Journals / Bakırköy Tıp Dergisi / 2019 / Cilt: 15 - Sayı: 1

Three-Dimensional Micro Structure of the Cingulum Bundle: A Fiber Dissection Study

Singulum Demeti: Üç Boyutlu Mikro Yapının Fiber Diseksiyon ile Gösterilmesi

Pages
96–102
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusions: The functional and anatomical relationships and segments of the cingulum bundle will guide the diagnosis and treatment of some psychiatric and neurological diseases.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Cingulum bundle is a major fiber tract that extends into the cingulate gyrus and reaches to the temporal tip.
📊
Key Findings & Data:Results: Singulum fiber is a long and major fiber of the brain that is approximately 9-10 cm.
💡
Conclusion & Impact:Conclusions: The functional and anatomical relationships and segments of the cingulum bundle will guide the diagnosis and treatment of some psychiatric and neurological diseases.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Cingulum bundle is a major fiber tract that extends into the cingulate gyrus and reaches to the temporal tip. It carries striatal, projection, association and commissural fibers. Therefore, it has an important role in the diagnosis and treatment of many psychiatric and neurological diseases. Our aim; to describe the structure of the cingulum fiber, to reveal its neighborhood and connections and to find an anatomical-functional classification that clinicians can use. Method: Ten human cadaver brains were prepared by using the Klingler method. In all brains, medial to lateral, inferior to superior, and superior to inferior dissection were performed. Dissection was performed under microscopic magnification. All dissection stages were visualized with the camera. Results: Singulum fiber is a long and major fiber of the brain that is approximately 9-10 cm. It starts from the orbitofrontal cortex and extends on the corpus callosum. It turns to the lateral and inferior on the splenium level. And it reaches the temporal pole. It divides into 5 segments. These are subgenual, anterior cingulate, mid-cingulate, retrosplenial and parahippocampal cingulum segments. Each segment has different projections. Conclusions: The functional and anatomical relationships and segments of the cingulum bundle will guide the diagnosis and treatment of some psychiatric and neurological diseases.

Özet

Amaç: Singulum demeti; singulat girus içinde seyredip temporal uca kadar uzana majör bir liftir. Bu lif içinde; striatal, projeksyonel, asosiyasyon ve kommisural lifler taşır. Bu nedenle birçok psikiyatrik ve nörolojik hastalığın tanı ve tedavisinde önemli bir yeri vardır. Amacımız; singulumun lifinin yapısını ayrıntılı olarak tanımlamak, komşuluklarını ve bağlantılarını ortaya koymak ve literatürden de destek alarak klinisyenlerin kullanabileceği anatomik-fonksiyonel bir sınıflama ortaya koymaktır. Yöntem: 10 adet insan kadavra beyni Klingler yöntemi kullanılarak hazırlandı. Tüm beyinlerde Medialden laterale, inferiordan süperiora ve süperiordan inferiora diseksiyon yapıldı. Diseksiyon mikroskobik büyütme altında gerçekleştirildi. Yapılan tüm diseksiyon aşamaları fotoğraf makinesi ile görüntülendi. Bulgular: Singulum lifi 9-10 cm uzunluğunda bir liftir. Orbito-frontal korteksten başlar. Korpus kallozumun süperiorunda ilerler. Spleniyum hizasında lateral ve inferiora dönüş yaparak temporal uca kadar ulaşır. Bu esnada 5 segmente ayrılır. Bunlar; Subgenual, Anterior Singulat, Mid-Singulat, Retrospleniyal ve Parahipokampal Singulum segmentleridir. Her segmentin anatomik olarak farklı projeksiyonları vardır. Sonuç: Singulum demetinin fonksiyonel ve anatomik ilişkileri ve buna bağlı segmentlere ayrılması bazı psikiyatrik ve nörolojik hastalıkların aydınlatılmasında ve tedavisinde yol gösterici olacaktır.

🔖

Cite This Article

GÜNGÖR, A., HAŞİMOĞLU, O., ÇIRAK, M., ERKAN, B. (2019). Three-Dimensional Micro Structure of the Cingulum Bundle: A Fiber Dissection Study. Bakırköy Tıp Dergisi, Cilt: 15 - Sayı: 1, 96–102. https://ajindex.com/articles/125704

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (8)

  1. Hitotsumatsu T, Matsushima T, Rhoton Jr AL. Surgical anatomy of the midface and the midline skull base. Operative Techniques in Neurosurgery. 1999;2(4):160-80.
  2. Agrawal A, Kapfhammer JP, Kress A, Wichers H, Deep A, Feindel W, et al. Josef Klingler’s models of white matter tracts: influences on neuroanatomy, neurosurgery, and neuroimaging. Neurosurgery. 2011;69(2):238-54.
  3. Locke S, Angevine JB, Jr., Yakovlev PI. Limbic nuclei of thalamus and connections of limbic cortex. II. Thalamocortical projection of the lateral dorsal nucleus in man. Arch Neurol. 1961;4:355-64. Epub 1961/04/01. PubMed PMID: 13762982. Papez JW. A proposed mechanism of emotion. Archives of Neurology & Psychiatry. 1937;38(4):725-43. Mesulam M-M. Spatial attention and neglect: parietal, frontal and cingulate contributions to the mental representation and attentional targeting of salient extrapersonal events. Philosophical Transactions of the Royal Society of London B: Biological Sciences. 1999;354(1387):1325-46.
  4. Kaada B, Pribram K, Epstein J. Respiratory and vascular responses in monkeys from temporal pole, insula, orbital surface and cingulate gyrus: a preliminary report. Journal of neurophysiology. 1949;12(5):347-56. Showers MJC. The cingulate gyrus: additional motor area and cortical autonomic regulator. Journal of Comparative Neurology. 1959;112(1):231-301. Watson CG. Abstract thinking deficit and autism in process and reactive schizophrenics. Journal of abnormal psychology. 1973;82(3):399. Morecraft RJ, Louie JL, Herrick JL, Stilwell-Morecraft KS. Cortical innervation of the facial nucleus in the non-human primate: a new interpretation of the effects of stroke and related subtotal brain trauma on the muscles of facial expression. Brain. 2001;124(1):176-208.
  5. Stuss D, Benson D, Clermont R, Della Malva C, Kaplan E, Weir W. Language functioning after bilateral prefrontal leukotomy. Brain and language. 1986;28(1):66-70.
  6. Morris JS, Öhman A, Dolan RJ. A subcortical pathway to the right amygdala mediating “unseen” fear. Proceedings of the National Academy of Sciences. 1999;96(4):1680-5. Moniz E. Prefrontal leucotomy in the treatment of mental disorders. American Journal of Psychiatry. 1937;93(6):1379-85.
  7. Wilkinson HA, Davidson KM, Davidson RI. Bilateral anterior cingulotomy for chronic noncancer pain. Neurosurgery. 1999;45(5):1129-36.
  8. Guinjoan SM, Mayberg HS, Costanzo EY, Fahrer RD, Tenca E, Antico J, et al. Asymmetrical contribution of brain structures to treatment- resistant depression as ill