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Journals / Hitit Medical Journal / 2026 / Cilt: 6 Sayı: 1

Can HCG MoM Ratio Predict Preeclampsia?

HCG Oranı Preeklempsiyi Predikte Edermi?

Betül Tokgöz(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA ETLİK ZÜBEYDE HANIM KADIN HASTALIKLARI SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0003-0202-4981
Gizem Kızılboğa(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA ETLİK ZÜBEYDE HANIM KADIN HASTALIKLARI SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0003-3696-1287
Seval Yılmaz Ergani(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA ETLİK ZÜBEYDE HANIM KADIN HASTALIKLARI SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0002-7017-8854
Aykut Kından(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA ETLİK ZÜBEYDE HANIM KADIN HASTALIKLARI SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0002-0962-1036
Mehmet Obut(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA ETLİK ZÜBEYDE HANIM KADIN HASTALIKLARI SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0002-6925-4784
Levent Dereli(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA ETLİK ZÜBEYDE HANIM KADIN HASTALIKLARI SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0002-9602-9099
Kadriye Yakut Yücel(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA ETLİK ZÜBEYDE HANIM KADIN HASTALIKLARI SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0003-3182-4312
Erkan Sağlam(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA ETLİK ZÜBEYDE HANIM KADIN HASTALIKLARI SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0001-5600-5597
Fahri Burçin Fıratlıgil(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA ETLİK ZÜBEYDE HANIM KADIN HASTALIKLARI SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0002-4499-3492
Sadullah Özkan(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA ETLİK ZÜBEYDE HANIM KADIN HASTALIKLARI SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0003-2432-1434
Onur Kaya(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA ETLİK ZÜBEYDE HANIM KADIN HASTALIKLARI SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0001-7497-1422
Caner Çakır(UNIVERSITY OF HEALTH SCIENCES, ANKARA ETLİK ZÜBEYDE HANIM HEALTH RESEARCH CENTER FOR GYNECOLOGICAL DISEASES)0000-0003-2559-9104
Şevki Çelen(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA ETLİK ZÜBEYDE HANIM KADIN HASTALIKLARI SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0001-7033-3474
Ali Çağlar(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA ETLİK ZÜBEYDE HANIM KADIN HASTALIKLARI SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0002-7022-3029
Yaprak Ustun(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA ETLİK ZÜBEYDE HANIM KADIN HASTALIKLARI SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0002-1011-3848
Pages
21–27
Publication Date
2024-02-26
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Rating the MoM values of β-HCG, a biochemical marker used in screening tests for chromosomal anomaly, may predict preeclampsia in the later weeks of pregnancy.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: To predict preeclampsia by the ratio of the HCG MoM value in the first and second trimester screening tests.
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Key Findings & Data:Material and Methods: The HCG-MoM values of 136 pregnant women with preeclampsia and 222 normatensive pregnant women used for first and second-trimester screening tests were proportioned , and the difference between the groups was examined.
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Conclusion & Impact:Conclusion: Rating the MoM values of β-HCG, a biochemical marker used in screening tests for chromosomal anomaly, may predict preeclampsia in the later weeks of pregnancy.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Preeklempsi · HCG MoM · Tarama Testleri

Abstract

Objective: To predict preeclampsia by the ratio of the HCG MoM value in the first and second trimester screening tests. Material and Methods: The HCG-MoM values of 136 pregnant women with preeclampsia and 222 normatensive pregnant women used for first and second-trimester screening tests were proportioned , and the difference between the groups was examined. Numeric variables are expressed as mean ± standard deviation, median (minimum – maximum), and categorical variables as n (%). Results: HCG MoM values were not different between the two groups and were within the accepted international values. The ratio of the free HCG MoM value in the first trimester to the intact HCG MoM value in the second trimester was significantly higher in the control group (1.06) than in the study group (0.99) (p=0.02). Conclusion: Rating the MoM values of β-HCG, a biochemical marker used in screening tests for chromosomal anomaly, may predict preeclampsia in the later weeks of pregnancy.

Özet

Amaç: Birinci ve ikinci trimester tarama testlerindeki HCG MoM değerinin oranına göre preeklampsiyi öngörmek. Gereç ve Yöntemler: 136 preeklampsili gebe ile 222 normal tansiyonlu gebenin birinci ve ikinci trimester tarama testleri için kullandıkları HCG-MoM değerleri oranlanarak gruplar arasındaki fark incelendi. Sayısal değişkenler ortalama ± standart sapma, medyan (minimum – maksimum), kategorik değişkenler ise n (%) olarak ifade edilmiştir. Bulgular: İki grup arasında HCG MoM değerleri arasında fark izlenmedi ve kabul edilen uluslararası değerler içerisindeydi . Birinci trimesterdeki serbest HCG MoM değerinin, ikinci trimesterdeki intakt HCG MoM değerine oranı kontrol grubunda (1,06) çalışma grubuna göre (0,99) anlamlı olarak yüksekti (p=0,02). Sonuç: Kromozomal anomali tarama testlerinde kullanılan biyokimyasal bir belirteç olan β-HCG'nin MoM değerlerinin derecelendirilmesi, gebeliğin ileri haftalarında preeklampsiyi öngörebilir.

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Cite This Article

Tokgöz, B., Kızılboğa, G., Ergani, S. Y., Kından, A., Obut, M., Dereli, L., Yücel, K. Y., Sağlam, E., Fıratlıgil, F. B., Özkan, S., Kaya, O., Çakır, C., Çelen, Ş., Çağlar, A., Ustun, Y. (2024). Can HCG MoM Ratio Predict Preeclampsia?. Hitit Medical Journal, Cilt: 6 Sayı: 1, 21–27. https://doi.org/10.52827/hititmedj.1298037

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