Journals / Hitit Medical Journal / 2026 / Cilt: 8 Sayı: 3

Does Illness Perception Influence Treatment Outcomes in Erectile Dysfunction? an Observational Study on Depressive Symptoms and Short-Term Treatment Response

Hastalık Algısı Erektil Disfonksiyonda Tedavi Sonuçlarını Etkiler mi? Depresif Semptomlar ve Kısa Dönem Tedavi Yanıtı Üzerine Gözlemsel Bir Çalışma

Nazım Furkan Günay(İskilip Atıf Hoca Devlet Hastanesi)0000-0002-2205-5825
Caglar Dizdaroglu(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, İSTANBUL HASEKİ SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0002-8589-129X
Mücahit Gelmiş(AĞLIK BİLİMLERİ ÜNİVERSİTESİ, İSTANBUL GAZİOSMAPAŞA SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0002-8061-6950
Feyzi Sinan Erdal(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, İSTANBUL HASEKİ SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0002-3248-7664
Faruk Özgör(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, İSTANBUL HASEKİ SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0001-8712-7458
Pages
522–532
Publication Date
2026-10-14
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Incorporating illness perception assessment into ED management may support a stratified biopsychosocial approach.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: To investigate the relationship between illness perceptions, depressive symptoms, and erectile function (EF) in men with erectile dysfunction (ED) and to evaluate longitudinal changes following treatment.
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Key Findings & Data:Materials and Methods: Patients with ED (IIEF-5 ≤21) were enrolled at a tertiary urology outpatient clinic between June and October 2025.
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Conclusion & Impact:Incorporating illness perception assessment into ED management may support a stratified biopsychosocial approach.
🔬Design:Survey & Empirical Study
📍Scope:2025 Verileri
⚙️Variables:Depresyon · Erektil disfonksiyon · Hastalık algısı

Abstract

Objective: To investigate the relationship between illness perceptions, depressive symptoms, and erectile function (EF) in men with erectile dysfunction (ED) and to evaluate longitudinal changes following treatment. Materials and Methods: Patients with ED (IIEF-5 ≤21) were enrolled at a tertiary urology outpatient clinic between June and October 2025. Participants completed the International Index of Erectile Function-5 (IIEF-5), Patient Health Questionnaire-9 (PHQ-9), and Brief Illness Perception Questionnaire (B-IPQ) at baseline and at 1 and 3 months. All patients received lifestyle counseling and phosphodiesterase type-5 inhibitor therapy. Associations were analyzed using correlation and multivariable linear regression analyses. Results: A total of 120 patients completed follow-up. More negative illness perceptions were significantly associated with higher depressive symptom severity and worse ED severity (p < 0.05). B-IPQ scores increased progressively across categories of both depressive symptoms and ED severity. Multivariable analysis showed that education level, IIEF-5 score, and PHQ-9 score were independently associated with illness perception scores (all p<0.05). EF and illness perception improved significantly during follow-up in patients with no or mild-to-moderate depressive symptoms, whereas patients with moderately severe depressive symptoms demonstrated no significant improvement. Conclusion: Illness perception is an important cognitive and emotional factor associated with ED severity, depressive symptoms, and treatment response. Incorporating illness perception assessment into ED management may support a stratified biopsychosocial approach.

Özet

Amaç: Erektil disfonksiyon (ED) sorunu yaşayan erkeklerde hastalık algısı, depresif belirtiler ve erektil fonksiyon (EF) arasındaki ilişkiyi araştırmak ve tedaviyi takiben meydana gelen uzun vadeli değişiklikleri değerlendirmek. Gereç ve Yöntemler: Haziran ile Ekim 2025 tarihleri arasında üçüncü basamak üroloji polikliniğine başvuran ve ED tanısı konmuş (IIEF-5 ≤21) hastalar çalışmaya dahil edildi. Katılımcılar, başlangıçta, 1. ay ve 3. ayda Uluslararası Erektil Fonksiyon Endeksi-5 (IIEF-5), Hasta Sağlığı Anketi-9 (PHQ-9) ve Kısa Hastalık Algısı Anketi’ni (B-IPQ) doldurdu. Tüm hastalar yaşam tarzı danışmanlığı ve fosfodiesteraz tip 5 inhibitörü tedavisi aldı. İlişkiler, korelasyon ve çok değişkenli doğrusal regresyon analizleri kullanılarak incelendi. Bulgular: Toplam 120 hasta takip sürecini tamamladı. Daha olumsuz hastalık algısı, daha yüksek depresif semptom şiddeti ve daha kötü ED şiddeti ile anlamlı bir şekilde ilişkiliydi (p<0,05). B-IPQ puanları, hem depresif semptomlar hem de ED şiddeti arttıkça, kademeli olarak artmıştır. Çok değişkenli analiz, eğitim düzeyi, IIEF-5 puanı ve PHQ-9 puanının hastalık algısı puanlarıyla bağımsız olarak ilişkili olduğunu göstermiştir (tümü p<0,05). Takip süresince, depresif semptomu olmayan veya hafif-orta derecede olan hastalarda EF ve hastalık algısı önemli ölçüde iyileşirken, orta-şiddetli olan hastalarda önemli bir iyileşme görülmedi. Sonuç: Hastalık algısı, ED vakalarının ciddiyeti, depresif belirtiler ve tedaviye yanıt ile bağlantılı önemli bir bilişsel-duygusal faktördür. Hastalık algısı değerlendirmesinin ED yönetimine dahil edilmesi, kademelendirilmiş bir biyopsikososyal yaklaşımı destekleyebilir.

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Cite This Article

Günay, N. F., Dizdaroglu, C., Gelmiş, M., Erdal, F. S., Özgör, F. (2026). Does Illness Perception Influence Treatment Outcomes in Erectile Dysfunction? an Observational Study on Depressive Symptoms and Short-Term Treatment Response. Hitit Medical Journal, Cilt: 8 Sayı: 3, 522–532. https://doi.org/10.52827/hititmedj.1927973

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