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Journals / MANTAR DERGİSİ / 2026 / Cilt: 16 Sayı: 1

Screening of Antibacterial Effects of Various Trichoderma Isolates on Some Human and Plant Pathogenic Bacteria Under in vitro Conditions

Çeşitli Trichoderma İzolatlarının Bazı İnsan ve Bitki Patojeni Bakteriler Üzerindeki Antibakteriyel Etkisinin in vitro Koşullarda Taranması

Kemal Karaca(EGE ÜNİVERSİTESİ)0000-0003-2193-2854
Melise İphar(EGE ÜNİVERSİTESİ)0009-0006-2190-5601
Rengin Eltem(EGE UNIVERSITY, FACULTY OF ENGINEERING, DEPARTMENT OF BIOENGINEERING, BIOENGINEERING PR.)0000-0002-0642-7676
Pages
34–41
Publication Date
2025-04-30
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Our study shows that antibacterial metabolites obtained from Trichoderma isolates have the potential to control of pathogens.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The increasing global antibacterial resistance constitutes a major public health issue.
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Key Findings & Data:In particular, fungi of the Trichoderma Pers. species play a significant role in this biological control.
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Conclusion & Impact:Our study shows that antibacterial metabolites obtained from Trichoderma isolates have the potential to control of pathogens.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Trichoderma · Antibakteriyel etki · Fitopatojen

Abstract

The increasing global antibacterial resistance constitutes a major public health issue. Consequently, there is a substantial growing need for effective new antibacterial compounds for the treatment and prevention of bacterial infections. This is where the concept of biological control comes into play. In particular, fungi of the Trichoderma Pers. species play a significant role in this biological control. Investigating the effects of biological control agents such as Trichoderma spp. in combating pathogens and controlling diseases in both agricultural production and human infections represents an important area of research. The aim of this study is to determine the antibacterial effects of metabolites from previously isolated local and unique Trichoderma isolates against some plant and human pathogenic bacteria under in vitro conditions. Among the Trichoderma isolates (n=30) tested, 11 showed antibacterial activity against Escherichia coli, 6 against Staphylococcus aureus, 18 against Pseudomonas aeruginosa, 5 against Pseudomonas cichorii, and 20 against P. syringae pv. tomato. Our study shows that antibacterial metabolites obtained from Trichoderma isolates have the potential to control of pathogens.

Özet

Küresel çapta antibakteriyel direncin giderek artması büyük bir halk sağlığı sorununu oluşturmaktadır. Dolayısıyla bakteriyel enfeksiyonların tedavi edilmesi ve önlenmesi için etkili yeni antibakteriyel bileşiklere duyulan ihtiyaç büyük ölçüde artmaktadır. Bu noktada devreye biyolojik mücadele kavramı girmektedir. Özellikle Trichoderma Pers. türü funguslar bu biyolojik mücadelede büyük rol oynamaktadırlar. Tarımsal üretimde ve insan enfeksiyonlarında patojenlerle mücadele ile hastalık kontrolünü sağlamada Trichoderma spp. gibi biyolojik mücadele etmenlerinin etkilerinin incelenmesi önemli bir alanı oluşturmaktadır. Çalışmanın amacı bazı bitki ve insan patojeni bakterilere karşı daha önceki çalışmalar kapsamında izole edilmiş yerel ve özgün Trichoderma izolatlarının metabolitlerinin in vitro koşullarda antibakteriyel etkilerinin belirlenmesidir. Trichoderma izolatları (n=30) arasından antibakteriyel etkiye sahip Escherichia coli’ye karşı 11, Staphylococcus aureus’a karşı 6, Pseudomonas aeruginosa’ya karşı 18, Pseudomonas cichorii’ye karşı 5 ve P. syringae pv. tomato’ya karşı 20 adet izolat tespit edilmiştir. Çalışmamız Trichoderma izolatlarından elde edilecek antibakteriyel metabolitlerin patojenler ile mücadelede potansiyelinin olduğunu göstermektedir.

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Cite This Article

Karaca, K., İphar, M., Eltem, R. (2025). Screening of Antibacterial Effects of Various Trichoderma Isolates on Some Human and Plant Pathogenic Bacteria Under in vitro Conditions. MANTAR DERGİSİ, Cilt: 16 Sayı: 1, 34–41. https://doi.org/10.30708/mantar.1606682

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