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Journals / Akdeniz Tıp Dergisi / 2026 / Cilt: 3 Sayı: 3

Can a Sarcoid-like Reaction Induced by a T-cell Mediated Immune Response Mimic Breast Cancer Metastasis?

T Hücre Aracılı İmmün Yanıtla Oluşan Sarkoid Benzeri Reaksiyon Meme Kanseri Metastazını Taklit Edebilir mi?

Ahmet Ünlü(Akdeniz Üniversitesi Tıp Fakültesi, Stajyer Doktor, Antalya, Türkiye)
Önder Kırca(Memorial Hastanesi, Tıbbi Onkoloji Bölümü, Antalya, Türkiye)
İrfan Öğretmen(Memorial Hastanesi, Tıbbi Onkoloji Bölümü, Antalya, Türkiye)
Oben Duman(Memorial Hastanesi, Tıbbi Onkoloji Bölümü, Antalya, Türkiye)
Pages
215–218
Publication Date
2017-01-01
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this study, a locally advanced breast cancer case, which involved the detection of a sarcoid-like reaction, is presented with the aim of increasing awareness regarding any potential mistakes that might occur during the diagnostic PET/CT processes

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The condition involving the appearance of epithelioid non-classified granulomas, without signs of systemic sarcoidosis, is called sarcoid-like reaction.
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Key Findings & Data:These granulomas are basically seen in the tumor or the lymph nodes that drain the tumor, and cannot be distinguished from malignancy by means of imaging techniques such as PET/CT.
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Conclusion & Impact:In this study, a locally advanced breast cancer case, which involved the detection of a sarcoid-like reaction, is presented with the aim of increasing awareness regarding any potential mistakes that might occur during the diagnostic PET/CT processes
🔬Design:Makale
📍Scope:Comprehensive Sample
⚙️Variables:Sarkoid benzeri reaksiyon · Sarkoidoz · Granülom

Abstract

The condition involving the appearance of epithelioid non-classified granulomas, without signs of systemic sarcoidosis, is called sarcoid-like reaction. These granulomas are basically seen in the tumor or the lymph nodes that drain the tumor, and cannot be distinguished from malignancy by means of imaging techniques such as PET/CT. Such a condition may cause lesions to be considered as metastatic lesions in consequence of a misevaluation, and may lead to mistakes in the diagnosis, staging and treatment of the disease. In this study, a locally advanced breast cancer case, which involved the detection of a sarcoid-like reaction, is presented with the aim of increasing awareness regarding any potential mistakes that might occur during the diagnostic PET/CT processes

Özet

Sistemik sarkoidoz bulguları olmaksızın, epiteloid non-kazeifiye granülomların görülmesi halinde, bu duruma sarkoid benzeri reaksiyon adı verilmektedir. Bu granülomlar esas olarak tümör veya tümörü drene eden lenf nodlarında görülmekte ve PET/BT gibi görüntüleme yöntemleriyle de maligniteden ayırt edilememektedir. Bu durum, lezyonların yanlışlıkla metastaz olarak değerlendirilmesine yol açabilmekte ve hastalığın tanı, evreleme ve tedavisinde ciddi hatalara yol açarak telafisi mümkün olmayan sonuçlar doğurabilmektedir. Bu yüzden bu çalışmada; supraklavikular, paratrakeal ve subkarinal lenf nodu tutulumunun gözlendiği sarkoid reaksiyonlu, lokal ileri evre meme kanseri bir olgu sunulmuş ve PET/BT ile teşhiste oluşabilecek yanılgılar adına farkındalık yaratılmaya çalışılmıştır

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Cite This Article

Ünlü, A., Kırca, Ö., Öğretmen, İ., Duman, O. (2017). Can a Sarcoid-like Reaction Induced by a T-cell Mediated Immune Response Mimic Breast Cancer Metastasis?. Akdeniz Tıp Dergisi, Cilt: 3 Sayı: 3, 215–218. https://ajindex.com/articles/1359634

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