Journals / Kocatepe Tıp Dergisi / 2026 / Cilt: 25 Sayı: 1

EFFECT OF COMBINED EXERCISES ON IRISIN, INSULIN, LIPID PROFILE AND BODY COMPOSITION

KOMBİNE EGZERSİZLERİN İRİSİN, İNSÜLİN, LİPİD PROFİLİ VE VÜCUT BİLEŞİMİ ÜZERİNE ETKİSİ

Şeniz Karagöz(AFYON KOCATEPE ÜNİVERSİTESİ, SPOR BİLİMLERİ FAKÜLTESİ, REKREASYON BÖLÜMÜ)0000-0003-2899-1689
İrfan Yıldırım(Mersin Üniversitesi Spor Bilimleri Fakültesi)0000-0002-9632-8697
Yasin Ersöz(Mersin Üniversitesi Spor Bilimleri Fakültesi)0000-0001-5116-3246
Halit Buğra Koca(Afyon Sağlık Bilimleri Üniversitesi Tıp Fakültesi)0000-0002-5353-3228
Tülay Köken(Afyon Sağlık Bilimleri Üniversitesi Tıp Fakültesi)0000-0001-5510-9415
Pages
16–23
Publication Date
2024-01-17
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

RESULTS: As a result of the evaluation of the data, it was found that 10 weeks of regular combined exercises decreased insulin levels (p=0.003) and increased irisin levels (p=0.012) in sedentary young women.

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: Despite the indisputable beneficial effects of regular exercise on health, more data are needed on the underlying molecular pathways that regulate these effects.
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Key Findings & Data:MATERIAL AND METHODS: The sample group of the study consisted of 35 healthy sedentary young women.
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Conclusion & Impact:RESULTS: As a result of the evaluation of the data, it was found that 10 weeks of regular combined exercises decreased insulin levels (p=0.003) and increased irisin levels (p=0.012) in sedentary young women.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Egzersiz · Kadın · Hormonlar

Abstract

OBJECTIVE: Despite the indisputable beneficial effects of regular exercise on health, more data are needed on the underlying molecular pathways that regulate these effects. In this study, it was aimed to investigate the effects of regular combined exercises on serum irisin and insulin levels and lipid profile in sedentary healthy young women. MATERIAL AND METHODS: The sample group of the study consisted of 35 healthy sedentary young women. The mean age of the participants was 21.4±1.94 years, their mean height was 164.3±5.89 cm, and their body weight was 62.2±8.1 kg. The participants were given combined exercises (aerobic + resistance) for 10 weeks, 3 days a week, 75 minutes a day. The variables to be measured in the study (height, body weight, waist and hip circumference, body fat percentage, lipid profile markers, irisin and insulin hormones) were measured before starting the exercise (week 0) and after the exercise application (10 weeks). Data analysis was evaluated with a dependent sample t-test and pearson correlation test. RESULTS: As a result of the evaluation of the data, it was found that 10 weeks of regular combined exercises decreased insulin levels (p=0.003) and increased irisin levels (p=0.012) in sedentary young women. A statistically significant difference was also found in triglyceride values, which is one of the lipid profile markers (p=0.008). CONCLUSIONS: It was determined that the combined exercises performed regularly for 10 weeks have significant effects on irisin and insulin of healthy sedentary young women. It is thought that the application of aerobic and resistance exercises together is an important type of exercise to protect the public health by preventing and treating diseases caused by inactivity.

Özet

AMAÇ: Düzenli egzersizin sağlık üzerindeki tartışılmaz yararlı etkilerine rağmen, bu etkileri düzenleyen altta yatan moleküler yolaklar hakkında daha çok veriye ihtiyaç vardır.Bu çalışmada, sedanter sağlıklı genç kadınlarda düzenli kombine egzersizlerin serum irisin ve insülin düzeyleri ile lipid profili üzerine etkilerinin incelenmesi amaçlandı. GEREÇ VE YÖNTEM: Araştırmanın örneklem grubunu 35 sağlıklı genç sedanter kadın oluşturdu. Katılımcıların yaş ortalamaları 21.4±1.94 yıl, boy ortalamaları 164.3±5.89 cm ve vücut ağılıkları 62.2±8.1 kg idi. Katılımcılara 10 hafta, haftada 3 gün ve günde 75’er dakika kombine egzersizler (aerobik + direnç) yaptırıldı. Araştırmada öçülmek istenen değişkenler (boy,vücut ağırlığı, bel ve kalça çevresi,vücut yağ yüzdesi, lipit profili belirteçleri, irisin ve insülin hormonları) egzersize başlamadan önce(0.hafta) ve egzersiz uyglamasından (10.hafta) sonra ölçüldü. Verilerin analizi, bağımlı örneklem t-testi ve pearson kolerasyon testi ile değerlendirildi. BULGULAR: Verilerin değerlendirilmesi sonucunda, sedanter genç kadınlarda 10 haftalık düzenli kombine egzersizlerin insülin düzeyini azaltırken (p=0.003), irisin düzeyilerini artırdığı (p=0.012) bulunmuştur. Lipid profili belirteçlerinden biri olan trigliserit değerlerinde de istatistiksel olarak anlamlı bir fark olduğu bulunmuştur (p=0.008). SONUÇ: 10 hafta boyunca düzenli olarak yapılan kombine egzersizlerin sağlıklı sedanter genç kadınların irisin ve insülin üzerinde önemli etkileri olduğu belirlendi. Aerobik ve direnç egzersizlerinin birlikte uygulanmasının halk sağlığını korumada ve hareketsizliğin neden olduğu hastalıkları önlemede ve tedavi etmede önemli bir egzersiz türü olduğu düşünülmektedir.

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Cite This Article

Karagöz, Ş., Yıldırım, İ., Ersöz, Y., Koca, H. B., Köken, T. (2024). EFFECT OF COMBINED EXERCISES ON IRISIN, INSULIN, LIPID PROFILE AND BODY COMPOSITION. Kocatepe Tıp Dergisi, Cilt: 25 Sayı: 1, 16–23. https://doi.org/10.18229/kocatepetip.1138553

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