SavedAdd your journal

Journals / Anatolian Journal of Emergency Medicine / 2026 / Cilt: 3 Sayı: 1

Evaluation of Hypoglycaemia Associated with Antidiabetic Drugs in the Emergency Department

Acil Serviste Antidiyabetik İlaçlara Bağlı Hipogliseminin Değerlendirilmesi

Serdar Özdemir(İSTANBUL ÜMRANİYE HEALTH RESEARCH CENTER)0000-0002-6186-6110
Abdullah Algın(İSTANBUL ÜMRANİYE HEALTH RESEARCH CENTER)0000-0002-9016-9701
Hatice Şeyma Akça(İSTANBUL ÜMRANİYE HEALTH RESEARCH CENTER)0000-0003-2823-9577
Serkan Emre Eroğlu(İSTANBUL ÜMRANİYE HEALTH RESEARCH CENTER)0000-0002-3183-3713
Pages
6–8
Publication Date
2020-03-30
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Patients taking these drugs should be informed about the symptoms of hypoglycemia.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim The increased prevalence of diabetes mellistus also increases the number of diabetes-related admissions to the emergency department.
📊
Key Findings & Data:Material and Methods Patients who applied to SBU Ümraniye EAH Emergency Medicine Clinic between 01.10.2018 and 01.10.2019 with blood glucose levels below 50 mg/dL were evaluated retrospectively from hospital computer-based data system.
💡
Conclusion & Impact:Patients taking these drugs should be informed about the symptoms of hypoglycemia.
🔬Design:Klinik Araştırma
📍Scope:2018 Verileri
⚙️Variables:diyabetes mellistus · hipoglisemi · insülin

Abstract

Aim The increased prevalence of diabetes mellistus also increases the number of diabetes-related admissions to the emergency department. In this study, we aimed to evaluate the demographic data, antidiabetic drugs and clinical follow-up of hypoglycemia patients who were taking antidiabetic medications. Material and Methods Patients who applied to SBU Ümraniye EAH Emergency Medicine Clinic between 01.10.2018 and 01.10.2019 with blood glucose levels below 50 mg/dL were evaluated retrospectively from hospital computer-based data system. Patients who developed hypoglycemia due to hypoglycemic drug use were included in the study. Results Using the hospital computer-based data system, 153 patients with blood glucose levels below 50 mg/dL were identified. Seventy-five of these patients were hypoglycemic due to antidiabetic drugs. When the patients were evaluated according to the antidiabetic drugs, 47 (62.6%) patients were using insulin, 11 (14.6%) patients were using insulin and oral antidiabetic drugs, and 17 (22%) patients were using only oral antidiabetic drugs. The length of stay for the patients who were followed up and discharged in the emergency department ranged from 2 hours to 24 hours. The mean follow-up time was 9.4 hours in this patient group. One of the hospitalized patients (1.3%) died. Conclusion Hypoglycemia is a life-threatening antidiabetic drug toxicity. Patients taking these drugs should be informed about the symptoms of hypoglycemia.

Özet

Amaç Artan diyabetes mellistus prevelansı acil servise olan diyabet ilişkili başvuruları da arttırmaktadır. Biz çalışmamızda kliniğimize başvuran antidiyabetik ilaç kullanan hastalarda görülen hipoglisemi olgularının demografik verilerini, kullandıkları antidiyabetik ilaçları ve klinik takip süreçlerini değerlendirmeyi amaçladık. Gereç ve Yöntemler SBÜ Ümraniye EAH Acil Tıp Kliniğine 01.10.2018 ve 01.10.2019 tarihleri arasında başvuran hastaların hastane bilgisayar tabanlı veri sisteminden kan glikoz düzeyi 50 mg/dL altında olan hastalar retrospektif olarak tarandı. Düşük kan glikoz düzeyi ile başvuran hastaların dosyaları incelendi. Bulgular Hastane bilgisayar tabanlı veri sisteminden yararlanarak kan glikoz düzeyi 50 mg/dL altında olan 153 hasta tespit edildi. Bu hastaların 75’inin antidiyabetik ilaçlara bağlı hipoglisemik olduğu tespit edildi. Hastalar aldıkları antidiyabetik ilaçlara göre değerlendirildiğinde 47 (%62,6) hastanın insülin, 11 (%14,6) hastanın insülin ile beraberinde OAİ ve 17 (%22) hastanın ise sadece OAİ kullandığı görüldü. Acil serviste takip edilip taburcu edilen hastaların takip süreleri ise 2 saat ile 24 saat arasında değişmekteydi. Bu hasta grubunda ortalama takip süresi 9,4 saatti. Yatırılarak takip edilen hastaların birinin (%1,3) yatışı sırasında gelişen pnömoniye bağlı mortalite ile sonuçlandığı görüldü. Sonuç Hipoglisemi yaşamı tehdit eden, bir antidiyabetik ilaç toksisitesidir. Bu ilaçları kullanan hastalar hipoglisemi semptomları açısından bilgilendirilmelidir.

🔖

Cite This Article

Özdemir, S., Algın, A., Akça, H. Ş., Eroğlu, S. E. (2020). Evaluation of Hypoglycaemia Associated with Antidiabetic Drugs in the Emergency Department. Anatolian Journal of Emergency Medicine, Cilt: 3 Sayı: 1, 6–8. https://ajindex.com/articles/1361471

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (17)

  1. Satman I, Yilmaz T, Sengül A, Salman S, Salman F, Uygur S, et al. Population-based study of diabetes and risk characteristics in Turkey: results of the turkish diabetes epidemiology study (TURDEP). Diabetes Care 2002;(25):1551–6.
  2. Türk Endokronoloji ve Metabolizma Derneği. (2011) TURDEP-II Sonuçları. The web site: http://endokrin.org. tr/files/file/TURDEP_II_2011.pdf
  3. Sharma DC, Asirvatham A, Singh P. Dose modification of antidiabetic agents in patients with type 2 diabetes mellitus and heart failure. Indian J Endocrinol Metab. 2017;(21): 618–29.
  4. Whipple AO. The surgical therapy of hyperinsulinism. J Int Chir 1938; (3):237–76.
  5. Keskin Ö, Küçükardalı Y, Kalemoğlu M. Hypoglycemia at Emergency Care. Medeniyet Med J. 2004;(9):37-9
  6. Davis SN, Galassetti P, Wasserman DH, Tate D. Effects of gender on neuroendocrine and metabolic counterregulatory responses to exercise in normal man. J Clin Endocrinol Metab 2000; (85):224-230
  7. Davis SN, Cherrington AD, Goldstein RE, Jacobs J, Price L. Effefts of insulin on the counterregulatory response to equivalent hypoglycemia in normal females. Am J Physiol. 2000;(265):680–9.
  8. American Diabetes Association. “Standards of medical care in diabetes-2014.” Diabetes Care 2014;(37):14–80.
  9. International Diabetes Federation. Managing Older People with Type 2 Diabetes Global Guideline, 2013. Available at: http://www.idf.org/sites/default/files/IDFGuideline-for-older-people-T2D.pdf
  10. SM Eleff, C Borel, WR Bell, DM Long. Acute management of intracranial hemorrhage in patients receiving thrombolytic therapy. Neurosurgery 1990;(26):867–9.
  11. Colak S, Erdogan MO, Sekban H, et al. Emergency diagnosis of upper gastrointestinal bleeding by detection of haemoglobin in nasogastric aspirate. J Int Med Res. 2013; (41):1825–9
  12. Wiethop BV, Cryer PE. Alanine and terbutaline in treatment of hypoglycemia in IDDM. Diabetes Care 1993;(16):1131–6.
  13. Yu O, Azoulay L, Yin H, Filion KB, Suissa S. Sulfonylureas as initial treatment for type 2 diabetes and the risk of severe hypoglycemia. Am J Med. 2018;(131):317-22
  14. Weinstock RS, DuBose SN, Bergenstal RM, Chaytor NS, Peterson C, Olson BA, et al. Risk factors associated with severe hypoglycemia in older adults with type 1 diabetes. Diabetes Care. 2015;(39):603–10.
  15. Cryer PE, Davis SN, Shamoon H. Hypoglycemia in diabetes. Diabetes Care. 2003;(26):1902–12.
  16. American Diabetes Association. Glycemic Targets: Standards of Medical Care in Diabetes—2019. Diabetes Care 20119;(42):61-70
  17. Weinstock RS, DuBose SN, Bergenstal RM, Chaytor NS, Peterson C, Olson BA, et al. Risk factors associated with severe hypoglycemia in older adults with type 1 diabetes. Diabetes Care. 2015;(39):603–10.