SavedAdd your journal

Journals / Acta Medica Anatolia / 2015 / Cilt: 3 - Sayı: 4

Is Sodium Bicarbonate Therapy Still Up To Date?

Hüseyin KURT
Davut DEMİRKIRAN
MELİH YÜKSEL
Pages
154–160
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

These data demonstrate that SB is still popular and it will retain its popularity in the near future.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Sodium bicarbonate (SB), which has a vital role in the regulation of acid-base balance of all tissues and organs, is one of the most important buffering systems of the body.
📊
Key Findings & Data:In addition, SB treatment applied to reduce the increased acid levels in chronic kidney failure may reduce mortality.
💡
Conclusion & Impact:These data demonstrate that SB is still popular and it will retain its popularity in the near future.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Sodium bicarbonate (SB), which has a vital role in the regulation of acid-base balance of all tissues and organs, is one of the most important buffering systems of the body. SB plays an important role in the treatment of poisoning caused by numerous agents including mainly salicylate and tricyclic antidepressants. In metabolic acidosis (MA) occurred in patient with systemic and metabolic diseases, first, the primary disease should be treated and in the case of low bicarbonate levels such as diarrhea and renal tubular acidosis, missing SB should be recovered. As the kidney has an important role in acid-base balance, SB is widely used in the treatment of acute and chronic renal failure. Although there is no conclusive evidence to prevent contrast nephropathy, SB comes to the fore compared to other agents. SB is used due to MA and its effects occurring in acute renal failure. In addition, SB treatment applied to reduce the increased acid levels in chronic kidney failure may reduce mortality. While SB can be used as individualized in lactic acidosis and cardiac arrest cases, it can be used safely as a performance enhancer for athletes. SB is used widely in gastrointestinal tract diseases due to its antacid effects and its routine use is not recommended in diabetic ketoacidosis. These data demonstrate that SB is still popular and it will retain its popularity in the near future.

🔖

Cite This Article

KURT, H., DEMİRKIRAN, D., YÜKSEL, M. (2015). Is Sodium Bicarbonate Therapy Still Up To Date?. Acta Medica Anatolia, Cilt: 3 - Sayı: 4, 154–160. https://ajindex.com/articles/143730

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Cameron P, Jelinek G, Kelly AM, Murray L, Brown AFT. Textbook of Adult Emergency Medicine 3rd ed. London: Elsevier; 2009
  2. Levine M, Ruha AM. Antidepressants. In: Marx J, Walls R, Hockberger R, editors. Rosen’s Emergency Medicine. Philadelphia: Elsevier; 1981. p. 1975-81
  3. Aiken CG. History of medical understanding and misunderstanding of Acid base balance. Journal of clinical and diagnostic research: JCDR. 2013;7(9):2038-41
  4. Forsythe SM, Schmidt GA. Sodium bicarbonate for the treatment of lactic acidosis. Chest. 2000;117(1):260-7
  5. Wilson RF, Spencer AR, Tyburski JG, Dolman H, Zimmerman LH. Bicarbonate therapy in severely acidotic trauma patients increases mortality. The journal of trauma and acute care surgery. 2013;74(1):45-50; discussion 6. Gehlbach BK, Schmidt GA. Bench-to-bedside review: treating acid-base abnormalities in the intensive care unit - the role of buffers. Critical care. 2004;8(4):259- 65
  6. Aschner JL, Poland RL. Sodium bicarbonate: basically useless therapy. Pediatrics. 2008;122(4):831-5
  7. Kovesdy CP, Anderson JE, Kalantar-Zadeh K. Association of serum bicarbonate levels with mortality in patients with non-dialysis-dependent CKD. Nephrology, dialysis, transplantation: official publication of the European Dialysis and Transplant Association - European Renal Association. 2009;24(4):1232-7
  8. Gaggl M, Cejka D, Plischke M, Heinze G, Fraunschiel M, Schmidt A, et al. Effect of oral sodium bicarbonate supplementation on progression of chronic kidney disease in patients with chronic metabolic acidosis: study protocol for a randomized controlled trial (SoBic-Study). Trials. 2013;14:196
  9. Neavyn MJ, Boyer EW, Bird SB, Babu KM. Sodium acetate as a replacement for sodium bicarbonate in medical toxicology: a review. Journal of medical toxicology: official journal of the American College of Medical Toxicology. 2013;9(3):250-4
  10. Chan CY, Waring WS. Images in cardiovascular medicine. Tricyclic cardiotoxicity treated with sodium bicarbonate. Circulation. 2007;115(5):e63-4
  11. Miranda CH, Pazin-Filho A. Crack cocaine-induced cardiac conduction abnormalities are reversed by sodium bicarbonate infusion. Case reports in medicine. 2013;2013:396401
  12. Wood DM, Dargan PI, Hoffman RS. Management of cocaine-induced cardiac arrhythmias due to cardiac ion channel dysfunction. Clinical toxicology. 2009;47(1):14-23
  13. Vajner JE, 3rd, Lung D. Case files of the University of California San Francisco Medical Toxicology Fellowship: acute c