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Journals / Astım Allerji İmmünoloji / 2019 / Cilt: 17 - Sayı: 2

Hypersensitivity Reaction Due to Oral Methylprednisolone in a Patient with Nonsteroidal Anti-Inflammatory Drug-Exacerbated Respiratory Disease

Kadriye TERZİOĞLU
Raziye TÜLÜMEN ÖZTÜRK
Eda DURMUŞ
Dane EDİGER
Pages
111–114
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We present a 32-year-old patient with nonsteroidal anti-inflammatory drug-exacerbated airway disease and a hypersensitivity reaction due to methylprednisolone.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Hypersensitivity reactions caused by corticosteroids are rarely seen, despite widespread use of these medications.
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Key Findings & Data:Delayed allergic reactions may be observed after topically applied glucocorticoids, but IgE-mediated type 1 (immediate) allergic reactions, which occur after systemic application of glucocorticoids, are very rare.
💡
Conclusion & Impact:We present a 32-year-old patient with nonsteroidal anti-inflammatory drug-exacerbated airway disease and a hypersensitivity reaction due to methylprednisolone.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Hypersensitivity reactions caused by corticosteroids are rarely seen, despite widespread use of these medications. Sensitization to corticosteroids can occur through many routes such as nasal, aerosol, parenteral, oral and topical. Delayed allergic reactions may be observed after topically applied glucocorticoids, but IgE-mediated type 1 (immediate) allergic reactions, which occur after systemic application of glucocorticoids, are very rare. When case-based publications were examined, it was noticed that corticosteroid-associated IgE-mediated type 1 hypersensitivity reactions were more common in patients with nonsteroidal anti-inflammatory drug-exacerbated respiratory diseases (NERD). We present a 32-year-old patient with nonsteroidal anti-inflammatory drug-exacerbated airway disease and a hypersensitivity reaction due to methylprednisolone.

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Cite This Article

TERZİOĞLU, K., ÖZTÜRK, R. T., DURMUŞ, E., EDİGER, D. (2019). Hypersensitivity Reaction Due to Oral Methylprednisolone in a Patient with Nonsteroidal Anti-Inflammatory Drug-Exacerbated Respiratory Disease. Astım Allerji İmmünoloji, Cilt: 17 - Sayı: 2, 111–114. https://ajindex.com/articles/142837

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