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Journals / Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi / 2026 / Volume: 11 Issue: 2

Age-Related Diffusion Changes in The Corpus Vitreum And Aqueous Humor of The Ocular Bulb

Bulbus Okulinin Korpus Vitreumu ve Hümör Aközünde Yaşa Bağlı Difüzyon Değişiklikleri

Bünyamin Güney(MSKÜ Tıp Fakültesi Radyoloji AD)0000-0002-0853-4184
Ferda Bacakszılar Sarı(MUĞLA SITKI KOÇMAN ÜNİVERSİTESİ, TIP FAKÜLTESİ, TIP PR.)0000-0002-6293-9481
Emrah Doğan(MUĞLA SITKI KOÇMAN ÜNİVERSİTESİ, TIP FAKÜLTESİ, TIP PR.)0000-0002-9446-2294
Pages
—
Publication Date
2024-08-31
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Changes in the diffusion values of the eye in VH and HA due to aging show that the biochemical contents of both structures change with aging.

📌 3 Key Takeaways

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Objective & Hypothesis:The bulbus oculi consists of two main fluid-containing anatomical structures: the aqueous humor (AH) at the anterior and the vitreous humor (VH) at the posterior.
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Key Findings & Data:VH and HA diffusion values were calculated in the eyes of a total of 128 patients divided into 8 different groups according to their ages.
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Conclusion & Impact:Changes in the diffusion values of the eye in VH and HA due to aging show that the biochemical contents of both structures change with aging.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:3 Tesla · ADC · Diffusion MRI

Abstract

The bulbus oculi consists of two main fluid-containing anatomical structures: the aqueous humor (AH) at the anterior and the vitreous humor (VH) at the posterior. In this study, we investigated the diffusion changes that occur due to aging in these two structures with different biochemical contents using magnetic resonance imaging. VH and HA diffusion values were calculated in the eyes of a total of 128 patients divided into 8 different groups according to their ages. The results obtained were compared according to age, gender and right-left distinction. There was no statistically significant difference in the diffusion values obtained for both VH and HA between genders (p=0.397, p=0.383) and between right and left eyes (p>0.568, p>0.717). However, the first decade age group had the lowest diffusion values for both structures (p<0.001). Changes in the diffusion values of the eye in VH and HA due to aging show that the biochemical contents of both structures change with aging.

Özet

Bulbus okuli, anteriorda hümör aköz (HA) ve posteriorda vitröz hümör (VH) olmak üzere iki ana sıvı içerikli anatomik yapıdan oluşur. Bu çalışmada, farklı biyokimyasal içeriğe sahip bu iki yapıda yaşlanmaya bağlı olarak oluşan difüzyon değişikliklerini manyetik rezonans görüntüleme kullanarak araştırdık Yaşlarına göre 8 farklı gruba ayrılan toplam 128 hastanın gözünde VH ve HA difüzyon değerleri hesaplandı. Elde edilen sonuçlar yaş, cinsiyet ve sağ-sol ayrımına göre karşılaştırıldı. Hem VH hem de HA için elde edilen difüzyon değerlerinde cinsiyetler arasında (p=0.397, p=0.383) ve sağ ve sol gözler arasında (p>0.568, p>0.717) istatistiksel olarak anlamlı fark saptanmadı. Ancak ilk dekat yaş grubu her iki yapı için de en düşük difüzyon değerlerine sahipti (p<0.001). Yaşlanmaya bağlı olarak gözün VH ve HA’de difüzyon değerlerinde meydana gelen değişiklikler, her iki yapının biyokimyasal içeriğinin yaşlanmayla birlikte değiştiğini göstermektedir.

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Cite This Article

Güney, B., Sarı, F. B., Doğan, E. (2024). Age-Related Diffusion Changes in The Corpus Vitreum And Aqueous Humor of The Ocular Bulb. Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi, Volume: 11 Issue: 2. https://doi.org/10.47572/muskutd.1482491

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