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Journals / Acta Medica Nicomedia / 2026 / Cilt: 8 Sayı: 1

Research Trends on TNF-Alpha Polymorphisms and Psoriasis: A Bibliometric Analysis

TNF-Alfa Polimorfizmleri ve Sedef Hastalığı Üzerine Araştırma Eğilimleri: Bibliyometrik Bir Analiz

Yasemin Adali(PAMUKKALE ÜNİVERSİTESİ)0000-0002-6314-4816
Veli Kaan Aydın(PAMUKKALE ÜNİVERSİTESİ)0000-0001-8371-6239
Yasemin Berberoğlu(PAMUKKALE ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0003-4226-674X
Aylin Koseler(PAMUKKALE ÜNİVERSİTESİ)0000-0003-4832-0436
Pages
23–29
Publication Date
2025-02-28
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Future researchers may find the results of this study useful in their work, and it may present new avenues for investigating TNF-alpha polymorphisms and psoriasis.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: The immune system is the source of the inflammatory, persistent skin condition known as psoriasis.
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Key Findings & Data:Methods: The Web of Science database was searched on March 26, 2024, with the terms “resilienc*” in the title and “tumo$r necrosis factor* or TNF or tumo$r necrosis factor*” and “polymorphism* or variant* or variation* or SNP*” and “psoriasis OR psoriatic*” in the topic.
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Conclusion & Impact:Conclusion: Future researchers may find the results of this study useful in their work, and it may present new avenues for investigating TNF-alpha polymorphisms and psoriasis.
🔬Design:Araştırma Makalesi
📍Scope:2024 Verileri
⚙️Variables:TNF-alfa polimorfizmi · sedef hastalığı · bibliyometrik analiz

Abstract

Purpose: The immune system is the source of the inflammatory, persistent skin condition known as psoriasis. Despite recent major advancements in the pathology of psoriasis, no bibliometric investigation associating TNF-Alpha polymorphisms to psoriasis has been conducted. The objective of this study was to better understand the development trend and boundaries of the area by using bibliometrics to assess the focal point and research overview of TNF-Alpha Polymorphisms and Psoriasis. Methods: The Web of Science database was searched on March 26, 2024, with the terms “resilienc*” in the title and “tumo$r necrosis factor* or TNF or tumo$r necrosis factor*” and “polymorphism* or variant* or variation* or SNP*” and “psoriasis OR psoriatic*” in the topic. There were 400 documents extracted in all. Visualizations created by web-r.org were made using web-based R analytics developed with bibliometric analysis. Results: Since 2012, research on the relationship between psoriasis and TNF-Alpha polymorphisms has increased significantly. The research that received the most attention was published in Dermatology and the British Journal, with Nair RP receiving the most citations. China, the United States, and Italy were the most productive nations. "Association," "Rheumatoid Arthritis," and "Susceptibility" appeared most frequently in the KeyWordPlus analysis. Conclusion: Future researchers may find the results of this study useful in their work, and it may present new avenues for investigating TNF-alpha polymorphisms and psoriasis.

Özet

Amaç: Bağışıklık sistemi, sedef hastalığı olarak bilinen iltihaplı, kalıcı cilt rahatsızlığının kaynağıdır. Sedef hastalığının patolojisinde son zamanlarda kaydedilen önemli gelişmelere rağmen, TNF-Alfa polimorfizmlerini sedef hastalığıyla ilişkilendiren hiçbir bibliyometrik araştırma yürütülmemiştir. Bu çalışmanın amacı, bibliyometrik kullanarak TNF-Alfa Polimorfizmleri ve Sedef Hastalığı'nın odak noktasını ve araştırma genel bakışını değerlendirerek alanın gelişim eğilimini ve sınırlarını daha iyi anlamaktır. Yöntemler: Web of Science veritabanı 26 Mart 2024'te, başlıkta "resilienc*" terimleri ve konu başlığında "tumor necrosis factor* or TNF or tumo$r necrosis factor*" ve "polymorphism* or variant* or vary* or SNP*" ve "psoriasis OR psoriatic*" terimleriyle arandı. Toplamda 400 belge çıkarıldı. Web-r.org tarafından oluşturulan görselleştirmeler bibliyometrik analiziyle geliştirilen web tabanlı R analizi ile yapıldı. Bulgular: 2012'den bu yana, sedef hastalığı ve TNF-Alfa polimorfizmleri arasındaki ilişki üzerine yapılan araştırmalar önemli ölçüde arttı. En fazla ilgi gören araştırma Dermatology ve British Journal'da yayınlandı ve Nair RP en fazla atıfı aldı. En üretken ülkeler Çin, Amerika Birleşik Devletleri ve İtalya oldu. "Association", "Romatoid Arthritis" ve "Susceptibility" KeyWordPlus analizinde en sık görülen ifadelerdir. Sonuç: Gelecekteki araştırmacılar bu çalışmanın sonuçlarını çalışmalarında faydalı bulabilir ve TNF-alfa polimorfizmleri ve sedef hastalığını araştırmak için yeni yollar sunabilir.

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Cite This Article

Adali, Y., Aydın, V. K., Berberoğlu, Y., Koseler, A. (2025). Research Trends on TNF-Alpha Polymorphisms and Psoriasis: A Bibliometric Analysis. Acta Medica Nicomedia, Cilt: 8 Sayı: 1, 23–29. https://doi.org/10.53446/actamednicomedia.1554862

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