Journals / Ankara Üniversitesi Veteriner Fakültesi Dergisi / 2026 / Volume: 71 Issue: 2

Mycobacterial infection in a Nile crocodile (Crocodylus niloticus) from Türkiye

Ozan Ahlat(ANKARA UNIVERSITY, ANKARA FACULTY OF VETERINARY MEDICINE)0000-0002-2580-8140
Özgür Özöner(ANKARA UNIVERSITY, ANKARA FACULTY OF VETERINARY MEDICINE)0000-0001-7354-0655
Kürşat Filikci(HARRAN UNIVERSITY, FACULTY OF VETERINARY MEDICINE)0000-0001-9710-9480
Sevil Atalay Vural(ANKARA UNIVERSITY, ANKARA FACULTY OF VETERINARY MEDICINE)0000-0003-2111-3381
Pages
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Publication Date
2024-04-01
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Immunolabelling for both Mycobacterium bovis and anti-BCG antibodies was positive in each tissue.

📌 3 Key Takeaways

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Objective & Hypothesis:Mycobacterial infection in Nile crocodile tissues sent from a private zoo was characterized pathomorphologically and immunohistochemically in this case.
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Key Findings & Data:Macroscopically, multifocal, greyish-white areas ranging in size from 1 mm to 5 mm were seen in the lung, liver, and spleen.
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Conclusion & Impact:Immunolabelling for both Mycobacterium bovis and anti-BCG antibodies was positive in each tissue.
🔬Design:Case Report
📍Scope:Comprehensive Sample
⚙️Variables:Immunohistochemistry · Mycobacterial infection · Mycobacterium

Abstract

Mycobacterial infection in Nile crocodile tissues sent from a private zoo was characterized pathomorphologically and immunohistochemically in this case. Macroscopically, multifocal, greyish-white areas ranging in size from 1 mm to 5 mm were seen in the lung, liver, and spleen. Histologically, a large number of well-demarcated necrotic areas were seen. These areas included nuclei debris locally. Inflammatory cells along with a couple of multinucleated giant cells surrounded the necrotic cores. Numerous acid-fast bacilli were detected by Ziehl-Neelsen staining method. Immunolabelling for both Mycobacterium bovis and anti-BCG antibodies was positive in each tissue.

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Cite This Article

Ahlat, O., Özöner, Ö., Filikci, K., Vural, S. A. (2024). Mycobacterial infection in a Nile crocodile (Crocodylus niloticus) from Türkiye. Ankara Üniversitesi Veteriner Fakültesi Dergisi, Volume: 71 Issue: 2. https://doi.org/10.33988/auvfd.1139830

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References (16)

  1. Ariel E, Ladds PW, Roberts BL (1997): Mycobacteriosis in young freshwater crocodiles (Crocodylus johnstoni). Aust Vet J, 75, 831-833.
  2. Buenviaje GN, Ladds PW, Martin Y (1998): Pathology of skin diseases in crocodiles. Aust Vet J, 76, 357-363.
  3. Gcebe N, Michel AL, Hlokwe TM (2018): Non-tuberculous Mycobacterium species causing mycobacteriosis in farmed aquatic animals of South Africa. BMC Microbiol, 18, 32.
  4. Griffith AS (1928): Tuberculosis in Captive Wild Animals. J Hyg (Lond), 28, 198-218.
  5. Huchzermeyer FW (2003): Crocodiles: biology, husbandry and diseases. CABI Pub, Wallingford, Oxon, UK.
  6. Huchzermeyer FW, Huchzermeyer HF (2000): Mycobacterial infections in farmed and captive crocodiles. 109-112. In: Crocodiles. Proceedings of the 15th Working Meeting of the Crocodile Specialist Group. IUCN –The World Conservation Union, Gland, Switzerland.
  7. Kik MJ (2013): Disseminated Mycobacterium intracellulare infection in a broad-snouted caiman Caiman latirostris. Dis Aquat Organ, 107, 83-86.
  8. Lécu A, Ball R (2011): Mycobacterial infections in zoo animals: relevance, diagnosis and management. Int Zoo Yearb, 45, 183-202.
  9. Luna LG (1968). Manual of histologic staining methods of the Armed Forces Institute of Pathology, 3rd ed. Blakiston Division, McGraw-Hill, New York.
  10. Roh YS, Park H, Cho A, et al (2010): Granulomatous pneumonia in a captive freshwater crocodile (Crocodylus johnstoni) caused by Mycobacterium szulgai. J Zoo Wildl Med, 41, 550-554.
  11. Shah KK, Pritt BS, Alexander MP (2017): Histopathologic review of granulomatous inflammation. J Clin Tuberc Other Mycobact Dis, 7, 1-12.
  12. Slany M, Knotek Z, Skoric M, et al (2010): Systemic mixed infection in a brown caiman (Caiman crocodilus fuscus) caused by Mycobacterium szulgai and M. chelonae: a case report. Vet Med-Czech, 55, 91–96.
  13. Soldati G, Lu ZH, Vaughan L, et al (2004): Detection of mycobacteria and chlamydiae in granulomatous inflammation of reptiles: a retrospective study. Vet Pathol, 41, 388-397.
  14. Stacy BA, Pessier AP (2007): Host Response to infectious agents and identification of pathogens in tissue section. 257-297. In: ER Jacobson (Ed), Infectious Diseases and Pathology of Reptiles: Color Atlas and Text. CRC Press, Boca Raton, Florida.
  15. Vural SA, Alçığır ME (2010): Detection of pathomorphological and immunohistochemical findings of tuberculosis in cattle slaughtered in Ankara and its surroundings. Ankara Univ Vet Fak Derg, 57, 253-257.
  16. Zwart P (1964): Studies on Renal Pathology in Reptiles. Pathol Vet, 1, 542-556.