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Journals / Çocuk Dergisi / 2026 / Cilt: 22 Sayı: 2

SARS-CoV-2 Infection or Drug Allergy? Two Pediatric Cases Presenting with Angioedema

SARS-CoV-2 Enfeksiyonu mu İlaç Alerjisi mi? Anjioödem ile Gelen İki Pediatrik Olgu Sunumu

Sevgi Sipahi Çimen(Sağlık Bakanlığı Üniversitesi, Şişli Hamidiye Etfal Eğitim ve Araştırma Hastanesi, Çocuk İmmunolojisi ve Alerji Hastalıkları, İstanbul, Türkiye)0000-0003-3026-0906
Gizem Adan(Sağlık Bakanlığı Üniversitesi, Şişli Hamidiye Etfal Eğitim ve Araştırma Hastanesi, Çocuk Sağlığı ve Hastalıkları, İstanbul, Türkiye)0000-0003-2882-4178
Tolga Bacak(Sağlık Bakanlığı Üniversitesi, Şişli Hamidiye Etfal Eğitim ve Araştırma Hastanesi, Çocuk Sağlığı ve Hastalıkları, İstanbul, Türkiye)0000-0001-6646-3460
Nazan Dalgic(Sağlık Bakanlığı Üniversitesi, Şişli Hamidiye Etfal Eğitim ve Araştırma Hastanesi, Çocuk Enfeksiyon Hastalıkları, İstanbul, Türkiye)0000-0002-6516-8897
Pages
137–140
Publication Date
2022-09-09
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This article presents two pediatric cases where the patients presented with angioedema occurring in the febrile period and had drug allergy concomitant with positive SARS-CoV-2 PCR test result.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Acute urticaria and angioedema are common clinical findings in children.
📊
Key Findings & Data:Although urticaria and angioedema have frequently been seen in severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) infections during the pandemic, underlying drug and food allergies should be kept in mind in the differential diagnosis, and a detailed history should be taken from patients.
💡
Conclusion & Impact:This article presents two pediatric cases where the patients presented with angioedema occurring in the febrile period and had drug allergy concomitant with positive SARS-CoV-2 PCR test result.
🔬Design:Olgu Sunumu
📍Scope:Comprehensive Sample
⚙️Variables:Anjiyoödem · ilaç alerjisi · ürtiker

Abstract

Acute urticaria and angioedema are common clinical findings in children. Although the most common etiological factor is acute infection, drug and food allergies may also present with urticaria and angioedema. Although urticaria and angioedema have frequently been seen in severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) infections during the pandemic, underlying drug and food allergies should be kept in mind in the differential diagnosis, and a detailed history should be taken from patients. This article presents two pediatric cases where the patients presented with angioedema occurring in the febrile period and had drug allergy concomitant with positive SARS-CoV-2 PCR test result.

Özet

Akut ürtiker ve anjiyoödem çocuklarda sık görülen klinik bulgulardır. En yaygın etiyolojik faktör akut enfeksiyon olmakla birlikte, ilaç ve gıda alerjileri de ürtiker/anjiyoödem ile ortaya çıkabilir. Ürtiker ve anjiyoödem, bu pandemi döneminde Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) enfeksiyonu sırasında sık görülmekle birlikte, altta yatabilecek ilaç ve besin alerjileri ayırıcı tanıda akılda tutulmalı ve hastalardan ayrıntılı öykü alınmalıdır. Bu yazımızda ateşli dönemde ortaya çıkan anjiyo-ödem nedeniyle başvuran ve SARS-CoV-2 PCR testi pozitif olup ilaç alerjisi tanısı alan iki pediatrik vaka sunulmuştur.

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Cite This Article

Çimen, S. S., Adan, G., Bacak, T., Dalgic, N. (2022). SARS-CoV-2 Infection or Drug Allergy? Two Pediatric Cases Presenting with Angioedema. Çocuk Dergisi, Cilt: 22 Sayı: 2, 137–140. https://doi.org/10.26650/jchild.2022.927535

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