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Journals / Kocatepe Tıp Dergisi / 2026 / Cilt: 25 Sayı: 1

CLINICAL SIGNIFICANCE OF HEMATOLOGICAL PARAMETERS IN CHILDREN WITH PANCREATITIS

PANKREATİTLİ ÇOCUKLARDA HEMATOLOJİK PARAMETRELERİN KLİNİK ÖNEMİ

Ayşegül Bükülmez(AFYONKARAHISAR HEALTH SCIENCES UNIVERSITY)0000-0002-6013-5172
Özge Vural(GAZI UNIVERSITY)0000-0001-7523-7553
Ahmet Ali Tuncer(AFYONKARAHISAR HEALTH SCIENCES UNIVERSITY)0000-0002-2750-7317
Pages
37–42
Publication Date
2024-01-17
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⚡ TL;DR(Too Long; Didn't Read)

CONCLUSIONS: In this study, we determined that RDW, RDWCaR, NLR and RDWPR values within the first 48 hours were important in the diagnosis and follow-up of children with AP and ARP.

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: In this study, we aimed to retrospectively evaluate the significance of new hematological parameters in the diagnosis of the inflammatory process of acute pancreatitis in children diagnosed with acute pancreatitis (AP) and acute recurrent pancreatitis (ARP).
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Key Findings & Data:MATERIAL AND METHODS: The medical records of 55 patients, who were admitted to the hospital between January 2014 and December 2019 were diagnosed with AP and ARP, were examined retrospectively.
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Conclusion & Impact:CONCLUSIONS: In this study, we determined that RDW, RDWCaR, NLR and RDWPR values within the first 48 hours were important in the diagnosis and follow-up of children with AP and ARP.
🔬Design:Araştırma Makalesi
📍Scope:2014 Verileri
⚙️Variables:Eritrosit dağılım genişliği · Pankreatit · Çocuk.

Abstract

OBJECTIVE: In this study, we aimed to retrospectively evaluate the significance of new hematological parameters in the diagnosis of the inflammatory process of acute pancreatitis in children diagnosed with acute pancreatitis (AP) and acute recurrent pancreatitis (ARP). This is the first study in the literature assessing new hematological parameters (Red cell distribution width (RDW), red cell distribution width to calcium ratio (RDWCaR), neutrophile to lymphocyte ratio (NLR), lymphocyte to monocyte ratio (LMR), platelet to lymphocyte ratio (PLR), Red cell distribution width to platelet ratio (RDWPR) and mean platelet volume (MPV)) in children with pancreatitis retrospectively. MATERIAL AND METHODS: The medical records of 55 patients, who were admitted to the hospital between January 2014 and December 2019 were diagnosed with AP and ARP, were examined retrospectively. RDW, RDWCaR, MPV, NLR, LMR, RDWPR and PLR values at 0 and 48 hours were evaluated retrospectively. Group 1 consists of patients with acute pancreatitis, Group 2 consists of patients with acute recurrent pancreatitis. A p value of <0.05 was considered statistically significant. RESULTS: RDW48h values of Group 1 and Group 2 were found to be significantly lower than RDW0h values (p<0.001 and p=0.006, respectively). RDWCaR48h values in both groups were also found to be significantly lower than RDWCaR0h (p= 0.003 and p= 0.012, respectively). NLR48h value was detected to be lower than NLR0h in Group 1 (p= 0.004). Moreover, the RDWPR48h value was found to be lower compared to RDWPR0h in Group 2 (p=0.041). CONCLUSIONS: In this study, we determined that RDW, RDWCaR, NLR and RDWPR values within the first 48 hours were important in the diagnosis and follow-up of children with AP and ARP.

Özet

AMAÇ: Bu çalışmada, akut pankreatit (AP) ve akut rekürren pankreatit (ARP) tanısı alan çocuklarda akut pankreatitin inflamatuar sürecinde tanıda yeni hematolojik parametrelerin önemini retrospektif olarak değerlendirmeyi amaçladık. Bu çalışma pankreatitli çocuklarda yeni hematolojik parametreleri; (eritrosit dağılım genişliği (RDW), eritrosit dağılım genişliği kalsiyum oranı (RDWCaR), nötrofil lenfosit oranı (NLR), lenfosit monosit oranı (LMR), trombosit lenfosit oranı (PLR), eritrosit dağılım genişliği trombosit oranı (RDWPR), ortalama trombosit hacmi (MPV))'ni retrospektif olarak değerlendiren literatürdeki ilk çalışmadır. GEREÇ VE YÖNTEM: Ocak 2014 - Aralık 2019 tarihleri arasında hastaneye başvuran ve AP ve ARP tanısı alan 55 hastanın tıbbi kayıtları geriye dönük olarak incelendi. 0 ve 48. saatlerde RDW, RDWCaR, MPVPR, NLR, LMR, RDWPR ve PLR değerleri geriye dönük olarak değerlendirildi. Grup 1 akut pankreatit, Grup 2 akut rekürren pankreatit hastalardan oluşmaktadır. İstatistiksel olarak p<0,05 değeri anlamlı kabul edildi. BULGULAR: Grup 1 ve Grup 2'nin RDW48h değerleri, RDW0h değerlerinden anlamlı derecede düşük bulundu (sırasıyla p<0,001 ve p=0,006). Her iki grupta da RDWCaR48h değerleri de RDWCaR0h'den anlamlı derecede düşük bulundu (sırasıyla p= 0,003 ve p= 0,012). Grup 1'de NLR48h değeri NLR0h'den düşük saptandı (p= 0,004). Ayrıca Grup 2'de RDWPR48h değeri RDWPR0h'ye göre daha düşük bulundu (p=0,041). SONUÇ: Bu çalışmada AP ve ARP'li çocukların tanı ve takibinde ilk 48 saat içindeki RDW, RDWCaR, NLR ve RDWPR değerlerinin önemli olduğunu belirledik.

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Cite This Article

Bükülmez, A., Vural, Ö., Tuncer, A. A. (2024). CLINICAL SIGNIFICANCE OF HEMATOLOGICAL PARAMETERS IN CHILDREN WITH PANCREATITIS. Kocatepe Tıp Dergisi, Cilt: 25 Sayı: 1, 37–42. https://doi.org/10.18229/kocatepetip.1056282

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