Journals / Acta Medica Nicomedia / 2024 / Cilt: 7 Sayı: 3

Evaluation of Insulin Resistance and Metabolic Syndrome Components in Patients with Seborrheic Dermatitis

Seboreik Dermatitli Hastalarda İnsülin Direnci ve Metabolik Sendrom Parametrelerinin Değerlendirilmesi

Rabia Öztaş Kara(SAKARYA ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, DERMATOLOJİ ANABİLİM DALI)0000-0003-1828-5844
Bahar Sevimli Dikicier(SAKARYA ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, DERMATOLOJİ ANABİLİM DALI)0000-0002-1912-3946
Berna Solak(SAKARYA ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, DERMATOLOJİ ANABİLİM DALI)0000-0002-1683-2421
Büşra Aydın(SAKARYA ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, DERMATOLOJİ ANABİLİM DALI)0000-0002-2385-7723
Pages
283–287
Publication Date
2024-10-27
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: SD patients may have an increased risk of metabolic syndrome development and may have higher inflammation and insulin resistance status compared with controls.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Seborrheic dermatitis (SD) is a common inflammatory skin disorder.
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Key Findings & Data:Methods: Sixty-six patients with seborrheic dermatitis and 52 healthy controls were enrolled.
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Conclusion & Impact:Conclusion: SD patients may have an increased risk of metabolic syndrome development and may have higher inflammation and insulin resistance status compared with controls.
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Metabolik sendrom · Seboreik dermatit · İnsülin direnci

Abstract

Objective: Seborrheic dermatitis (SD) is a common inflammatory skin disorder. There is scarce data regarding SD and metabolic syndrome. We aimed to investigate the prevalence of metabolic syndrome in patients with seborrheic dermatitis. Methods: Sixty-six patients with seborrheic dermatitis and 52 healthy controls were enrolled. Subjects’ height, weight, waist circumference, smoking status, and comorbidities were recorded. Blood pressure, fasting blood glucose, triglyceride, HDL, total cholesterol, and insulin levels were measured. Seborrheic dermatitis area and severity index (SASI) score, body mass index (BMI), and Homeostatic Model Assessment-Insulin Resistance (HOMA-IR) were calculated. The presence of metabolic syndrome was evaluated. Results: BMI, waist circumference, glucose, HOMA-IR, and C-reactive protein (C-RP) were significantly higher in the SD group. The prevalence of hypertension and type II diabetes was significantly higher in the SD group than in the controls. There was no difference between the patient and control groups regarding metabolic syndrome. However, the duration of SD was significantly higher in SD with metabolic syndrome than those of SD without metabolic syndrome. There were no significant differences in age and SASI score between seborrheic dermatitis patients with and without metabolic syndrome. Conclusion: SD patients may have an increased risk of metabolic syndrome development and may have higher inflammation and insulin resistance status compared with controls.

Özet

Amaç: Seboreik dermatit (SD) yaygın görülen inflamatuar bir deri hastalığıdır. SD ve metabolik sendrom ile ilgili az veri vardır. Bu çalışmada seboreik dermatitli hastalarda metabolik sendrom prevalansını araştırmayı amaçladık. Yöntem: Çalışmaya seboreik dermatit tanılı 66 hasta ve 52 sağlıklı kontrol dahil edildi. Olguların boyları, kiloları, bel çevreleri, sigara içme durumları ve ek hastalıkları kaydedildi. Kan basıncı, açlık kan şekeri, trigliserit, HDL ve total kolesterol, insülin düzeyleri ölçüldü. Seboreik dermatit alan ve şiddet indeksi (SASI) skoru, vücut kitle indeksi (VKİ) ve Homeostatik Model Değerlendirme-İnsülin Direnci (HOMA-IR) hesaplandı. Metabolik sendrom varlığı değerlendirildi. Bulgular: VKİ, bel çevresi, glukoz, HOMA-IR ve C-Reaktif Protein (C-RP) SD grubunda anlamlı olarak yüksekti. Hipertansiyon ve tip II diyabet prevalansı SD grubunda kontrol grubuna göre anlamlı derecede yüksekti. Metabolik sendrom varlığı açısından gruplar arasında fark izlenmedi Ancak metabolik sendromlu SD'de SD süresi, metabolik sendromu olmayan SD'ye göre anlamlı olarak daha yüksekti. Metabolik sendromu olan ve olmayan seboreik dermatitli hastalar arasında yaş ve SASI skoru açısından anlamlı fark yoktu. Sonuç: SD hastalarında metabolik sendrom gelişme riski artmış olabilir. Seboreik dermatit (SD) hastalarında kontrollere kıyasla daha yüksek inflamasyon ve insülin direnci durumu olabileceğini belirledik.

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Cite This Article

Kara, R. Ö., Dikicier, B. S., Solak, B., Aydın, B. (2024). Evaluation of Insulin Resistance and Metabolic Syndrome Components in Patients with Seborrheic Dermatitis. Acta Medica Nicomedia, Cilt: 7 Sayı: 3, 283–287. https://doi.org/10.53446/actamednicomedia.1457017

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