SavedAdd your journal

Journals / Ankara Üniversitesi Eczacılık Fakültesi Dergisi / 2020 / Cilt: 44 Sayı: 3

HARPAGOPHYTUM PROCUMBENS AND USE IN PHYTOTHERAPY

HARPAGOPHYTUM PROCUMBENS VE FİTOTERAPİDE KULLANIMI

Zeynep Açıkgöz(GAZİ ÜNİVERSİTESİ)0000-0001-5589-8522
Semih Bulut(GAZİ ÜNİVERSİTESİ)0000-0002-4098-0221
Didem Deliorman Orhan(Gazı University)0000-0003-3916-4048
Pages
540–556
Publication Date
2020-09-30
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Objective: In this review, general information about Harpagophytum procumbens will be given and findings of in vitro, in vivo and clinical studies on analgesic and anti-inflammatory activities will be presented.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: In this review, general information about Harpagophytum procumbens will be given and findings of in vitro, in vivo and clinical studies on analgesic and anti-inflammatory activities will be presented.
📊
Key Findings & Data:Objective: In this review, general information about Harpagophytum procumbens will be given and findings of in vitro, in vivo and clinical studies on analgesic and anti-inflammatory activities will be presented.
💡
Conclusion & Impact:Objective: In this review, general information about Harpagophytum procumbens will be given and findings of in vitro, in vivo and clinical studies on analgesic and anti-inflammatory activities will be presented.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Fitoterapi · Harpagophytum procumbens · osteoartrit

Abstract

Objective: In this review, general information about Harpagophytum procumbens will be given and findings of in vitro, in vivo and clinical studies on analgesic and anti-inflammatory activities will be presented.

Özet

Amaç: Bu derlemede, Harpagophytum procumbens ile ilgili genel bilgi verilip analjezik ve antienflamatuvar aktiviteleri üzerinde yapılmış in vitro, in vivo ve klinik çalışma bulguları sunulacaktır.

🔖

Cite This Article

Açıkgöz, Z., Bulut, S., Orhan, D. D. (2020). HARPAGOPHYTUM PROCUMBENS AND USE IN PHYTOTHERAPY. Ankara Üniversitesi Eczacılık Fakültesi Dergisi, Cilt: 44 Sayı: 3, 540–556. https://doi.org/10.33483/jfpau.680316

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (31)

  1. Lim, D.W., Kim, J.G., Han, D., Kim Y.T. (2014). Analgesic effect of Harpagophytum procumbens on postoperative and neuropathic pain in rats. Molecules, 19(1), 1060-1068.
  2. Serrano, A., Ros, G., Nieto, G. (2018). Bioactive compounds and extracts from traditional herbs and their potential anti-inflammatory health effects. Medicines, 5(3), 76.
  3. Sanders, M., Grundmann, O. (2011). The use of glucosamine, devil's claw (Harpagophytum procumbens), and acupuncture as complementary and alternative treatments for osteoarthritis. Alternative Medicine Review, 16(3), 228.
  4. Gümüş, K., Ünsal, A. (2014). Osteoartritli bireylerin günlük yaşam aktivitelerinin değerlendirilmesi. Türk Osteoporoz Dergisi, 20(3), 117-124.
  5. Altindağ, Ö., Sırmatel, Ö., Tabur, H. (2006). Diz osteoartriti olan hastalarda Demografik özellikler ve klinik parametrelerle ilişkisi. Harran Üniversitesi Tıp Fakültesi Dergisi, 3(2), 62-66.
  6. Moura, M.D.G., Lopes, L.C., Biavatti, M.W., Busse, J.W., Wang, L., Kennedy, S.A., Bhatnaga, N., Bergamaschi, C. (2016). Brazilian oral herbal medication for osteoarthritis: A systematic review protocol. Systematic Reviews, 5(1), 86.
  7. Mncwangi, N., Chen, W., Vermaak, I., Viljoen, A.M., Gericke, N. (2012). Devil's Claw- A review of the ethnobotany, phytochemistry and biological activity of Harpagophytum procumbens. Journal of Ethnopharmacology, 143(3), 755-771.
  8. Stewart, K.M., Cole, D. (2005). The commercial harvest of devil's claw (Harpagophytum spp.) in southern Africa: The devil's in the details. Journal of Ethnopharmacology, 100(3), 225-236.
  9. Street, R.A., Prinsloo, G. (2012). Commercially important medicinal plants of South Africa: A review. Plant Production. Medicinal plants of South Africa. Journal of Chemistry, 2013, Article ID 205048, 16 pages.
  10. Foundational Medicine Review site. Retrieved March 26, 2019, from https://www.foundationalmedicinereview.com/blog/resource/harpagophytum-procumbens-devils-claw/
  11. Kriukova, A.I., Vladymyrova, I.M., Gubar, S.M., Kotov, A.G., Kotova, E.E. (2018). Question introduction to the State Pharmacopoeia of Ukraine monograph «Devil’s claw root». Upravlìnnâ, Ekonomìka ta Zabezpečennâ Akostì v Farmacìï, 1(53), 6-12.
  12. Williamson, E., Driver, S., Baxter, K. (2009). Stockley's herbal medicines interactions, Pharmaceutical Press, London, p. 165.
  13. Raimondo, D., Newton, D., Fell, C., Donaldson, J.S., Dickson, B. (2005). Devil’s claw, Harpagophytum spp. in South Africa: Conservation and livelihoods issues. Traffic Bulletin, 20(3), 98-112.
  14. Anauate, M.C., Torres, L.M., de Mello, S.B.V. (2010). Effect of isolated fractions of Harpagophytum procumbens DC (Devil's claw) on COX‐1, COX‐2 activity and nitric oxide production on whole-blood assay. Phytotherapy Research, 24(9), 1365-1369.
  15. Chrubasik, S. (2004). Addendum to the ESCOP monograph on Harpagophytum procumbens. Phytomedicine, 11(7-8),691-695.
  16. European Medicines Agency site. (1995). Retrieved March 26, 2019, from https://www.ema.europa.eu/en/documents/herbal-report/final-assessment-report-harpagophytum-procumbens-dc/harpagophytum-zeyheri-decne-radix_en.pdf
  17. Mahomed, I.M., Ojewole, J.A. (2004). Analgesic, antiinflammatory and antidiabetic properties of Harpagophytum procumbens DC (Pedaliaceae) secondary root aqueous extract. Phytotherapy Research, 18(12), 982-989.
  18. Grant, L., McBean, D.E., Fyfe, L., Warnock, A.M. (2007). A review of the biological and potential therapeutic actions of Harpagophytum procumbens. Phytotherapy Research, 21(3), 199-209.
  19. Menghini, L., Recinella, L., Leone, S., Chiavaroli, A., Cicala, C., Brunetti, L., Viladimir, S., Orlando, G., Ferrante, C. (2019). Devil's claw (Harpagophytum procumbens) and chronic inflammatory diseases: A concise overview on preclinical and clinical data. Phytotherapy Research, 33(9), 2152-2162.
  20. McGregor, G., Fiebich, B., Wartenberg, A., Brien, S., Lewith, G., Wegener, T. (2005). Devil’s claw (Harpagophytum procumbens): An anti-inflammatory herb with therapeutic potential. Phytochemistry Reviews, 4(1), 47-53.
  21. Ahmed, M.I., Afifi, M.I., Younos, I.H. (2005). Harpagophytum procumbens (Devil's Claw): A possible natural anti-inflammatory agent (An experimental study). Iranian Journal of Pharmacology and Therapeutics, 4(1), 54-63.
  22. Parenti, C., Aricò, G., Chiechio, S., Di Benedetto, G., Parenti, R., Scoto, G. (2015). Involvement of the heme-oxygenase pathway in the antiallodynic and antihyperalgesic activity of Harpagophytum procumbens in rats. Molecules, 20(9), 16758-16769.
  23. Parenti, C., Aricò, G., Pennisi, M., Venditti, A., Scoto, G.M. (2016). Harpagophytum procumbens extract potentiates morphine antinociception in neuropathic rats. Natural Product Research, 30(11), 1248-1255.
  24. Huang, T.H.W., Tran, V.H., Duke, R.K., Tan, S., Chrubasik, S., Roufogalis, B.D., Duke, C.C. (2006). Harpagoside suppresses lipopolysaccharide-induced iNOS and COX-2 expression through inhibition of NF-kappa B activation. Journal of Ethnopharmacology, 104(1-2), 149-155.
  25. Kaszkin, M., Beck, K.F., Koch, E., Erdelmeier, C., Kusch, S., Pfeilschifter, J., Loew, D. (2004). Downregulation of iNOS expression in rat mesangial cells by special extracts of Harpagophytum procumbens derives from harpagoside-dependent and independent effects. Phytomedicine, 11(7-8), 585-595.
  26. Chrubasik, J.E., Lindhorst, E., Neumann, E., Gerlach, U., Faller-Marquardt, M., Torda, T., Müller-Ladner, U., Chrubasik, S. (2006). Potential molecular basis of the chondroprotective effect of Harpagophytum procumbens. Phytomedicine, 13(8), 598-600.
  27. Chantre, P., Cappelaere, A., Leblan, D., Guedon, D., Vandermander, J., Fournie, B. (2000). Efficacy and tolerance of Harpagophytum procumbens versus diacerein in treatment of osteoarthritis. Phytomedicine, 7(3), 177-183.
  28. Chrubasik, S., Thanner, J., Künzel, O., Conradt, C., Black, A., Pollak, S. (2002). Comparison of outcome measures during treatment with the proprietary Harpagophytum extract Doloteffin® in patients with pain in the lower back, knee or hip. Phytomedicine, 9(3), 181-194.
  29. Haseeb, A., Ansari, M.Y., Haqqi, T.M. (2017). Harpagoside suppresses IL‐6 expression in primary human osteoarthritis chondrocytes. Journal of Orthopaedic Research, 35(2), 311-320.
  30. Brien, S., Lewith, G.T., McGregor, G. (2006). Devil's Claw (Harpagophytum procumbens) as a treatment for osteoarthritis: a review of efficacy and safety. Journal of Alternative and Complementary Medicine, 12(10), 981-993.
  31. Brendler, T., Gruenwald, J., Ulbricht, C., Basch, E. (2006). Devil’s Claw (Harpagophytum procumbens DC) an evidence-based systematic review by the natural standard research collaboration. Journal of Herbal Pharmacotherapy, 6(1), 89-126.