Journals / Astım Allerji İmmünoloji / 2018 / Cilt: 16 - Sayı: 3

Anaphylaxis Developoing after Measles Vaccine in an Infant with Cow’s Milk Allergy

İnek Sütü Allerjisi Olan Sütçocuğunda Kızamık Aşısı ile Gelişen Anafilaksi

Pages
171–174
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It might be dangerous to administer live attenuated measles vaccine to children diagnosed with cow’s milk allergy or to children suspected of being highly sensitive to cow’s milk proteins.

📌 3 Key Takeaways

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Objective & Hypothesis:Cow’s milk allergy is the most common food allergy in children.
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Key Findings & Data:Casein, whey, alpha-lactalbumin, beta-lactoglobulin and bovine gamma-globulin are the best known allergens in cow’s milk.
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Conclusion & Impact:It might be dangerous to administer live attenuated measles vaccine to children diagnosed with cow’s milk allergy or to children suspected of being highly sensitive to cow’s milk proteins.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Cow’s milk allergy is the most common food allergy in children. Casein, whey, alpha-lactalbumin, beta-lactoglobulin and bovine gamma-globulin are the best known allergens in cow’s milk. Herein, we present an infant who was diagnosed with severe cow’s milk allergy, followed-up with an elimination diet, and experienced a life-threatening severe anaphylaxis after live attenuated measles vaccine containing alpha-lactalbumin hydrolysate. High levels of immunoglobulin E (IgE) antibodies were determined by specific IgE analysis and the sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE) method. It might be dangerous to administer live attenuated measles vaccine to children diagnosed with cow’s milk allergy or to children suspected of being highly sensitive to cow’s milk proteins.

Özet

İnek sütü allerjisi çocuklarda en sık görülen besin allerjisidir. İnek sütü içinde bulunan kazein, whey, alfa-laktalbümin, beta-laktoglobülin ve sığır gamma-globülinleri en iyi bilinen allerjenlerdir. Burada, ağır inek sütü allerjisi tanısı alan, eliminasyon diyeti ile takip edilen, ve içerisinde alfa-laktalbümin hidrolizatı bulunan canlı atenüe kızamık aşısı uygulaması sonrasında hayatı tehdit eden ağır anafilaksi gelişen bir sütçocuğu sunulmuştur. Olguda alfa-laktalbümine karşı yüksek düzeyde immünoglobülin E (IgE) tipi antikorların varlığı spesifik IgE analizi ve sodyum dodesil sülfat poliakrilamid jel elektroforez (SDS-PAGE) yöntemi ile gösterilmiştir. İnek sütü allerjisi tanısını alan veya inek sütü proteinlerine karşı aşırı duyarlılığı olduğundan şüphelenilen çocuklara önlem alınmadan canlı atenüe kızamık aşısının yapılması tehlikeli olabilir.

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Cite This Article

UYSAL, P., ALAN, Ş., DEMİR, F., ERGE, D., YENİGÜN, A. (2018). Anaphylaxis Developoing after Measles Vaccine in an Infant with Cow’s Milk Allergy. Astım Allerji İmmünoloji, Cilt: 16 - Sayı: 3, 171–174. https://ajindex.com/articles/144435

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