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Journals / Bakırköy Tıp Dergisi / 2015 / Cilt: 11 - Sayı: 4

Agranulocytosis due to propylthiouracil treatment: a case report

Propiltiourasil Kullanımına Bağlı Agranülositoz: Olgu Sunumu

Tevfik SABUNCU
Mehmet Ali ERREN
Fatih KURNAZ
Ayşe Nur TORUN
Umut SERT BATUK
Pages
167–169
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We present a case of hyperthyroidism due to Graves disease who was admitted with the typical signs of agranulocytosis at two months after the initiation of therapy and treated successfully with granulocyte colony stimulating factor.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Propylthiouracil (PTU) is a commonly used anti-thyroid drug in the treatment of hyperthyroidism due to Graves disease.
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Key Findings & Data:Life-threatening complications such as agranulocytosis may occur during the treatment of PTU.
💡
Conclusion & Impact:We present a case of hyperthyroidism due to Graves disease who was admitted with the typical signs of agranulocytosis at two months after the initiation of therapy and treated successfully with granulocyte colony stimulating factor.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Propylthiouracil (PTU) is a commonly used anti-thyroid drug in the treatment of hyperthyroidism due to Graves disease. Life-threatening complications such as agranulocytosis may occur during the treatment of PTU. We present a case of hyperthyroidism due to Graves disease who was admitted with the typical signs of agranulocytosis at two months after the initiation of therapy and treated successfully with granulocyte colony stimulating factor.

Özet

Propiltiourasil (PTU) Graves hastalığına bağlı hipertiroidinin tedavisinde sıklıkla kullanılan antitiroid bir ilaçtır. PTU kullanımı sırasında nadir de olsa agranülositoz gibi hayatı tehdit eden komplikasyonlar ortaya çıkabilmektedir. Graves hastalığına bağlı hipertiroidi nedeniyle propiltiourasil tedavisi başlandıktan 2 ay sonra tipik agranülositoz belirtileri ile başvurup tanı koyduğumuz ve granülosit koloni stimüle edici faktör kullanımı ile başarıyla tedavi ettiğimiz bir olguyu sunuyoruz.

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Cite This Article

SABUNCU, T., ERREN, M. A., KURNAZ, F., TORUN, A. N., BATUK, U. S. (2015). Agranulocytosis due to propylthiouracil treatment: a case report. Bakırköy Tıp Dergisi, Cilt: 11 - Sayı: 4, 167–169. https://ajindex.com/articles/128881

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