Journals / Bakırköy Tıp Dergisi / 2005 / Cilt: 1 - Sayı: 3

Vitamin A and caroten levels in preterm newborns with respiratory distress syndrome

Respiratuar distres sendromlu preterm yenidoğanlarda vitamin A ve karoten düzeyleri

Pages
95–98
DOI
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⚡ TL;DR(Too Long; Didn't Read)

The level in infants with RDS was 48.8±41.96 mcg/dl, whereas it was found to be 45.7±30 mcg/dl in the control group.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The aim of this study is to compare the vitamin A and carotene levels in preterm infants with or without respiratory distress syndrome.
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Key Findings & Data:Material and Methods: Vitamin A and carotene levels in 40 preterm AGA (appropriate for gestational age) infants, 20 of which had respiratory distress syndrome and the other 20 infants with no respiratory distress syndrome were compared.
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Conclusion & Impact:The level in infants with RDS was 48.8±41.96 mcg/dl, whereas it was found to be 45.7±30 mcg/dl in the control group.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Karotenoidler · Solunum güçlüğü sendromu · yenidoğan

Abstract

Objective: The aim of this study is to compare the vitamin A and carotene levels in preterm infants with or without respiratory distress syndrome. Material and Methods: Vitamin A and carotene levels in 40 preterm AGA (appropriate for gestational age) infants, 20 of which had respiratory distress syndrome and the other 20 infants with no respiratory distress syndrome were compared. Results: Vitamin A level in infants at 28-32 gestation week who had RDS was 7.33±3.36 mcg /dl, and in the healthy infants (control group) the level was 9.83±4.62 mcg /dl. There was no significant statistical difference in spite of a mathematical difference. The carotene level in infants with RDS was 28.5 ±11.46 mcg /dl, and in the control group was 49±29.12 mcg/dl. Vitamin A level in infants at 33-36 gestation week with RDS was 4.32±3.58 mcg /dl, whereas in the control group, the level was found to be 7.98±4.46 mcg/dl. In these cases a significant difference existed. Carotene level when compared between the groups revealed no significant difference. The level in infants with RDS was 48.8±41.96 mcg/dl, whereas it was found to be 45.7±30 mcg/dl in the control group. There was no correlation between the carotene level, vitamin A level and the birth weight, height, head circumference and sex. Conclusion: In our study as all the cases had low vitamin A levels, early vitamin A supplementation was recommended to be administered to the premature infants.

Özet

Respiratuar distres sendromlu preterm yenidoğanlarda vitamin A ve karoten düzeyleri Amaç: Çalışmamızda solunum sıkıntısı olan ve olmayan premature yenidoğanlarda A vitamin düzeylerini belirlemeyi amaçladık. Gereç ve Yöntem: Yenidoğan servisimize yatırılan 20 respiratuar distress sendromlu (çalışma grubu) ve 20 solunum sıkıntısı olmayan (kontrol grubu) preterm yenidoğanda yaşamlarının ikinci gününde serum A vitamini ve karoten düzeyleri bakıldı.Bulgular: Gestasyon haftası 28-32 olan çalışma grubu bebeklerde A vitamin 7.33±3.36 mcg/dl ve kontrol grubu bebeklerde 9.83± 4.62 mcg /di idi. Aralarında matematiksel fark olmasına rağmen istatiksel fark yoktu. Karoten düzeyi aynı gruplarda sırasıyla 28.5± 11.46 mcg /di ve 49±29.12 mcg/dl idi. Gestasyon haftası 33-36 olan çalışma grubu bebeklerde A vitamin 4.32± 3.58 mcg/dl ve kontrol grubu bebeklerde 7.98± 4.46 mcg/dl olup, aralarında anlamlı fark vardı. Karoten düzeyi aynı gruplar arasında sırasıyla 48.8±41.96 mcg/dl ve 45.7± 30 mcg/dl idi. Doğum ağırlığı, boy, baş çevresi ve cinsiyetin A vitamin ve karoten düzeyi ile ilişkisi saptanmadı.Sonuç: Çalışmamızdaki tüm vakaların A vitamin seviyesi çok düşük bulunduğundan, solunum sorunu olan ve olmayan tüm prematürelerde, erken vitamin a desteği yapılmasının uygun olacağı düşünüldü.

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Cite This Article

YOLAR, L., KARATEKİN, G., NUHOĞLU, A. (2005). Vitamin A and caroten levels in preterm newborns with respiratory distress syndrome. Bakırköy Tıp Dergisi, Cilt: 1 - Sayı: 3, 95–98. https://ajindex.com/articles/131770

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References (14)

  1. Davis MJ, Rosenfeld NW. Bronchopulmonary Dysplasia. In: MacDonald MG, Mullett DM, Seshia MM (eds): Avery’s Neonatology - Pathophysiology & Management of the Newborn. 6th ed. Philedelphia, Lippincot Williams & Wilkins, 2005, s 578- 599
  2. Greenough A, Milner A. Chronic lung disease. In: Rennie MJ (ed ): Robertons Textbook of Neonatology. 4th ed, Philedelphia, Elsevier Churchill Livingstone, 2005, s 554- 572 3. Coutsoudis A, Adhikari M, Coovadia HM. Serum vitamin A (retinol) concentrations and association with respiratory disease in premature infants. J Trop Pediatr 1995; 41: 230-233
  3. Shenai JP, Rush MG, Stahlman MT, Chytil F. Plasma retinol binding protein response to vitamin A administration in infants susceptible to bronchopulmonary dysplasia. J Pediatr 1990; 116: 607-614
  4. Zachman RD. Role of vitamin A in lung devolepment. J Nutr 1995; 125: 1634S-1638S
  5. Ballard JL, Khourg JC, Wedig K, Wang L, Eilers- Walsman BL, Lipp R. New Ballard score, expanded to include extremly premature infants. J Pediatr 1991; 119: 417-423
  6. Oliver RW, Kafwembe EM. A new spectrophotometric assay for the determination of vitamin A and related compounds in serum. Int J Vitam Nutr Res 1992; 62: 221-227
  7. Hustead VA, Gutcher GR, Anderson SA, Zachman RD. Relation of vitamin A status to lung disease in preterm infant. J Pediatr 1984; 105: 610-615
  8. Chan V, Greenough A, Cheeseman P, Gamsu HR. Vitamin A status in preterm and term infants at birth. J Perinat Med 1993; 21: 59-62
  9. Chan V, Greenough A, Cheeseman P, Gamsu HR. Vitamin A levels at birth of high risk preterm infants. J Perinat Med 1993; 21: 147-151
  10. Tammela O, Aitola M, Ikonen S. Cord blood concentrations of vitamin A in preterm infants. Early Hum Dev 1999; 56: 39-47
  11. Schulpis KH, Michalakakou K, Gavrili S, et al. Maternal-neonatal retinol and alpha-tocopherol serum concentrations in Greeks and Albanians. Acta Paediatr 2004; 93: 1075-1080
  12. Shenai JP. Vitamin A supplementation in very low birth weight neonates: Rationale and Evidence. Pediatrics 1999; 104: 1369-1374
  13. Spears K, Cheney C, Zerzan J. Low plasma retinol concentrations increase the risk of developing bronchopulmonary dysplasia and long-term respiratory disability in very-low-birth-weight infants. Am J Clin Nutr 2004; 80: 1589-1594
  14. Ambalavanan N, Tyson JE, Kennedy KA, Hansen NI, Vohr BR, Wright LL, Carlo WA, National Institute of Child Health and Human Development Nenatal Research Network. Vitamin A supplementation for extremel