Journals / Bakırköy Tıp Dergisi / 2018 / Cilt: 14 - Sayı: 4

Investigation of Risk Factors in Patients with Silent Posterior Cerebral Artery Infarctions

Sessiz Posterior Serebral Arter Enfarktlı Hastalarda Risk Faktörlerinin Araştırılması

Pages
421–426
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Determination of all these risk factors, particularly introduction of changeable, treatable risk factors, taking attention of physician and community to this subject will lead to the removal of very important distances to avoid diseases which increase mortality and morbidity such as cerebrovascular diseases.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Silent brain infarcts are a term used for no symptoms and findings clinically but have evidence in cranial radiologic imagings or autopsy materials.
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Key Findings & Data:Materials and Methods: A total of 30 patients, 23 men and 7 women, who had no previous neurological findings but who had a silent PCA infarction on cranial imaging, were included in this study.
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Conclusion & Impact:Determination of all these risk factors, particularly introduction of changeable, treatable risk factors, taking attention of physician and community to this subject will lead to the removal of very important distances to avoid diseases which increase mortality and morbidity such as cerebrovascular diseases.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Silent brain infarcts are a term used for no symptoms and findings clinically but have evidence in cranial radiologic imagings or autopsy materials. The development of cranial imaging techniques in recent years has facilitated the detection of silent brain infarcts. The aim of this study is to investigate the risk factors in patients with silent posterior cerebral artery (PCA) infarct and compare them with patients with symptomatic cerebral artery infarctions. Materials and Methods: A total of 30 patients, 23 men and 7 women, who had no previous neurological findings but who had a silent PCA infarction on cranial imaging, were included in this study. A total of 87 patients, 46 male and 41 female, who were evaluated as symptomatic cerebral infarction according to anamnesis, clinical and radiological findings and treated in our clinic during the same period, were randomized into the control group. Results: Both groups were compared in terms of risk factors. While age, smoking, oral contraceptive and/or hormone preparation use, stroke history in family, hyperlipidemia, diabetes mellitus, heart valve disease, myocardial infarction, hypertension, transient ischemic attack history, pathologic electrocardiogram findings, heart failure and atrial fibrillation were not different in both groups, alcohol consumption and gender considered as risk factors were found to be different between the groups. Conclusion: In this study, risk factors for silent posterior cerebral infarction and symptomatic cerebral infarction were found to be similar except for alcohol and gender. Determination of all these risk factors, particularly introduction of changeable, treatable risk factors, taking attention of physician and community to this subject will lead to the removal of very important distances to avoid diseases which increase mortality and morbidity such as cerebrovascular diseases.

Özet

Amaç: Sessiz beyin enfarktları klinik olarak bulgusu ve semptomu olmayan ancak kraniyal radyolojik görüntülemelerde veya otopsi materyallerinde gösterilen vasküler hasarlar için kullanılan bir terimdir. Son yıllarda gelişen kraniyal görüntüleme tekniklerinin gelişimi ile sessiz beyin enfarktlarının saptanması kolaylaşmıştır. Bu çalışmanın amacı sessiz posterior serebral arter (PSA) enfarktlı hastalarda risk faktörlerinin araştırılması ve semptomatik serebral arter enfarktlı hastalarla karşılaştırılmasıdır. Gereç ve Yöntemler: Çalışmaya daha önceden nörolojik bulgusu olmayan ancak kraniyal görüntülemelerinde sessiz PSA enfarktı saptanan 23’ü erkek, 7’si kadın toplam 30 hasta dahil edildi. Kontrol grubuna anamnez, klinik ve radyolojik bulguları ile semptomatik serebral enfarkt olarak değerlendirilen ve aynı süre içinde kliniğimizde yatarak tedavi gören 46’sı erkek, 41’i kadın toplam 87 hasta randomize olarak dahil edildi. Bulgular: Her iki grup risk faktörleri açısından karşılaştırıldı. Yaş, sigara kullanımı, oral kontraseptif ve/veya hormon preparatı kullanımı, ailede inme anamnezi, hiperlipidemi, diyabetes mellitus, kalp kapak hastalığı, miyokard enfarktüsü, hipertansiyon, geçici iskemik atak öyküsü, patolojik elektrokardiyografi (EKG) bulgusu, kalp yetmezliği ve atriyal fibrilasyon sessiz enfarkt grubunda, kontrol grubuna göre farklı bulunmazken, alkol kullanımı ve cinsiyet risk faktörü olarak ele alındığında gruplar arasında anlamlı fark bulunmuştur. Sonuç: Bu çalışmada sessiz posterior serebral enfarktlı ve semptomatik serebral enfarktlı hastalarda risk faktörleri alkol kullanımı ve cinsiyet dışında benzer bulunmuştur. Tüm bu risk faktörlerinin belirlenmesi, özellikle değiştirilebilir, tedavi edilebilir risk faktörlerinin ortaya konması, hekim ve toplumun dikkatinin bu konuya çekilmesi, serebrovasküler hastalık gibi mortalite ve morbiditeyi artıran hastalıkların önlenmesinde çok önemli mesafeler alınmasına imkan tanıyacaktır.

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Cite This Article

TEKESİN, A., TUNÇ, A., YAĞIZ, O. (2018). Investigation of Risk Factors in Patients with Silent Posterior Cerebral Artery Infarctions. Bakırköy Tıp Dergisi, Cilt: 14 - Sayı: 4, 421–426. https://ajindex.com/articles/132166

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References (14)

  1. Bernick C, Kuller L, Dulberg C, Longstreth WT Jr, Monolio T, Beauchamp N, et al. Silent MRI infarcts and the risk of future stroke: the cardiovascular health study. Neurology 2001;57:1222-9.
  2. Corea F, Henon H, Pasquier F, Leys D. Silent infarcts in stroke patients: patient characteristics and effect on 2-year outcome. J Neurol 2001;248:271-8.
  3. Uekita K, Funayama N, Nishiura T, Makiguchi N, Sakamoto N, Aoyama H, et al. Prevalence of cervical and cerebral atherosclerosis and silent brain infarction in patients with multivessel coronary artery disease. J Cardiol 2001;38:13-20.
  4. Petersen P, Madsen EB, Brun B, Pedersen F, Glydensted C, Baysen G. Silent cerebral infarction in chronic atrial fibrillation. Stroke 1987;18:1098-100.
  5. Czechowsky D, Hill MD. Neurological outcome and quality of life after stroke due to vertebral artery dissection. Cerebrovasc Dis 2002;13:192- Caplan LR, Tettenborn B. Vertebrobasilar occlusive disease: review of selected aspects. Posterior circulation embolism. Cerebrovasc Dis 1992;2:320-6.
  6. Castaigne P, Lhermitte F, Gautier JC, Escourole R, Derouesne C, Agopıan PD, et al. Arterial occlusions in the vertebral-basilar system. Brain 1973;96:133-54.
  7. Pessin MS, Lathi ES, Cohen MB, Kwan ES, Hedges TR 3rd, Caplan LR. Clinical features and mechanism of occipital infarction. Ann Neurol 1987;21:290-9.
  8. Wolf PA, Belanger AJ, D’Agostino RB. Management of Risk Factors. Neurologic Clinics 1992;10:177-91.
  9. Harmsen P, Tsipogianni A, Wilhelmsen L. Stroke incidence rates were unchanged, while fatality rates declined, during 1971-1987 in Göteborg, Sweden. Stroke 1992;23:1410-5.
  10. Thompson DW, Furlan AJ. Clinical Epidemiology of Stroke. Neurologic Clinics 1996;14:309-15.
  11. Herderschee D, Hijdra A, Algra A, Kaudstaal PJ, Kapplelle LJ, van Gijn J. Silent stroke in patients with transient ischemic attack or minor ischemic stroke. The Dutch TIA Trial Study Group. Stroke 1992;23:1220-4.
  12. Shintani S, Shiigai T, Arinami T. Silent lacunar infarction on magnetic resonance imaging (MRI): risk factors. J Neurology Sci 1998;18;160:82-6. Koto A. Diagnosis of silent cerebral infarction. Rinsho Shinkeigaku 1996;36:1373-5.
  13. Gross CR, Kase CS, Mohr JP, Cunningham SC, Baker WE. Stroke in South Alabama: Incidence and Diagnostic Features-A Population Based Study. Stroke 1994;15:249-55.
  14. Liu LH, Chia LG. The effects of hypertension, diabetes mellitus, atrial fibrillation, transient ischemic attack and smoking on stroke in Chinese people. Chung Hua I Hsueh Tsa Chih (Taipei) 1991;47:110-5. S