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Journals / Dicle Üniversitesi Veteriner Fakültesi Dergisi / 2023 / Cilt: 16 Sayı: 2

Investigation of Serum Cathelicidin, Procalcitonin and Vitamin D Levels in Calves with Pneumonia

Pnömonili Buzağılarda Serum Katelisidin, Prokalsitonin ve D Vitamini Düzeylerinin Araştırılması

Mehmet Koçer(VAN YÜZÜNCÜ YIL ÜNİVERSİTESİ, SAĞLIK BİLİMLERİ ENSTİTÜSÜ, İÇ HASTALIKLARI (YL) (TEZLİ) (VETERİNER))0000-0001-8865-2932
Cumali Özkan(YÜZÜNCÜ YIL ÜNİVERSİTESİ, VETERİNER FAKÜLTESİ, KLİNİK BİLİMLER BÖLÜMÜ)0000-0001-8502-6987
Pages
65–70
Publication Date
2023-12-31
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Furthermore, it was concluded that the addition of vitamin D, Ca, Mg, and P supplements to routine calves pneumonia treatments was thought to be beneficial in the progress of the disease.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The purpose of this study was to determine the changes in serum cathelicidin, procalcitonin (PCT), vitamin D and some other biochemical parameters in calves with pneumonia and to investigate the relationship between these parameters and the disease.
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Key Findings & Data:The material of the study consisted of 40 calves, 30 of which comprised the disease group diagnosed with pneumonia and had different ages, breeds, and genders.
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Conclusion & Impact:Furthermore, it was concluded that the addition of vitamin D, Ca, Mg, and P supplements to routine calves pneumonia treatments was thought to be beneficial in the progress of the disease.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Buzağı · D vitamini · Katelisidin

Abstract

The purpose of this study was to determine the changes in serum cathelicidin, procalcitonin (PCT), vitamin D and some other biochemical parameters in calves with pneumonia and to investigate the relationship between these parameters and the disease. The material of the study consisted of 40 calves, 30 of which comprised the disease group diagnosed with pneumonia and had different ages, breeds, and genders. Besides, 10 of these calves were healthy and comprised the control group. Clinical examination of the animals were performed and blood samples were obtained for hematological and biochemical analyses. Compared to the control, it was determined that body temperature and RBC values increased significantly in animals with pneumonia. Some hematological parameters such as hematocrit (Hct), hemoglobin (Hb), white blood cell count (WBC), mean corpuscular hemoglobin (MCH) were high, while mean corpuscular volume (MCV) and thrombocyte count (THR) were found to be low, however, the changes in these parameters were not statistically significant. When compared to control group, serum cathelicidin, PCT and lactate dehydrogenase (LDH) levels were statistically higher (p<0.05, p<0.05, p<0.001, respectively). Vitamin D, calcium (Ca), phosphorus (P), magnesium (Mg) and alkalen phosphatase (ALP) levels were found to be low and vitamin D and P levels were statistically significant (p<0.05, p<0.001, respectively). As a result, in calves with pneumonia; an increase in cathelicidin, PCT, and LDH, a decrease in vitamin D, Ca, Mg, P and ALP were detected. Therefore, associated with the calves with pneumonia; cathelicidin, PCT, vitamin D, and LDH levels had alterations. Furthermore, it was concluded that the addition of vitamin D, Ca, Mg, and P supplements to routine calves pneumonia treatments was thought to be beneficial in the progress of the disease.

Özet

Bu çalışmada; pnömoni tanısı konan buzağılarda serum katelisidin, prokalsitonin (PCT), D vitamini ve bazı biyokimyasal parametre düzeylerindeki değişimlerin belirlenmesi ve bu parametrelerin hastalıkla olan ilişkilerinin araştırılması amaçlanmıştır. Pnömoni teşhisi konulan, farklı yaş, ırk ve cinsiyette 30 adet hasta buzağı (Hasta grubu) ile 10 adet sağlıklı buzağı (Kontrol grubu) olmak üzere toplam 40 adet buzağı çalışma materyalini oluşturdu. Hayvanların genel klinik muayeneleri yapılarak hematolojik ve biyokimyasal analizler için kan örnekleri alındı. Kontrol grubundaki hayvanlara göre; hasta grubundaki hayvanlarda vücut sıcaklığı ve total eritrosit sayısı (RBC) değerlerinin istatistiksel olarak artış gösterdiği, bazı hematolojik [Hematokrit (Hct), hemoglobin (Hb), total lökosit sayısı (WBC), ortalama eritrosit hemoglobini (MCH) ve ortalama eritrosit hemoglobin oranı (MCHC)] parametre değerlerinin yüksek, bazılarının [ortalama eritrosit hacmi (MCV) ve trombosit sayısı (THR)] ise düşük olduğu, ancak bu parametrelerdeki değişimlerin istatistiksel olarak anlamlı olmadığı tespit edildi. Kontrol grubu hayvanlara göre; hasta grubu hayvanlarda serum katelisidin, prokalsitonin ve laktat dehidrogenaz (LDH) değerlerinin istatistiksel olarak artış gösterdiği belirlendi (sırasıyla p 0.05). Sonuç olarak; bu çalışmada pnömonili buzağılarda katelisidin, PCT ve LDH düzeylerinde artış, D vitamini, Ca, Mg, P ve ALP seviyelerinde ise azalma olduğu belirlendi. Böylece pnömonili buzağılarda hastalıkla ilişkili olarak; katelisidin, PCT, D vitamini ve LDH düzeylerinde değişimler olduğu, pnömonili buzağılarda rutin tedavilere ek olarak D vitamini, Ca, Mg ve P takviyelerinin yapılmasının hastalığın seyrinde yararlı olabileceği kanısına varılmıştır.

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Cite This Article

Koçer, M., Özkan, C. (2023). Investigation of Serum Cathelicidin, Procalcitonin and Vitamin D Levels in Calves with Pneumonia. Dicle Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 16 Sayı: 2, 65–70. https://doi.org/10.47027/duvetfd.1291048

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