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Journals / Dicle Üniversitesi Veteriner Fakültesi Dergisi / 2026 / Cilt: 16 Sayı: 1

Serum Immunoglobulin and Nitric Oxide Levels in Calves with Arthritis and Omphalitis

Artritis ve Omfalitisli Buzağılarda Serum İmmünoglobulin ve Nitrik Oksit Seviyeleri

Caner Kayıkcı(VAN YÜZÜNCÜ YIL ÜNİVERSİTESİ, VETERİNER FAKÜLTESİ, KLİNİK BİLİMLER BÖLÜMÜ, VETERİNERLİK CERRAHİSİ ANABİLİM DALI)0000-0001-7343-1045
Musa Gençcelep(VAN YÜZÜNCÜ YIL ÜNİVERSİTESİ, VETERİNER FAKÜLTESİ, KLİNİK BİLİMLER BÖLÜMÜ, VETERİNERLİK CERRAHİSİ ANABİLİM DALI)0000-0001-6661-7079
Abdullah Karasu(VAN YÜZÜNCÜ YIL ÜNİVERSİTESİ, VETERİNER FAKÜLTESİ, KLİNİK BİLİMLER BÖLÜMÜ, VETERİNERLİK CERRAHİSİ ANABİLİM DALI)0000-0001-9443-3867
Cumali Özkan(VAN YÜZÜNCÜ YIL ÜNİVERSİTESİ, VETERİNER FAKÜLTESİ, KLİNİK BİLİMLER BÖLÜMÜ, VETERİNERLİK İÇ HASTALIKLARI ANABİLİM DALI)0000-0001-8502-6987
Loğman Aslan(VAN YÜZÜNCÜ YIL ÜNİVERSİTESİ, VETERİNER FAKÜLTESİ, KLİNİK BİLİMLER BÖLÜMÜ, VETERİNERLİK CERRAHİSİ ANABİLİM DALI)0000-0002-1567-1523
Tunahan Sancak(SİVAS CUMHURİYET ÜNİVERSİTESİ, VETERİNER FAKÜLTESİ, KLİNİK BİLİMLER BÖLÜMÜ, VETERİNERLİK CERRAHİSİ ANABİLİM DALI)0000-0002-7813-1575
Pages
1–5
Publication Date
2023-06-30
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion, no significant statistical difference was observed between serum IgA, IgM, IgG, and GGT levels of animals diagnosed with omphalitis and arthritis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Omphalitis and arthritis are diseases that are frequently encountered in calves and cause serious economic losses.
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Key Findings & Data:The animal material of this study consisted of calves with arthritis (n=20) and omphalitis (n=20) and calves (control group n=15) with clinically healthy from Van region.
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Conclusion & Impact:In conclusion, no significant statistical difference was observed between serum IgA, IgM, IgG, and GGT levels of animals diagnosed with omphalitis and arthritis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Artritis · Buzağı · İmmünoglobulin

Abstract

Omphalitis and arthritis are diseases that are frequently encountered in calves and cause serious economic losses. In this study, it was aimed to determine serum immunoglobulin and NO levels in calves with omphalitis and arthritis and to examine the changes in these parameters compared to healthy calves. The animal material of this study consisted of calves with arthritis (n=20) and omphalitis (n=20) and calves (control group n=15) with clinically healthy from Van region. Clinical and radiological examinations were carried out, and blood samples were collected. Immunoglobulin A (IgA), immunoglobulin M (IgM), immunoglobulin G (IgG), gamma-glutamyl transferase (GGT) and nitric oxide (NO) levels were determined by ELISA. In our study, mean blood serum IgA, IgM, IgG, GGT, and NO levels of calves with arthritis were found to be 0.55 mg/ml, 4.63 mg/ml, 4.33 mg/ml, 29.63 ng/ml, and 624.1 µmol/l, respectively. Mean blood serum IgA, IgM, IgG, GGT and NO levels of calves with omphalitis were 0.52 mg/ml, 4.39 mg/ml, 2.04 mg/ml, 28.51 ng/ml, 538.75 µmol/L respectively. In conclusion, no significant statistical difference was observed between serum IgA, IgM, IgG, and GGT levels of animals diagnosed with omphalitis and arthritis. While in the omphalitis group, no statistical significance was observed for the NO serum levels, a statistical significance was present in the arthritis group.

Özet

Omfalitis ve artritis buzağılarda sıklıkla karşılaşılan ve ciddi ekonomik kayıplara sebep olan hastalıklardandır. Bu çalışmada omfalitisli ve artiritisli buzağılarda serum immünoglobulin ve NO düzeylerinin belirlenmesi ve sağlıklı buzağılara göre bu parametrelerdeki değişimlerin incelenmesi amaçlanmıştır. Bu çalışmanın hayvan materyalini Van ili ve çevresinden sağlanan 20 artritisli ve 20 omfalitisli değişik ırk, yaş ve cinsiyette buzağı (çalışma grubu) ile klinik olarak sağlıklı 15 buzağı (kontrol grubu) oluşturmuştur. Hayvanların klinik ve radyolojik muayeneleri yapılarak kan örnekleri toplandı. Kan örneklerinden, immünoglobulin A (IgA), immünoglobulin M (IgM), immünoglobulin G (IgG), gama glutamil transferaz (GGT) ve nitrik oksit (NO) düzeyleri ELİSA cihazı ile tespit edildi. Çalışmamızda artritisli buzağıların ortalama kan serum IgA, IgM, IgG, GGT ve NO seviyeleri sırasıyla 0.55 mg/ml, 4.63 mg/ml, 4.33 mg/ml, 29.63 ng/ml, 624.1 µmol/L olarak bulunmuştur. Omfalitisli buzağıların ortalama kan serum IgA, IgM, IgG, GGT ve NO seviyeleri sırasıyla 0.52 mg/ml, 4.39 mg/ml, 2.04 mg/ml, 28.51 ng/ml, 538.75 µmol/L olarak bulunmuştur. Sonuç olarak, omfalitis ve artritis tanısı konan hayvanların serum IgA, IgM, IgG ve GGT seviyelerinde istatistiki olarak anlamlı bir fark gözlemlenmemiştir. Serum NO seviyelerinde ise omfalitis grubunda istatistiki olarak anlamlı bir fark gözlemlenmezken, artritis grubunda anlamlı bir fark gözlemlenmiştir.

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Cite This Article

Kayıkcı, C., Gençcelep, M., Karasu, A., Özkan, C., Aslan, L., Sancak, T. (2023). Serum Immunoglobulin and Nitric Oxide Levels in Calves with Arthritis and Omphalitis. Dicle Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 16 Sayı: 1, 1–5. https://doi.org/10.47027/duvetfd.1201969

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