Dergiler / Journal of the Turkish Chemical Society, Section A: Chemistry / 2016 / Cilt: 3 - Sayı: 1
Synthesis of substituted quinolinone ketones derived with some five, six and seven-membered heterocycles
- Sayfa
- 27–45
- DOI
- —
Özet
Bazı beş, altı ve yedi üyeli diaza-heterohalkalarla sübstitüe edilmiş bir seri yeni kinolinil ketonların sentezi bildirilmiştir. 6 etil-4, 5-dihidro-5, 6-dihidro-4H-pirano [3,2-c] kinolin-3-karbosaldehidin bir seri azot ve/veya 1,2- 1,3- ve 1,4- ketonları iyi verimlerle oluşturmuştur. Bütün yeni ürünlerin yapıları spektral ve analitik verilere dayanarak ortaya konmuştur.
Abstract
The synthesis of a series of new quinolinyl ketones substituted with some five, six and seven-membered diaza-heterocycles is described. Efficient base or acid-catalyzed nucleophilic heterocyclization of 6-ethyl-4,5-dioxo-5,6-dihydro-4H-pyrano[3,2-c]quinoline-3-carboxaldehyde with a variety of nitrogen and/or carbon 1,2-, 1,3-, and 1,4-binucleophiles afforded the target ketones in good yields. The structure of all new products was established on basis of their spectral and analytical data.