Dergiler / Turkish Journal of Cancer / 2001 / Cilt: 31 - Sayı: 2
Lipiodol chemoembolization and additional tamoxifen and verapamil as chemosensitizers in unresectable hepatocellular carcinoma with immunohistochemically P-glycoprotein positive case
- Sayfa
- 78–81
- DOI
- —
Özet
Lipiodol chemoembolization and additional tamoxifen and verapamil as chemosensitizers in unresectable hepatocellular carcinoma with immunohistochemically P-glycoprotein positive case
Abstract
This report describes the treatment of an advance hepatocellular carcinoma case vvhich has immunohistochemically proven P-glycoprotein positive cells, by chemoembolization and additional tamoxifen and verapamil as chemosensitizers. Chemotherapy resistance is a major problem in the treatment of patients with hepatocellular carcinoma and P-glycoprotein contributes to the resistance. Detection of P-glycoprotein positively by immunohistochemistry may affect therapy modalities in patients with hepatocellular carcinoma.