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Journals / Dicle Üniversitesi Veteriner Fakültesi Dergisi / 2026 / Cilt: 19 Sayı: 1

Measurement of Some Acute Phase Proteins in Dogs with Parvoviral Enteritis

Parvoviral Enteritli Köpeklerde Bazı Akut Faz Proteinlerinin Ölçülmesi

Seren Korkmaz Erön(AFYON KOCATEPE ÜNİVERSİTESİ, SAĞLIK BİLİMLERİ ENSTİTÜSÜ)
Mustafa Kabu(AFYON KOCATEPE ÜNİVERSİTESİ, VETERİNER FAKÜLTESİ)0000-0003-0554-7278
Pages
111–115
Publication Date
2026-06-30
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Consequently, incorporating APP monitoring specifically HP and C-reactive protein (CRP) into routine protocols, alongside hemogram and albumin tracking, is crucial for early prognostic assessment, enhancing clinical decision-making, and preventing disease spread through the rapid detection of subclinical cases.

📌 3 Key Takeaways

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Objective & Hypothesis:Canine Parvovirus (CPV) is a highly contagious viral pathogen characterized by severe gastrointestinal disease, immunosuppression, and high mortality, particularly in puppies.
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Key Findings & Data:The study included a total of 40 dogs aged 0–12 months; the study group (n=30) comprised dogs confirmed CPV-positive via fecal antigen rapid test kits, while the control group (n=10) consisted of dogs assessed as clinically and hematologically healthy with negative rapid test results.
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Conclusion & Impact:Consequently, incorporating APP monitoring specifically HP and C-reactive protein (CRP) into routine protocols, alongside hemogram and albumin tracking, is crucial for early prognostic assessment, enhancing clinical decision-making, and preventing disease spread through the rapid detection of subclinical cases.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Biyobelirteç · canine parvovirus · haptoglobin

Abstract

Canine Parvovirus (CPV) is a highly contagious viral pathogen characterized by severe gastrointestinal disease, immunosuppression, and high mortality, particularly in puppies. This study aims to compare hematological, biochemical, and acute phase protein (APP) responses between dogs infected with CPV and a healthy control group, and to evaluate the prognostic significance of selected biomarkers. The study included a total of 40 dogs aged 0–12 months; the study group (n=30) comprised dogs confirmed CPV-positive via fecal antigen rapid test kits, while the control group (n=10) consisted of dogs assessed as clinically and hematologically healthy with negative rapid test results. Our findings demonstrate that hematological parameters especially serum Haptoglobin (HP) levels are significant biomarkers for assessing the severity of systemic inflammation and predicting survival in CPV infection. Consequently, incorporating APP monitoring specifically HP and C-reactive protein (CRP) into routine protocols, alongside hemogram and albumin tracking, is crucial for early prognostic assessment, enhancing clinical decision-making, and preventing disease spread through the rapid detection of subclinical cases.

Özet

Canine parvovirus (CPV), özellikle yavru köpeklerde şiddetli gastrointestinal semptomlar, immünosüpresyon ve yüksek mortalite ile karakterize, oldukça bulaşıcı viral bir patojendir. Bu çalışmanın amacı; CPV ile enfekte köpekler ile sağlıklı kontrol grubu arasındaki hematolojik, biyokimyasal ve Akut Faz Proteini (APP) yanıtlarını karşılaştırmak ve seçilen biyobelirteçlerin prognostik önemini değerlendirmektir. Çalışmaya 0–12 aylık yaş aralığında toplam 40 köpek dahil edilmiştir. Çalışma grubu (n=30), fekal antijen hızlı test kitleri ile CPV pozitifliği doğrulanan köpeklerden; kontrol grubu (n=10) ise klinik ve hematolojik açıdan sağlıklı değerlendirilen ve test sonucu negatif olan köpeklerden oluşturulmuştur. Elde edilen bulgular, hematolojik parametrelerin ve özellikle serum Haptoglobin (HP) düzeylerinin, CPV enfeksiyonunda sistemik inflamasyonun şiddetini belirlemede ve sağkalımı öngörmede önemli biyobelirteçler olduğunu göstermektedir. Sonuç olarak; CPV yönetiminde rutin hemogram ve albumin takibine ek olarak APP (özellikle HP ve CRP) izleminin protokollere dahil edilmesi; erken prognostik değerlendirme, klinik karar süreçlerinin güçlendirilmesi ve subklinik olguların tespitiyle hastalık yayılımının önlenmesi açısından kritik öneme sahiptir.

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Cite This Article

Erön, S. K., Kabu, M., *, M. K. (2026). Measurement of Some Acute Phase Proteins in Dogs with Parvoviral Enteritis. Dicle Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 19 Sayı: 1, 111–115. https://doi.org/10.47027/duvetfd.1876023

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