Tatagiba, M. S. (2010). Defining the line between hydromyelia and syringomyelia. A differentiation is possible based on electrophysiological and magnetic resonance imaging studies. Acta Neurochirurgica, 152(2), 213 219. https://doi.org/10.1007/S00701-009-0427-X/FIGURES/5
  23. Roy, A. K., Slimack, N. P., & Ganju, A. (2011). Idiopathic syringomyelia: retrospective case series, comprehensive review, and update on management. Neurosurgical focus, 31(6). https://doi.org/10.3171/2011.9.FOCUS11198
  24. Takeuchi, A., Miyamoto, K., Sugiyama, S., Saitou, M., Hosoe, H., & Shimizu, K. (2003). Spinal Arachnoid Cysts Associated With Syringomyelia: Report of Two Cases and a Review of the Literature. Repéré à http://journals.lww.com/jspinaldisorders
  25. Tucer, B., Yilmaz, M. B., Ekici, M. A., Menku, A., & Koc, K. (2014). Spinal arachnoid cysts associated with syringomyelia: A review of the literature and report of a case. Turkish Neurosurgery, 24(4), 606 612. https://doi.org/10.5137/1019-5149.JTN.8700-13.0
  26. Weier, K., Naegelin, Y., Thoeni, A., Hirsch, J. G., Kappos, L., Steinbrich, W., … Gass, A. (2008). Non-communicating syringomyelia: a feature of spinal cord involvement in multiple sclerosis. Brain, 131(7), 1776 1782. https://doi.org/10.1093/BRAIN/AWN068
  27. Williams, B. (1972). Pathogenesis of syringomyelia. Lancet (London, England), 2(7784), 969 970. https://doi.org/10.1016/S0140-6736(72)92490-7