Journals / Bakırköy Tıp Dergisi / 2019 / Cilt: 15 - Sayı: 4

Vitamin B12 Deficiency in Children with Tension-Type Headache: Case-control Study

Gerilim Tipi Baş Ağrısı Olan Çocuklarda Vitamin B12 Eksikliği: Olgu-kontrol Çalışması

Pages
388–392
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Keywords: Headache, children, vitamin B12

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: We aimed to determine the frequency of vitamin B12 deficiency in children with tension-type headache and to investigate the relationship between tension-type headache and vitamin B12 deficiency.
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Key Findings & Data:Methods: The children diagnosed with tension-type headache between June 1, 2018 and December 31, 2018 in the pediatric neurology clinic were included in the study.
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Conclusion & Impact:Keywords: Headache, children, vitamin B12
🔬Design:Research Article
📍Scope:2018 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: We aimed to determine the frequency of vitamin B12 deficiency in children with tension-type headache and to investigate the relationship between tension-type headache and vitamin B12 deficiency. Methods: The children diagnosed with tension-type headache between June 1, 2018 and December 31, 2018 in the pediatric neurology clinic were included in the study. Children with chronic disease, receiving dietary supplementation or any medication were excluded from the study. Demographic characteristics, complete blood count, the levels of serum vitamin B12, folate, homocysteine and urine methylmalonic acid were recorded. The control group consisted of children without an acute or chronic disease and who did not use dietary supplements or medications. Results: A total of 155 children were participated in the study including 76 children (57 girls, 19 boys) with tension-type headache and 79 children (51 girls, 28 boys) in the control group. The mean serum vitamin B12 level was 210.6±104 pg/mL (43-534 pg/mL) in patients with tension-type headache and 260.6±109 pg/mL in the control group (104-712 pg/mL). There was a statistically significant difference between the two groups in terms of the level of vitamin B12 (p=0.005). Forty-six patients (61%) with tension-type headache and 30 children (38%) in the control group had vitamin B12 deficiency. There was a statistically significant difference between the two groups in terms of vitamin B12 deficiency (p=0.032). Conclusion: We found vitamin B12 deficiency in more than half of the children with tension-type headache. We conclude that it is important to evaluate children with tension-type headache in terms of vitamin B12 deficiency. Keywords: Headache, children, vitamin B12

Özet

Amaç: Gerilim tipi baş ağrısı olan çocuklarda vitamin B12 eksikliği sıklığını belirleyerek gerilim tipi baş ağrısı ile vitamin B12 eksikliği arasındaki ilişkiyi incelemeyi amaçladık. Yöntemler: Çocuk nörolojisi polikliniğinde 1 Haziran 2018 ile 31 Aralık 2018 tarihleri arasında gerilim tipi baş ağrısı tanısı alan çocuklar çalışmaya dahil edildi. Bilinen kronik hastalığı olan, diyet takviyesi alan veya herhangi bir ilaç kullanan çocuklar çalışmadan çıkarıldı. Hastaların demografik özellikleri, ilk başvurudaki tam kan sayımı, serum vitamin B12, folat, homosistein değerleri ile idrar metilmalonik asit düzeyleri kaydedildi. Kontrol grubu akut veya kronik bir hastalığı olmayan, diyet takviyesi veya herhangi bir ilaç kullanmayan çocuklardan oluşturuldu. Bulgular: Gerilim tipi baş ağrısı tanılı 76 hasta (57 kız, 19 erkek) ve kontrol grubunda 79 çocuk (51 kız, 28 erkek) olmak üzere toplam 155 çocuk çalışmaya dahil edildi. Serum vitamin B12 düzeyi ortalaması gerilim tipi baş ağrısı olanlarda 210,6±104 pg/mL (43-534 pg/mL), kontrol grubunda ise 260,6±109 pg/mL (104-712 pg/mL) idi. İki grup arasında vitamin B12 düzeyleri arasında istatiksel olarak anlamlı fark saptandı (p=0,005). Gerilim tipi baş ağrısı olan 46 hastada (%61) vitamin B12 eksikliği mevcuttu. Kontrol grubunda 30 çocukta (%38) vitamin B12 eksikliği saptandı. İki grup arasında vitamin B12 eksikliği açısından istatiksel olarak anlamlı fark saptandı (p=0,032). Sonuç: Çalışmamızda, gerilim tipi baş ağrısı olan çocukların yarısından fazlasında vitamin B12 eksikliği mevcuttu. Gerilim tipi baş ağrısı olan çocukların vitamin B12 eksikliği açısından değerlendirilmesinin önemli olacağını düşünmekteyiz.

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Cite This Article

BEKTAŞ, G., OLBAK, M. E., SARI, E., ERDİN, S., ÇİÇEK, Y. (2019). Vitamin B12 Deficiency in Children with Tension-Type Headache: Case-control Study. Bakırköy Tıp Dergisi, Cilt: 15 - Sayı: 4, 388–392. https://ajindex.com/articles/126124

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