Journals / Acta Medica Nicomedia / 2026 / Cilt: 8 Sayı: 2

Genetic Disease Behind Obesity And Its Nutritional Treatment; Prader-Willi Syndrome

Obezitenin Arkasindaki Genetik Hastalik Ve Beslenme Tedavisi; Prader-Willi Sendromu

Gökcen Doğan(LOKMAN HEKİM ÜNİVERSİTESİ, SAĞLIK BİLİMLERİ FAKÜLTESİ)0000-0001-8690-1341
Aylin Bülbül(ANKARA ÜNİVERSİTESİ, SAĞLIK BİLİMLERİ ENSTİTÜSÜ)0000-0002-4754-0149
Pages
244–250
Publication Date
2025-06-30
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

To prevent obesity in Prader-Willi Syndrome, it is necessary to continue nutritional therapy for life.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Obesity is a health problem that reduces the quality of life and is associated with many chronic diseases.
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Key Findings & Data:Due to the increased levels of the hormone ghrelin, a feeling of satiety cannot occur.
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Conclusion & Impact:To prevent obesity in Prader-Willi Syndrome, it is necessary to continue nutritional therapy for life.
🔬Design:Derleme
📍Scope:Comprehensive Sample
⚙️Variables:Prader willi sendromu · obezite · tıbbi beslenme tedavisi

Abstract

Obesity is a health problem that reduces the quality of life and is associated with many chronic diseases. There are many physiological, socio-cultural, psychological, and genetic causes of obesity. Prader-Willi Syndrome is the most common genetic disease associated with obesity. Prader-Willi Syndrome is characterized by severe anorexia in infancy and hyperphagia in childhood. Hyperphagia, which begins in childhood, is the basis of obesity in Prader-Willi Syndrome. Hyperphagia in Prader-Willi Syndrome occurs as a result of the imbalance in fasting-satiety metabolism. Due to the increased levels of the hormone ghrelin, a feeling of satiety cannot occur. The treatments applied for Prader-Willi Syndrome aim to prevent obesity. It is stated that the most effective treatment method is medical nutrition therapy. To prevent obesity in Prader-Willi Syndrome, it is necessary to continue nutritional therapy for life.

Özet

Obezite yaşam kalitesini azaltan, birçok kronik hastalıkla ilişkilendirilen bir sağlık sorunudur. Obezitenin fizyolojik, sosyo-kültürel, psikolojik, genetik birçok sebebi bulunmaktadır. Prader Willi Sendromu (PWS) obezite ile ilişkilendirilen en yaygın genetik hastalıktır. PWS bebeklik döneminde şiddetli anoreksi, çocukluk döneminde hiperfaji ile karakterizedir. Çocukluk dönemi itibariyle başlayan hiperfaji PWS’de obezite oluşumunun temelidir. PWS’deki hiperfaji açlık-tokluk metabolizmasındaki dengenin bozulması sonucu oluşmaktadır. Artan grelin hormonu seviyeleri sebebiyle tokluk hissi oluşamamaktadır. PWS’de uygulanan tedavilerin amacı obezitenin önlenmesine yöneliktir. En etkili tedavi yönteminin tıbbi beslenme tedavisi olduğu belirtilmektedir. PWS’de obezitein önüne geçilebilmesi için yaşam boyu diyet tedavisine devam edilmesi gerekmektedir.

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Cite This Article

Doğan, G., Bülbül, A. (2025). Genetic Disease Behind Obesity And Its Nutritional Treatment; Prader-Willi Syndrome. Acta Medica Nicomedia, Cilt: 8 Sayı: 2, 244–250. https://doi.org/10.53446/actamednicomedia.1474539

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References (3)

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