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Dergiler / Namık Kemal Tıp Dergisi / 2026 / Cilt: 7 Sayı: 1

Assessment of Methotrexate Efficacy in The Treatment of Ectopic Pregnancy

Mehmet Obut(DİYARBAKIR GAZİ YAŞARGİL SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0002-6925-4784
Hanifi Bademkıran(DİYARBAKIR GAZİ YAŞARGİL SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0002-9350-582X
Sedat Akgöl(DİYARBAKIR GAZİ YAŞARGİL SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0001-8609-3049
Bekir Kahveci(DİYARBAKIR GAZİ YAŞARGİL SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0002-8729-1669
İhsan Bağlı(DİYARBAKIR GAZİ YAŞARGİL SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0002-3195-9164
Süleyman Cemil Oğlak(DİYARBAKIR GAZİ YAŞARGİL SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0001-7634-3008
Mehmet Şukru Budak(DİYARBAKIR GAZİ YAŞARGİL SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0001-7328-4188
Sayfa
25–30
Yayın Tarihi
2019-04-22
DOI
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Conclusion : In our study, success rates in patients with EP treated with MTX were 80% after a single dose and as high as 90.7% when a second dose was added.

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Amaç & Hipotez:ABSTRACT Objective : Our aim in this study was to assess efficacy of single-dose methotrexate (MTX) as medical treatment for ectopic pregnancy (EP) by evaluating the results of patients given this treatment.
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Temel Bulgular & Veri:Materials and Methods: Between September 2016 and August 2017, the treatment outcomes of EP cases treated with MTX at Gazi Yaşargil Training and Research Hospital of Health Sciences University were evaluated retrospectively.
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Sonuç & Katkı:Conclusion : In our study, success rates in patients with EP treated with MTX were 80% after a single dose and as high as 90.7% when a second dose was added.
🔬Tür:Araştırma Makalesi
📍Kapsam:2016 Verileri
⚙️Değişkenler:Ectopic pregnancy · medical treatment · methotrexate

Özet

ABSTRACT Objective : Our aim in this study was to assess efficacy of single-dose methotrexate (MTX) as medical treatment for ectopic pregnancy (EP) by evaluating the results of patients given this treatment. Materials and Methods: Between September 2016 and August 2017, the treatment outcomes of EP cases treated with MTX at Gazi Yaşargil Training and Research Hospital of Health Sciences University were evaluated retrospectively. Results: In total, 126 cases treated for EP were evaluated and 65 cases were included in the study. In cases administered a single dose of MTX, the success rate was 80%, the failure rate was 13.8%, and the emergency surgery rate was 6.2%. The overall success rate of the medical treatment was 90.7% for a second dose of MTX. An unsuccessful result was considered as less than a 15% reduction in the beta-human chorionic gonadotropin (β-hCG) level between 4 and 7 days after single dose MTX administration. In all cases, the rate of emergency surgery after treatment was 9.3%. Conclusion : In our study, success rates in patients with EP treated with MTX were 80% after a single dose and as high as 90.7% when a second dose was added.

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Bu Makaleye Atıf Yap

Obut, M., Bademkıran, H., Akgöl, S., Kahveci, B., Bağlı, İ., Oğlak, S. C., Budak, M. Ş. (2019). Assessment of Methotrexate Efficacy in The Treatment of Ectopic Pregnancy. Namık Kemal Tıp Dergisi, Cilt: 7 Sayı: 1, 25–30. https://ajindex.com/articles/1295089

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Kaynakça (25)

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