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Journals / Çocuk Dergisi / 2026 / Cilt: 11 Sayı: 3

Down Syndrome and Thrombocytopenia

Down Sendromu ve Trombositopeni

Belma Saygılı Karagöl(Dr. Sami Ulus Kadın Doğum, Çocuk Sağlığı ve Hastalıkları Eğitim ve Araştırma Hastanesi, Yenidoğan Kliniği)
Arda Karagöl(Atatürk Eğitm ve Araştırma Hastanesi Psikiyatri Kliniği)
Pages
97–101
Publication Date
2011-07-01
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, we aimed to to evaluate the impact of the clinics of Down syndrome on thrombocytopenia and other hematologic parameters so as to emphasize necessary information related to the app- roach to Down syndrome and thrombocytopenia

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Down syndrome is a genetic disorder associated with vari- ous congenital anomalies and hematologic abnormalities.
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Key Findings & Data:Various hematologic disorders such as transient leukemia- like proliferative disorders, increased incidence of leuke- mia, isolated thrombocytopenia and thrombocytosis were observed in Down syndrome.
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Conclusion & Impact:In this review, we aimed to to evaluate the impact of the clinics of Down syndrome on thrombocytopenia and other hematologic parameters so as to emphasize necessary information related to the app- roach to Down syndrome and thrombocytopenia
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Down sendromu · trombositopeni · Down syndrome

Abstract

Down syndrome is a genetic disorder associated with vari- ous congenital anomalies and hematologic abnormalities. Various hematologic disorders such as transient leukemia- like proliferative disorders, increased incidence of leuke- mia, isolated thrombocytopenia and thrombocytosis were observed in Down syndrome. The etiology of thrombocyto- penia in Down syndrome is not exactly kwnown and there are limited data about this subject. In this review, we aimed to to evaluate the impact of the clinics of Down syndrome on thrombocytopenia and other hematologic parameters so as to emphasize necessary information related to the app- roach to Down syndrome and thrombocytopenia

Özet

Down sendromu, birçok doğumsal anomalilerle birlikte hematolojik bozuklukların eşlik edebildiği genetik bir has- talıktır. Lösemi benzeri geçici proliferatif bozukluk, lösemi insidansında artış, izole trombositopeni ve trombositoz gibi değişik hematolojik bozukluklar Down sendromunda sıklık- la gözlenmektedir. Down sendromunda görülen trombosi- topeninin etiyolojisi tam olarak bilinmemekte ve bu konu ile ilgili sınırlı sayıda veri bulunmaktadır. Bu makalede Down sendromu kliniğinin trombositopeni ve diğer hema- tolojik parametreler üzerine etkisinin değerlendirilerek, Down sendromu ve trombositopeni yaklaşımında gerekli bilgilerin vurgulanması amaçlanmıştır

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Cite This Article

Karagöl, B. S., Karagöl, A. (2011). Down Syndrome and Thrombocytopenia. Çocuk Dergisi, Cilt: 11 Sayı: 3, 97–101. https://doi.org/10.5222/j.child.2011.097

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