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Journals / Bakırköy Tıp Dergisi / 2015 / Cilt: 11 - Sayı: 3

Can general anesthesia trigger the activation of latent measles infection?

Can General Anesthesia Trigger The Activation of Latent Measles Infection?

ERDEM DİNÇ
Ayça SARI
Çetin OKUYAZ
Nurcan DORUK
Pages
134–136
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Nevertheless particularly in patients with suspicious vaccination and previous measles infection, it may not be possible to enlighten the actual pathophysiology

📌 3 Key Takeaways

🎯
Objective & Hypothesis:We present a patient who was diagnosed as subacute sclerosing panencephalitis (SSPE) following a cataract surgery under general anesthesia and we discuss the possible physiopathological mechanisms in this disease.
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Key Findings & Data:An 11 years old boy presenting with right traumatic cataract and underwent an uncomplicated cataract surgery under general anesthesia.
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Conclusion & Impact:Nevertheless particularly in patients with suspicious vaccination and previous measles infection, it may not be possible to enlighten the actual pathophysiology
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

We present a patient who was diagnosed as subacute sclerosing panencephalitis (SSPE) following a cataract surgery under general anesthesia and we discuss the possible physiopathological mechanisms in this disease. An 11 years old boy presenting with right traumatic cataract and underwent an uncomplicated cataract surgery under general anesthesia. Ten days following the surgery, the patient developed dysartria, cerebellar dysfunction and mental deterioration. The patient was diagnosed as SSPE with the clinical and laboratory findings, and treatment was started. Considering the pathophysiology of SSPE and effect of general anesthesia on the immune system, we think either a latent SSPE infection was activated or subclinically present infection started a rapid progression following an operation under general anesthesia. Nevertheless particularly in patients with suspicious vaccination and previous measles infection, it may not be possible to enlighten the actual pathophysiology

Özet

Genel anestezi altında travmatik katarakt cerrahisi geçiren sonrasında subakut sklerozan panensefalit (SSPE) tanısı konan hastada olası fizyopatolojik mekanizmaları tartışmak. On bir yaşındaki erkek hastaya sağ travmatik katarakt nedeniyle genel anestezi altında komplikasyonsuz katarakt cerrahisi uygulandı. Cerrahiden 10 gün sonra hastada dizartri, serebellar disfonksiyon ve mental yavaşlama gelişti. Klinik ve laboratuvar bulguları ile hastaya SSPE tanısı kondu ve tedaviye başlandı. Genel anestezinin immün sistem üzerindeki muhtemel olumsuz etkileri ve SSPE’nin patofizyolojisi göz önüne alındığında, genel anestezi ile hastamızda önceden varolan subklinik enfeksiyonda hızlı bir ilerlemenin ya da latent SSPE’nin aktivasyonunun tetiklendiğini düşünmekteyiz. Özellikle aşılama durumunun veya kızamık öyküsünün şüpheli olduğu çocuk hastalarda patofizyolojinin tam olarak aydınlatılabilmesi mümkün olmayabilir

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Cite This Article

DİNÇ, E., SARI, A., OKUYAZ, Ç., DORUK, N. (2015). Can general anesthesia trigger the activation of latent measles infection?. Bakırköy Tıp Dergisi, Cilt: 11 - Sayı: 3, 134–136. https://ajindex.com/articles/128911

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