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Journals / Sağlık Bilimleri Dergisi / 2026 / Cilt: 31 Sayı: 2

IMPORTANCE AND POTENTIAL MECHANISMS OF GASTROINTESTINAL SYMPTOMS IN CORONAVIRUS DISEASE 2019 (COVID-19)

KORONAVİRÜS HASTALIĞI 2019 (COVID-19)’DA GASTROİNTESTİNAL BELİRTİLERİN ÖNEMİ VE OLASI MEKANİZMALARI

Zinnet Şevval Aksoyalp(İZMİR KATİP ÇELEBİ ÜNİVERSİTESİ)0000-0002-7822-3154
Nergiz Hacer Turgut(İZMİR KATİP ÇELEBİ ÜNİVERSİTESİ)0000-0003-1700-2451
Kemal Buharalıoğlu(İZMİR KATİP ÇELEBİ ÜNİVERSİTESİ)0000-0001-6077-1550
Pages
263–267
Publication Date
2022-08-11
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this way, the isolation of patients diagnosed at an early stage may help control the epidemic.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Severe acute respiratory syndrome coronavirus-2 (SARS‐CoV‐2), the Coronavirus Disease 2019 (COVID-19) agent, poses a serious threat to human health worldwide.
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Key Findings & Data:SARS-CoV-2 not only affects the respiratory system but also causes gastrointestinal system disorders such as diarrhea, nausea, and vomiting.
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Conclusion & Impact:In this way, the isolation of patients diagnosed at an early stage may help control the epidemic.
🔬Design:Derleme
📍Scope:2019 Verileri
⚙️Variables:COVID-19 · SARS-CoV-2 · diyare

Abstract

Severe acute respiratory syndrome coronavirus-2 (SARS‐CoV‐2), the Coronavirus Disease 2019 (COVID-19) agent, poses a serious threat to human health worldwide. The virus is transmitted by droplets and contact and often occurs with fever, cough, and shortness of breath. SARS-CoV-2 not only affects the respiratory system but also causes gastrointestinal system disorders such as diarrhea, nausea, and vomiting. SARS-CoV-2 has been detected in fecal samples of COVID-19 patients. Besides, diarrhea may be an early symptom for COVID-19 was suggested. Nausea, vomiting, and diarrhea are treated symptomatically in COVID-19. Consistent with these gastrointestinal symptoms, the gut microbiota balance was disturbed in COVID-19 patients, and opportunistic pathogens were increased while beneficial commensal bacteria were decreased. The gut microbiota may be a new therapeutic target for COVID-19, and these patients may benefit from probiotic treatment. Consequently, gastrointestinal symptoms should be taken into account in COVID-19 patients. In this way, the isolation of patients diagnosed at an early stage may help control the epidemic.

Özet

Şiddetli akut solunum sendromu koronavirüsü-2 (SARS‐CoV‐2) etkeninin neden olduğu koronavirüs hastalığı 2019 (COVID-19) dünya çapında insan sağlığı için ciddi bir tehdit oluşturmaktadır. Virüs damlacık ve temas yolu ile bulaşmakta ve çoğunlukla ateş, öksürük ve nefes darlığı belirtileri ile ortaya çıkmaktadır. SARS-CoV-2 solunum sistemindeki etkilerinin yanı sıra diyare, bulantı-kusma gibi gastrointestinal sistem bozukluklarına da yol açmaktadır. COVID-19 hastalarının fekal örneklerinde SARS-CoV-2 saptanmıştır. Ayrıca diyarenin COVID-19 için erken bir belirti olabileceği öne sürülmektedir. Hastalarda gözlemlenen bulantı-kusma ve diyare semptomatik olarak tedavi edilmektedir. Gastrointestinal belirtilerle uyumlu olarak COVID-19 hastalarında bağırsak mikrobiyotası dengesinin bozulduğuna dair veriler elde edilmiştir ve fırsatçı patojenlerde artış ve yararlı kommensal bakterilerde azalma görülmüştür. Bağırsak mikrobiyotasının COVID-19 için yeni bir terapötik hedef olabileceği ve bu hastaların tedavisinde probiyotiklerin fayda sağlayabileceği öne sürülmüştür. Sonuç olarak COVID-19 hastalarında gastrointestinal belirtilerin dikkate alınması gerekmektedir. Bu sayede erken dönemde tanı konulan hastaların izolasyona alınması salgının kontrol altına alınabilmesine yarar sağlayabilir.

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Cite This Article

Aksoyalp, Z. Ş., Turgut, N. H., Buharalıoğlu, K. (2022). IMPORTANCE AND POTENTIAL MECHANISMS OF GASTROINTESTINAL SYMPTOMS IN CORONAVIRUS DISEASE 2019 (COVID-19). Sağlık Bilimleri Dergisi, Cilt: 31 Sayı: 2, 263–267. https://doi.org/10.34108/eujhs.987842

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