Dergiler / Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi / 2002 / Cilt: 7 - Sayı: 3
Nedeni bilinmeyen ateş: 35 olgunun analizi
- Sayfa
- 191–195
- DOI
- —
Özet
Bu çalışmada, Haziran 1993-Haziran 1999 tarihleri arasında kliniğimizde nedeni bilinmeyen ateş tanısıyla izlenen 35 olgu değerlendirilmiştir. Olguların 18 (%5l.4)'i kadın, 17 (%48.6)'si erkektir. Yaşları 14-71 arasında olup, ortalama yaş 38 olarak bulunmuştur. Hastalarda 5-58 gün arasında, ortalama 24 günde ateş etyolojisi ortaya konmuştur. Olguların 14 (%40)'ünde infeksiyon, 8 (%23)'inde kollajen vasküler hastalık, 5 (%14)'inde neoplazm, 2 (%5.7)'sinde hipersensitivite reaksiyonu, l (%2.8)'inde sarkoidoz saptanmıştır. Üç olguda etyoloji aydınlatılamamış, 2 olgu takip sırasında kaybedilmiştir, infeksiyonlar içinde 6 (%42.8) olgu ile tüberküloz ilk sırada yer alıp, bunu 4 (%28.5) olgu ile bruselloz ve ikişer (%14.2) olgu ile infektif endokardit ve intra-abdominal infeksiyon izlemektedir. Kollajen vasküler hastalıklardan 5'i Stili hastalığı, 2'si sistemik lupus eritematozis, l "i de juvenil romatoid artrit tanısı almıştır. Malignite saptanan 5 olgudan 3'ü lenfoma, l "i kolon kanseri, l'i ise malign histiyositozdur.
Abstract
In this study, 35 cases of fever of unknown origin, hospitalized at our department between June 1993 and June 1999, were evaluated. Eighteen (51.4%) of the cases were female and 17 (48.6%) were male. Ages were between 14 and 71 with a mean of 38. The diagnosis was able to be reached in 24 days (range: 5-58 days). Fourteen (40%) of the patients were found to have an infectious disease while 8 (23%) had collagen-vascular diseases, 5 (14%) had neoplasms, 2 (5.7%) had hipersensitivity reactions and I (2;8%) had sarcoidosis. No diagnosis has been established in 3 (8.5%) out of 35 patients. Two patients died during evaluation period. Among infectious diseases, tuberculosis was the leading cause with six (42.8%) cases, followed by brucellosis with 4 (28.5%) cases, 2 (14.2%) cases of infective endocarditis and 2 (14.2%) cases of intraabdominal infections. Among collagen-vascular diseases, five were Still's disease, two were sistemic lupus erythematosus and one was juvenile rheumatoid arthritis. Among 5 neoplastic diseases, 3 were (60%) lymphomas, 1 was colon carcinoma and the other was malign histiocytosis.