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Journals / Ankara Üniversitesi Eczacılık Fakültesi Dergisi / 2020 / Cilt: 44 Sayı: 3

MOLECULAR DOCKING STUDIES ON SOME BENZAMIDE DERIVATIVES AS TOPOISOMERASE INHIBITORS

TOPOİZOMERAZ İNHİBİTÖRLERİ OLARAK BAZI BENZAMİD TÜREVLERİ ÜZERİNDE MOLEKÜLER DOKİNG ÇALIŞMALARI

Serap Yilmaz(TRAKYA ÜNİVERSİTESİ)0000-0002-6458-2658
Sanaz Ataei(ANKARA ÜNİVERSİTESİ)0000-0002-4752-1968
İlkay Yıldız(ANKARA ÜNİVERSİTESİ)0000-0001-9526-0232
Pages
470–480
Publication Date
2020-09-30
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Objective: In order to examine the interactions of some benzamide derivatives, which are thought to exhibit anti-cancer activity, with human Topo I and IIα enzymes at the molecular level, docking studies were carried out on these enzymes.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: In order to examine the interactions of some benzamide derivatives, which are thought to exhibit anti-cancer activity, with human Topo I and IIα enzymes at the molecular level, docking studies were carried out on these enzymes.
📊
Key Findings & Data:Objective: In order to examine the interactions of some benzamide derivatives, which are thought to exhibit anti-cancer activity, with human Topo I and IIα enzymes at the molecular level, docking studies were carried out on these enzymes.
💡
Conclusion & Impact:Objective: In order to examine the interactions of some benzamide derivatives, which are thought to exhibit anti-cancer activity, with human Topo I and IIα enzymes at the molecular level, docking studies were carried out on these enzymes.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Antikanser · Benzamid · Doking

Abstract

Objective: In order to examine the interactions of some benzamide derivatives, which are thought to exhibit anti-cancer activity, with human Topo I and IIα enzymes at the molecular level, docking studies were carried out on these enzymes.

Özet

Amaç: Antikanser aktivite göstereceği düşünülen Bazı benzamid türevlerinin insan Topo I ve IIα enzimleri ile moleküler düzeydeki etkileşimlerinin incelenmesi amacıyla bu enzimler üzerinden doking çalışmaları gerçekleştirilmiştir.

🔖

Cite This Article

Yilmaz, S., Ataei, S., Yıldız, İ. (2020). MOLECULAR DOCKING STUDIES ON SOME BENZAMIDE DERIVATIVES AS TOPOISOMERASE INHIBITORS. Ankara Üniversitesi Eczacılık Fakültesi Dergisi, Cilt: 44 Sayı: 3, 470–480. https://doi.org/10.33483/jfpau.789537

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