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Journals / Meandros Medical And Dental Journal / 2026 / Volume: 3 Issue: 1

Paget's Disease of Bone; A Case Report and Review of the Literature

KEMİĞİN PAGET HASTALIĞI; Bir olgu ve literatürün gözden geçirilmesi

Taşkın Şentürk
Nihat Özgel
Hulki Meltem Sönmez
Pages
—
Publication Date
2002-04-01
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We report a patient with Paget's disease and discuss features of this disorder which is of importance in the elderly population

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Paget's disease of bone is a common condition characterized by bone pain, deformity, pathological fracture, neurologic disorders and an increased incidence of osteosarcoma in the elderly people.
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Key Findings & Data:Histopathologically the disease is characterized by markedly increased osteoclast formation and bone resorption followed by excessive new bone formation.
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Conclusion & Impact:We report a patient with Paget's disease and discuss features of this disorder which is of importance in the elderly population
🔬Design:Article
📍Scope:Comprehensive Sample
⚙️Variables:Paget's disease · bone symptoms

Abstract

Paget's disease of bone is a common condition characterized by bone pain, deformity, pathological fracture, neurologic disorders and an increased incidence of osteosarcoma in the elderly people. Genetic factors play a role in the pathogenesis of Paget's disease but the molecular basis of the disease remains unclear. Histopathologically the disease is characterized by markedly increased osteoclast formation and bone resorption followed by excessive new bone formation. Frequently the diagnosis is made as an incidental finding on X-ray, or it is considered because of an unexpected elevation in serum alkaline phosphatase. Paget's disease can reduce both function and mobility, and can be associated with psychological problems. Therefore, quality of life may be reduced in patients with Paget's disease. We report a patient with Paget's disease and discuss features of this disorder which is of importance in the elderly population

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Cite This Article

Şentürk, T., Özgel, N., Sönmez, H. M. (2002). Paget's Disease of Bone; A Case Report and Review of the Literature. Meandros Medical And Dental Journal, Volume: 3 Issue: 1. https://ajindex.com/articles/1291450

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References (17)

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