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Journals / Hittite Journal of Science and Engineering / 2020 / Volume: 7 Issue: 4

Preparation, Characterization and Evaluation of Some New Amides as Antimicrobial Agents

Şükriye Çakmak(SINOP UNIVERSITY)0000-0002-2221-0098
Aysel Veysioğlu(SINOP UNIVERSITY)0000-0002-1406-5513
Pages
—
Publication Date
2020-12-31
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The results show that the some new compounds exhibit good antibacterial and antifungal activities.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The some new amide derivatives 1(a-c) and, 2d were synthesized by the two-step N-acylation of 4-nitroaniline or heterocyclic amine derivatives with acyl chlorides.
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Key Findings & Data:All of the products were determined using 13C NMR, 1H NMR, FT-IR spectroscopies and elemental analysis.
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Conclusion & Impact:The results show that the some new compounds exhibit good antibacterial and antifungal activities.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Amides · Secondary Amides · N-Acylation

Abstract

The some new amide derivatives 1(a-c) and, 2d were synthesized by the two-step N-acylation of 4-nitroaniline or heterocyclic amine derivatives with acyl chlorides. All of the products were determined using 13C NMR, 1H NMR, FT-IR spectroscopies and elemental analysis. Antimicrobial activities of the molecules were evaluated against various bacterial and fungal species. The results show that the some new compounds exhibit good antibacterial and antifungal activities.

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Cite This Article

Çakmak, Ş., Veysioğlu, A. (2020). Preparation, Characterization and Evaluation of Some New Amides as Antimicrobial Agents. Hittite Journal of Science and Engineering, Volume: 7 Issue: 4. https://doi.org/10.17350/HJSE19030000204

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