To assess the cumulative impact of the chosen variables on the nanosuspension properties, a 34 factorial design was applied and particle size and distributions were examined.
📌 3 Key Takeaways
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Objective & Hypothesis:Objective: In this study, it was aimed to prepare nanosuspensions that contains Indomethacin which is a BCS class II drug.
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Key Findings & Data:Objective: In this study, it was aimed to prepare nanosuspensions that contains Indomethacin which is a BCS class II drug.
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Conclusion & Impact:To assess the cumulative impact of the chosen variables on the nanosuspension properties, a 34 factorial design was applied and particle size and distributions were examined.
Objective: In this study, it was aimed to prepare nanosuspensions that contains Indomethacin which is a BCS class II drug. To assess the cumulative impact of the chosen variables on the nanosuspension properties, a 34 factorial design was applied and particle size and distributions were examined.
Özet
Amaç: Bu çalışmada biyofarmasötik sınıflandırma sistemine göre (BCS) 2. sınıfta bulunan indometazinin nanosüspansiyon formülasyonlarının hazırlanması ve kritik formülasyon ve işlem basamaklarının belirlenmesi amaçlanmıştır. Formülasyonların hazırlanması sırasında 34 faktöriyel tasarım uygulanmış ve partikül büyüklüğü ve dağılımı incelenmiştir.
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