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Journals / Namık Kemal Tıp Dergisi / 2019 / Cilt: 7 Sayı: 1

Assessment of Methotrexate Efficacy in The Treatment of Ectopic Pregnancy

Mehmet Obut(DİYARBAKIR GAZİ YAŞARGİL SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0002-6925-4784
Hanifi Bademkıran(DİYARBAKIR GAZİ YAŞARGİL SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0002-9350-582X
Sedat Akgöl(DİYARBAKIR GAZİ YAŞARGİL SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0001-8609-3049
Bekir Kahveci(DİYARBAKIR GAZİ YAŞARGİL SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0002-8729-1669
İhsan Bağlı(DİYARBAKIR GAZİ YAŞARGİL SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0002-3195-9164
Süleyman Cemil Oğlak(DİYARBAKIR GAZİ YAŞARGİL SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0001-7634-3008
Mehmet Şukru Budak(DİYARBAKIR GAZİ YAŞARGİL SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0001-7328-4188
Pages
25–30
Publication Date
2019-04-22
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The overall success rate of the medical treatment was 90.7% for a second dose of MTX.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:ABSTRACT Objective : Our aim in this study was to assess efficacy of single-dose methotrexate (MTX) as medical treatment for ectopic pregnancy (EP) by evaluating the results of patients given this treatment.
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Key Findings & Data:Materials and Methods: Between September 2016 and August 2017, the treatment outcomes of EP cases treated with MTX at Gazi Yaşargil Training and Research Hospital of Health Sciences University were evaluated retrospectively.
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Conclusion & Impact:The overall success rate of the medical treatment was 90.7% for a second dose of MTX.
🔬Design:Araştırma Makalesi
📍Scope:2016 Verileri
⚙️Variables:Ectopic pregnancy · medical treatment · methotrexate

Özet

ABSTRACT Objective : Our aim in this study was to assess efficacy of single-dose methotrexate (MTX) as medical treatment for ectopic pregnancy (EP) by evaluating the results of patients given this treatment. Materials and Methods: Between September 2016 and August 2017, the treatment outcomes of EP cases treated with MTX at Gazi Yaşargil Training and Research Hospital of Health Sciences University were evaluated retrospectively. Results: In total, 126 cases treated for EP were evaluated and 65 cases were included in the study. In cases administered a single dose of MTX, the success rate was 80%, the failure rate was 13.8%, and the emergency surgery rate was 6.2%. The overall success rate of the medical treatment was 90.7% for a second dose of MTX. An unsuccessful result was considered as less than a 15% reduction in the beta-human chorionic gonadotropin (β-hCG) level between 4 and 7 days after single dose MTX administration. In all cases, the rate of emergency surgery after treatment was 9.3%. Conclusion : In our study, success rates in patients with EP treated with MTX were 80% after a single dose and as high as 90.7% when a second dose was added.

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Cite This Article

Obut, M., Bademkıran, H., Akgöl, S., Kahveci, B., Bağlı, İ., Oğlak, S. C., Budak, M. Ş., *, M. O. (2019). Assessment of Methotrexate Efficacy in The Treatment of Ectopic Pregnancy. Namık Kemal Tıp Dergisi, Cilt: 7 Sayı: 1, 25–30. https://ajindex.com/articles/1295089

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