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Journals / Dicle Tıp Dergisi / 2026 / Cilt: 44 Sayı: 3

Trombositten zengin Fibrinin periferik sinir iyileşmesi üzerindeki histopatolojik etkileri

Hasan Metineren
Turan Cihan Dülgeroğlu
Mehmet Hüseyin Metineren
Pages
243–250
Publication Date
2017-09-20
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Bol mi k t a r da h ücr e s e l i ç er ik ve b ü y ü m e f ak t ö r ü ih t iva e d e n TZF s i n ir i y i l e ş m e s i n e o l um l u ka t k ı sa ğ la m ak t a dı r .

📌 3 Key Takeaways

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Objective & Hypothesis:A m aç : Si n ir iyi l e ş m e s i n i hı zla n dı r m a k v e kal it e s i n i a r t ı r m a k i ç in ç e ş it l i m a t er y alle r l e d e n e y s e l çal ışm ala r y a pılmıştı r .
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Key Findings & Data:Y ö n t e m l er : 16 S p r a gue D a wl e y r a t r a n d o mize i k i g u r uba ( 8 k o n t r o l , 8 TZ F ) a yr ı l dı.
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Conclusion & Impact:Bol mi k t a r da h ücr e s e l i ç er ik ve b ü y ü m e f ak t ö r ü ih t iva e d e n TZF s i n ir i y i l e ş m e s i n e o l um l u ka t k ı sa ğ la m ak t a dı r .
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Trombositten zengin fibrin · sinir iyileşmesi · deneysel rat modeli

Özet

A m aç : Si n ir iyi l e ş m e s i n i hı zla n dı r m a k v e kal it e s i n i a r t ı r m a k i ç in ç e ş it l i m a t er y alle r l e d e n e y s e l çal ışm ala r y a pılmıştı r . Ç al ışm a mızın a m ac ı t r o m b ositt e n z en g in fi b r i n in ( T Z F ) s iy a tik s i n ir iyi l e ş m e s i ü z er i n d e k i hi s t o p a to l ojik e t k i l er i n i d e n e y s e l r a t mo d e l i n d e a r a ş tı r m ak tı r . Y ö n t e m l er : 16 S p r a gue D a wl e y r a t r a n d o mize i k i g u r uba ( 8 k o n t r o l , 8 TZ F ) a yr ı l dı. Tüm r a t la r ı n s iy a tik s i n i r l e r i k e s i l ip 2mm d e f e k t l i o la r a k t e k r a r o n a r ı l dı. TZF g u r u b unda d e f e k tif b ö l g e ye TZF sa r ı l dı. 6 h a ft a n ın s o n unda r a t la r sak r if i ye e di le re k hi s to l o j ik ve im m ün o - hi s to k i my asa l m e t o t la r l a TZF n in k o n t r ol guru b u n a gö r e s i n ir o n a r ı mı n a ka t k ısı a r aş tı r ı l dı. So n u ç : TZF gur u b un u n hi s t o l ojik sk o r la r ı, k o n t r ol g u r u b una g ö r e ist a tis t i ks e l o la r a k a n la m l ı b u l undu(P=0.001 ) . TZF s i n i r le r d e aks o n a l d e v a m l ı l ı k m e v c u t tu. K o n t r ol g r ub u n da d e f e k t in t a m a m e n iyi l e ş m e d i ği y a da f i b r öz / g r a n ü l a s yon do k u yl a iyi l e ş tiği g öz l e n di. Bol mi k t a r da h ücr e s e l i ç er ik ve b ü y ü m e f ak t ö r ü ih t iva e d e n TZF s i n ir i y i l e ş m e s i n e o l um l u ka t k ı sa ğ la m ak t a dı r .

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Cite This Article

Metineren, H., Dülgeroğlu, T. C., Metineren, M. H. (2017). Trombositten zengin Fibrinin periferik sinir iyileşmesi üzerindeki histopatolojik etkileri. Dicle Tıp Dergisi, Cilt: 44 Sayı: 3, 243–250. https://doi.org/10.5798/dicletip.338997

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