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Journals / Bakırköy Tıp Dergisi / 2010 / Cilt: 6 - Sayı: 1

Lamivudin ve adefovir direncine bağlı HBV DNA artışının AFP seviyesiyle ilişkisi

Close association of AFP level with HBV-DNA increase caused by lamivudine and adefovir resistance

Özcan KARAMAN
Mehmet ÇÖLBAY
İhsan USLAN
Gürsel ACARTÜRK
Pages
39–41
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The patient had a prompt improvement after adefovir and entacavir treatment, respectively.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Marked elevations in serum alpha fetoprotein (AFP) levels are highly suspicious for hepatocellular carcinoma and should prompt an exten- sive diagnosis.
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Key Findings & Data:We report a case of chronic hepatitis B where episodes of marked elevations in serum AFP levels occurred, after viral bre- akthrough and acute exacerbation of hepatitis following development of lamivudine and adefovir resistance.
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Conclusion & Impact:The patient had a prompt improvement after adefovir and entacavir treatment, respectively.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Marked elevations in serum alpha fetoprotein (AFP) levels are highly suspicious for hepatocellular carcinoma and should prompt an exten- sive diagnosis. We report a case of chronic hepatitis B where episodes of marked elevations in serum AFP levels occurred, after viral bre- akthrough and acute exacerbation of hepatitis following development of lamivudine and adefovir resistance. The patient had a prompt improvement after adefovir and entacavir treatment, respectively.

Özet

Serum alfa fetoprotein (AFP) seviyelerindeki belirgin yükselme hepatosellüler karsinoma tanısında oldukça anlamlı olup ileri araştırmayı gerektirir. Lamivudin ve adefovir direnci sonrası viral atak ve akut hepatit alevlenmesi ile serum AFP seviyelerinde belirgin artış gösteren kronik hepatit B vakasını sunacağız. Hasta adefovir ve entacavir tedavisi sonrası belirgin bir şekilde düzeldi.

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Cite This Article

KARAMAN, Ö., ÇÖLBAY, M., USLAN, İ., ACARTÜRK, G. (2010). Lamivudin ve adefovir direncine bağlı HBV DNA artışının AFP seviyesiyle ilişkisi. Bakırköy Tıp Dergisi, Cilt: 6 - Sayı: 1, 39–41. https://ajindex.com/articles/132893

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