Journals / Medicine Science / 2015 / Cilt: 4 Sayı: 3

Seizure Due To Hypocalcemia Caused by Late Onset Hypoparathyroism after Thyroid Surgery

Dilek Arpaci1, Mehmet Yildirim2, Nehir Ceylan2, Hasan Ergenc2, Aysel Gurkan2, Ali

Pages
2552–2558
Publication Date
2015-12-22
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Key Words: Hypocalcemia, seizure, hypoparathyroidism

📌 3 Key Takeaways

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Objective & Hypothesis:AbstractThe most common complication of thyroid surgery is hypocalcemia.
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Key Findings & Data:A 63-year-old female patient was brought to emergency department with tonic-clonic seizures she experienced for the first time in her life.
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Conclusion & Impact:Key Words: Hypocalcemia, seizure, hypoparathyroidism
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Hypocalcemia · seizure · hypoparathyroidism

Abstract

AbstractThe most common complication of thyroid surgery is hypocalcemia. Fortunately, it is often slight and transient, but sometimes it can be critical and persistent. There have been a number of reports of seizures caused by hypocalcemia following thyroid surgery. In this report, we reported a female patient who presented with tonic-clonic seizures due to hypocalcemia twenty years after thyroid surgery. A 63-year-old female patient was brought to emergency department with tonic-clonic seizures she experienced for the first time in her life. The patient’s medical history included subtotal thyroidectomy that was performed 20 years ago, although subtotal thyroidectomy, she had hypoparathyroidism and post-surgery calcitriol and calcium supplementation, and inconsistent follow-up and use of the prescribed supplements. Chvostek’s and Trousseau’s signs were present, which indicated hypocalcemia. Laboratory examination included a calcium level of 5.6 mg/ dL , an albumin level of 4.3 gr /L, a phosphorus level of 7.5 mg/ dL, a parathyroid hormone (PTH) level of 9.0 pg / mL (indicative of iatrogenic hypoparathyroidism). Parenteral calcium supplementation (200 mg calcium within 50 –100 mL 5% dextrose, intravenously, for 5-10 min) was initiated, followed immediately by oral calcium supplementation 3 g/ d, calcitriol 0.5 μg/ day, and conventional vitamin D (1000 IU/day ). During the 6 months of the outpatient follow-up, the patient did not have any other seizures and at the seventh month of the follow- up, her calcium level was measured and found to be 8.8 mg/ dL. We described a patient that presented with tonic-clonic seizures due to postoperative chronic hypoparathyroidism that was not detected before. Hypocalcemia should be considered in all the patients that present with seizure and a history of neck surgery or radiation therapy. Key Words: Hypocalcemia, seizure, hypoparathyroidism

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Cite This Article

ARPACİ, D., YİLDİRİM, M., CEYLAN, N., ERGENC, H., GURKAN, A., TAMER, A. (2015). Seizure Due To Hypocalcemia Caused by Late Onset Hypoparathyroism after Thyroid Surgery. Medicine Science, Cilt: 4 Sayı: 3, 2552–2558. https://ajindex.com/articles/1003237

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References (13)

  1. References Cmilansky P, Mrozova L. Bratisl Lek Listy. Hypocalcemia - the most common complication after total thyroidectomy. Bratisl Lek Listy. 2014;115(3):175-8. Falk S. Complications of Thyroid Surgery: Hypocalemia, Hypoparathyroidism. Raven Press,
  2. New York, NY, 1990.
  3. Reeve T, Thompson NW. Complications of thyroid surgery: how to avoid them, how to manage them, and observations on their possible effect on the whole patient. World J Surg. 2000;24(8):971-5.
  4. Quiros RM, Pesce CE, Wilhelm Sm, Djuricin G, Prinz RA. Intraoperative parathyroid hormone levels in thyroid surgery are predictive of postoperative hypothyroidism and need for vitamin D supplementation. Am J Surg. 2005;189(3):306-9.
  5. Demeester-Mirkine N, Hooghe L, Van Geertudyen J, De Maertelaer V. Hypocalcaemia after thyroidectomy. Arch Surg. 1992;127(7):854-8.
  6. Pattou F, Combemale F, Fabre S, Carnaille B, Decoulx M, Wemeau JL, Racadot A, Proye C. Hypocalcemia following thyroid surgery: incidence and prediction of outcome. World J Surg. 1998;22(7):718-24.
  7. Shaha AR, Burnett C, Jaffe BM. Parathyroid autotransplantion during thyroid surgery. J Surg Oncol. 1991;46(1):21-4.
  8. Bohrer T, Hagemeister M, Elert O.Langenbecks. A clinical chameleon: postoperative hypoparathyroidism. Arch Surg. 2007;392(4):423-6.
  9. Braunwald E, Longo DL, Fauci AS, Hauser SL, Kasper DL, Jameson JL, eds, Harrisons’ Principles of Internal Medicine, 15th edition. New York: Mc Graw–Hill. 2001;2629. Blanchard BM. Focal hypocalcemic seizures 33 years after thyroidectomy. Arch Intern Med. 1962;110:382-5. Petch CP. Hypoparathyroidism presenting with convulsions twenty seven years after thyroidectomy. Lancet. 1963;2(7299):124. Rose GA, Vas CJ. Neurological complications and electroencephalographic changes in hypoparathyroidism. Acta Neurol Scand. 1966;42(5):537-50. Cox RE. Hypoparathyroidism: an unusual cause of seizures. Ann Emerg Med. 1983;12(5):314-5.
  10. Basser LS, Neale FC, Ireland AW, Posen S. Epilepsy and electroencephalographic abnormalities in chronic surgical hypoparathyroidism. Ann Intern Med. 1969;71(3):507-15.
  11. Lehmann JB, Leidy JW Jr. A post-thyroidectomy convulsion: an unusual presentation of chronic hypoparathyroidism. W V Med J. 1994;90(10):420-1.
  12. Reddy ST, Merrick RD. Hypoparathyroidism, intracranial calcification, and seizures 61 years after thyroid surgery. Tenn Med. 1999;92(9):341-2.
  13. Halperin I, Nubiola A, Vendrell J, Vilardell E. Late-onset hypocalcemia appearing years after thyroid surgery. J Endocrinol Invest. 1989;12(6):419-20