Journals / Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi / 2002 / Cilt: 7 - Sayı: 3
Fever of unknown origin: Analysis of 35 cases
- Pages
- 191–195
- DOI
- —
Abstract
In this study, 35 cases of fever of unknown origin, hospitalized at our department between June 1993 and June 1999, were evaluated. Eighteen (51.4%) of the cases were female and 17 (48.6%) were male. Ages were between 14 and 71 with a mean of 38. The diagnosis was able to be reached in 24 days (range: 5-58 days). Fourteen (40%) of the patients were found to have an infectious disease while 8 (23%) had collagen-vascular diseases, 5 (14%) had neoplasms, 2 (5.7%) had hipersensitivity reactions and I (2;8%) had sarcoidosis. No diagnosis has been established in 3 (8.5%) out of 35 patients. Two patients died during evaluation period. Among infectious diseases, tuberculosis was the leading cause with six (42.8%) cases, followed by brucellosis with 4 (28.5%) cases, 2 (14.2%) cases of infective endocarditis and 2 (14.2%) cases of intraabdominal infections. Among collagen-vascular diseases, five were Still's disease, two were sistemic lupus erythematosus and one was juvenile rheumatoid arthritis. Among 5 neoplastic diseases, 3 were (60%) lymphomas, 1 was colon carcinoma and the other was malign histiocytosis.
Özet
Bu çalışmada, Haziran 1993-Haziran 1999 tarihleri arasında kliniğimizde nedeni bilinmeyen ateş tanısıyla izlenen 35 olgu değerlendirilmiştir. Olguların 18 (%5l.4)'i kadın, 17 (%48.6)'si erkektir. Yaşları 14-71 arasında olup, ortalama yaş 38 olarak bulunmuştur. Hastalarda 5-58 gün arasında, ortalama 24 günde ateş etyolojisi ortaya konmuştur. Olguların 14 (%40)'ünde infeksiyon, 8 (%23)'inde kollajen vasküler hastalık, 5 (%14)'inde neoplazm, 2 (%5.7)'sinde hipersensitivite reaksiyonu, l (%2.8)'inde sarkoidoz saptanmıştır. Üç olguda etyoloji aydınlatılamamış, 2 olgu takip sırasında kaybedilmiştir, infeksiyonlar içinde 6 (%42.8) olgu ile tüberküloz ilk sırada yer alıp, bunu 4 (%28.5) olgu ile bruselloz ve ikişer (%14.2) olgu ile infektif endokardit ve intra-abdominal infeksiyon izlemektedir. Kollajen vasküler hastalıklardan 5'i Stili hastalığı, 2'si sistemik lupus eritematozis, l "i de juvenil romatoid artrit tanısı almıştır. Malignite saptanan 5 olgudan 3'ü lenfoma, l "i kolon kanseri, l'i ise malign histiyositozdur.