Journals / Bakırköy Tıp Dergisi / 2010 / Cilt: 6 - Sayı: 3

An uncommon food intoxication treated in intensive care: Botulism

Yoğun bakımda takip edilen nadir görülen besin zehirlenmesi: Botilismus

Pages
125–128
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Here, we reported a 21 years old a male patient with the diagnosis of botulinum intoxication, successfully treated in our intensive care unit.

📌 3 Key Takeaways

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Objective & Hypothesis:Botulism is a rare neuroparalytic disease caused by a neurotoxin produced by the spore-producing bacterium Clostridium botulinum, an obligate anaerobe bacteria is found commonly in the environment.
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Key Findings & Data:This toxin binds to the receptors of the axon membrane of the motor neurons, preventing the release of acetylcholine in the neuromuscular junction, causing şaccid paralysis.
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Conclusion & Impact:Here, we reported a 21 years old a male patient with the diagnosis of botulinum intoxication, successfully treated in our intensive care unit.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Botulism is a rare neuroparalytic disease caused by a neurotoxin produced by the spore-producing bacterium Clostridium botulinum, an obligate anaerobe bacteria is found commonly in the environment. This toxin binds to the receptors of the axon membrane of the motor neurons, preventing the release of acetylcholine in the neuromuscular junction, causing şaccid paralysis. First findings are diplopia and nistagmus; resulting from the weakness of small extraokuler muscles. Bulber paralysis, respiratuary paralysis, cardiac arrest and at the end death can be seen. Treatment includes meticulous intensive care that includes mechanical ventilation, if necessary, and administration of antitoxin. Here, we reported a 21 years old a male patient with the diagnosis of botulinum intoxication, successfully treated in our intensive care unit.

Özet

Botulismus, doğada yaygın olarak bulunan zorunlu anaerob bakteri, Clostridium botilinum tarafından oluşturulan nörotoksine bağlı olarak meydana gelen nöroparalitik nadir bir hastalıktır. Bu toksin motor nöronların akson membranlarındaki reseptörlere bağlanıp nöromuskuler bileşkede asetilkolin salınımını önleyerek şask paralizilere yol açmaktadır. İlk bulgular, ekstraokuler kaslar gibi küçük kasların tutulumuna bağlı olarak ortaya çıkan diplopi ve nistagmustur. Bulber paralizi, respiratuar paralizi, kardiyak arrest ve sonunda ölüm görülebilir. Tedavi, gerektiğinde mekanik ventilasyon desteği, ve antitoksinin uygulanmasını içeren dikkatli bir yoğun bakım desteğini gerektirmektedir. Bu yazıda, botilismus zehirlenmesi tanısıyla yoğun bakım ünitemizde başarı ile tedavi edilen 21 yaşında bir erkek olgu sunulmuştur.

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Cite This Article

ALTUN, D., ÇUKUROVA, Z., EREN, G., POLAT, Y., AŞAR, S., HERGÜNSEL, O., YAYLA, V. A. (2010). An uncommon food intoxication treated in intensive care: Botulism. Bakırköy Tıp Dergisi, Cilt: 6 - Sayı: 3, 125–128. https://ajindex.com/articles/130769

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