Journals / Kocatepe Tıp Dergisi / 2026 / Cilt: 27 Sayı: 4

DIAGNOSTIC PERFORMANCE OF PORTABLE INFRARED THERMOGRAPHY IN THYROIDITIS: A DIGITAL HEALTH APPROACH

TAŞINABİLİR KIZILÖTESİ TERMOGRAFİNİN TİROİDİTTE TANISAL PERFORMANSI: TİROİD FONKSİYONLARI VE İNFLAMATUVAR BELİRTEÇLERLE KORELASYONA DAYALI DİJİTAL SAĞLIK YAKLAŞIMI

Fatih Gürsoy(DÜZCE ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0001-8299-494X
Mehmet Emin Gönüllü(BILECIK SEYH EDEBALI UNIVERSITY)0000-0001-9126-2396
Pages
538–545
Publication Date
2026-10-12
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Prospective multicenter studies are needed to confirm these findings.

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: Infrared thermography is a noninvasive imaging technique that measures skin surface temperature and may reflect underlying inflammatory activity.
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Key Findings & Data:This study evaluated the diagnostic performance of infrared thermography in thyroiditis and its relationship with thyroid function tests (TFTs) and inflammatory markers.
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Conclusion & Impact:Prospective multicenter studies are needed to confirm these findings.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Infrared Thermography · Thyroiditis · Thyroid Function

Abstract

OBJECTIVE: Infrared thermography is a noninvasive imaging technique that measures skin surface temperature and may reflect underlying inflammatory activity. However, its diagnostic role in thyroiditis remains unclear. This study evaluated the diagnostic performance of infrared thermography in thyroiditis and its relationship with thyroid function tests (TFTs) and inflammatory markers. MATERIAL AND METHODS: This retrospective study included 144 patients (72 with thyroiditis and 72 controls). Thermal images obtained using a portable infrared thermal camera (FLIR One Edge Pro®) were analyzed. Thyroid surface temperature parameters were compared between groups and their relationship with thyroid function tests and inflammatory markers was evaluated. RESULTS: Mean thyroid surface temperature and temperature asymmetry were significantly higher in the thyroiditis group (36.8 ± 0.5 °C vs. 36.1 ± 0.4 °C; 0.54 ± 0.27 °C vs. 0.18 ± 0.09 °C; both p < 0.001). Surface temperature correlated positively with C-reactive protein (CRP) (r = 0.61) and anti–thyroid peroxidase (anti-TPO) (r = 0.57), and negatively with free thyroxine (fT4) (r = −0.52) (all p < 0.001). A temperature cut-off > 36.4 °C predicted thyroiditis with an AUC of 0.88. Multivariate analysis identified mean thyroid surface temperature (OR = 5.21), anti-TPO (OR = 3.76), and CRP (OR = 1.38) as independent predictors. CONCLUSIONS: Infrared thermography may serve as a useful noninvasive adjunct in the evaluation of thyroiditis. Elevated thyroid surface temperature and asymmetry correlate with inflammatory and biochemical markers of thyroid dysfunction. These findings suggest that thermographic assessment may contribute to clinical decision-making as a complementary tool. Prospective multicenter studies are needed to confirm these findings.

Özet

AMAÇ: Kızılötesi termografi, cilt yüzey sıcaklığını ölçen noninvaziv bir görüntüleme yöntemidir ve altta yatan inflamatuvar süreçler hakkında dolaylı bilgi sağlayabilir. Ancak tiroiditte tanısal değeri yeterince araştırılmamıştır. Bu çalışmanın amacı, kızılötesi termografinin tiroiditte tanısal performansını değerlendirmek ve tiroid fonksiyon testleri (thyroid function tests, TFTs) ile inflamatuvar belirteçlerle olan ilişkisini incelemektir. GEREÇ VE YÖNTEM: Bu retrospektif çalışmaya 144 hasta (72 tiroidit ve 72 kontrol) dahil edildi. Taşınabilir bir kızılötesi termal kamera (FLIR One Edge Pro®) ile elde edilen termal görüntüler analiz edildi. Tiroid yüzey sıcaklığı parametreleri gruplar arasında karşılaştırıldı ve tiroid fonksiyon testleri ile inflamatuvar belirteçlerle ilişkisi değerlendirildi. BULGULAR: Ortalama tiroid yüzey sıcaklığı ve sıcaklık asimetrisi tiroidit grubunda kontrol grubuna göre anlamlı derecede daha yüksekti (36,8 ± 0,5 °C vs. 36,1 ± 0,4 °C; 0,54 ± 0,27 °C vs. 0,18 ± 0,09 °C; her ikisi için p < 0,001). Ortalama yüzey sıcaklığı C-reaktif protein (C-reactive protein, CRP) (r = 0,61) ve anti-tiroid peroksidaz antikoru (anti–thyroid peroxidase, anti-TPO) (r = 0,57) ile pozitif, serbest tiroksin (free thyroxine, fT4) ile negatif korelasyon gösterdi (r = −0,52; tümü için p < 0,001). ROC analizinde ortalama yüzey sıcaklığı için >36,4 °C eşik değeri tiroiditi öngörmede AUC = 0,88 olarak bulundu. Çok değişkenli analizde ortalama tiroid yüzey sıcaklığı (OR = 5,21; p < 0,001), anti-TPO (OR = 3,76; p = 0,002) ve CRP (OR = 1,38; p = 0,008) bağımsız prediktörler olarak belirlendi. SONUÇ: Kızılötesi termografi, tiroidit değerlendirmesinde biyokimyasal ve görüntüleme bulgularına yardımcı olabilecek noninvaziv bir yöntem olabilir. Artmış tiroid yüzey sıcaklığı ve sıcaklık asimetrisi inflamatuvar aktiviteyi yansıtmakta ve laboratuvar parametreleri ile ilişkili görünmektedir. Bu nedenle, termografik değerlendirme klinik karar sürecine tamamlayıcı bir araç olarak katkı sağlayabilir. Bu bulguların doğrulanması için ileriye dönük ve çok merkezli çalışmalara ihtiyaç vardır.

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Cite This Article

Gürsoy, F., Yekenkurul, E., Çetin, M. F., Gönüllü, M. E. (2026). DIAGNOSTIC PERFORMANCE OF PORTABLE INFRARED THERMOGRAPHY IN THYROIDITIS: A DIGITAL HEALTH APPROACH. Kocatepe Tıp Dergisi, Cilt: 27 Sayı: 4, 538–545. https://doi.org/10.18229/kocatepetip.1908057

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