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AI InsightWe also demonstrated that these effects were more evident as the level of EMF was increased from 900 MHz to 1800 MHz.
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Abstract
Aim: To evaluate potential effects of whole-body 900 and 1800 MHz electromagnetic field (EMF) exposure on the rat spleen. Material and Methods: The study was conducted on 9 Sprague–Dawley rats. Pregnant rats were assigned into 3 groups: 900 MHz EMF-exposure, 1800 MHz EMF-exposure and controls. Results: Under light microscope, myeloid series cells, erythrocytes and megakaryocytes were observed in all groups. In the red pulp, dilated sinusoids were observed in both 900 and 1800 prenatal 24-hour groups with more prominent findings in the 1800 prenatal 24-hour group. Fused white pulps were apparent in 900 group while there was increase in the irregular white pulps (varying in size) with destruction in the1800 group. Biochemical evaluation showed that spleenmalondialdehyde level was higher while glutathione level waslower in the 900 MHz-exposure and 1800 MHz-exposuregroups compared to controls (p<0.05 for both). Conclusion: Based on our results, it was concluded that EMF exposure at prenatal period led pathological changes in thespleenof pups. Again, it was revealed that it led oxidative stress through enhanced lipid oxidation and altered antioxidant defense systems. We also demonstrated that these effects were more evident as the level of EMF was increased from 900 MHz to 1800 MHz.